Abstract:
:The antimicrobial activity of carumonam (formerly RO-17-2301), a monocyclic beta-lactam antibiotic, was compared with those of aztreonam, cefotaxime, cefoperazone, ceftazidime, piperacillin, and gentamicin against 455 bacterial isolates. Carumonam did not possess activity against gram-positive cocci and was generally comparable to aztreonam and ceftazidime for most gram-negative bacilli. However, carumonam was the most active beta-lactam against gentamicin-resistant Pseudomonas aeruginosa strains (90% MIC, 8 micrograms/ml).
journal_name
Antimicrob Agents Chemotherjournal_title
Antimicrobial agents and chemotherapyauthors
Smith BR,LeFrock JL,McCloskey RV,Donato JB,Weber SJ,Joseph WSdoi
10.1128/aac.29.2.346subject
Has Abstractpub_date
1986-02-01 00:00:00pages
346-9issue
2eissn
0066-4804issn
1098-6596journal_volume
29pub_type
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