Abstract:
BACKGROUND:Although reoperation likely confers survival benefit for glioblastoma, whether the extent of resection (EOR) of the reoperation affects survival outcome has yet to be thoroughly evaluated in the current temozolomide (TMZ) era. The aim of this meta-analysis was to pool the current literature and evaluate the prognostic significance of reoperation EOR for glioblastoma recurrence in the current TMZ era. METHODS:Searches of 7 electronic databases from inception to January 2019 were conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. There were 1203 articles identified for screening. Prognostic hazard ratios (HRs) for overall survival (OS) derived from multivariate regression analysis were analyzed using meta-analysis of proportions. RESULTS:Nine individual studies satisfied all selection criteria, describing survival in 1507 patients with glioblastoma, including 1335 reoperations for recurrence (89%). When studies incorporated the EOR of index surgery into their analysis, maximal resection at reoperation was significantly prognostic for longer OS (HR, 0.59; 95% confidence interval [CI], 0.43-0.79; I2 = 0%; P heterogeneity <0.01). When studies did not incorporate the EOR of index surgery into their analysis, maximal resection remained significantly prognostic for longer OS at reoperation (HR, 0.53; 95% CI, 0.45-0.64; I2 = 5.2%; P heterogeneity <0.01). Based on EOR, radiographic gross total resection (GTR) was the most prognostic EOR definition at reoperation (HR, 0.52; 95% CI, 0.44-0.61; I2 = 0%; P heterogeneity <0.01). CONCLUSIONS:In the current TMZ era, when reoperation is feasible for recurrent glioblastoma, maximal safe resection appears to confer a significant OS benefit based on the current literature. This benefit is most pronounced with radiographic GTR, and likely irrespective of EOR at index surgery.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Lu VM,Goyal A,Graffeo CS,Perry A,Burns TC,Parney IF,Quinones-Hinojosa A,Chaichana KLdoi
10.1016/j.wneu.2019.03.250subject
Has Abstractpub_date
2019-07-01 00:00:00pages
31-37eissn
1878-8750issn
1878-8769pii
S1878-8750(19)30930-1journal_volume
127pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Transforaminal endoscopic lumbar discectomy (TELD), a minimally invasive spinal technique, has advantages over open discectomy. Unilateral TELD for disc herniation causing bilateral symptoms is challenging. In this study, we describe a percutaneous endoscopic herniotomy technique by using a unilateral approa...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.06.191
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Cylindrical expandable cages are commonly used as interbody grafts after cervical, thoracic, or lumbar corpectomy in patients with osteomyelitis. Unfortunately, there is a high incidence of hardware subsidence due to small-diameter footplates. Newer expandable intervertebral cages with large rectangular endc...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2019.12.008
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:Development of immunologically smart implants, integrated to biological systems, is a key aim to minimize the inflammatory response of the host to biomaterial implants. METHODS:The aim of this study is to investigate the influence of titanium alloy and stainless steel implants on immunological responses in r...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.08.016
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:Idiopathic normal pressure hydrocephalus (iNPH) may present, besides the classic triad of symptoms, with extrapyramidal parkinsonianlike movement disorders. We present a randomized prospective study comparing adjustable ventriculoperitoneal (VP) shunt insertion plus dopamine oral therapy (group A) versus VP s...
journal_title:World neurosurgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.wneu.2016.03.004
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:Middle cerebral artery aneurysms (MCAAs) are regularly treated by both microsurgical clipping and endovascular coiling. We performed a systematic meta-analysis to compare the safety and efficacy of these 2 methods. METHODS:Literature was reviewed for all studies reporting angiographic occlusion and/or functi...
journal_title:World neurosurgery
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.wneu.2015.05.073
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To explore the feasibility and effectiveness of C1 lateral mass fixation via the posterior arch using pedicle screws of 3.5-mm diameter in patients whose atlas in the vertebral artery groove (C1 pedicle) was ≤3.5 mm in height. METHODS:A total of 14 patients who underwent transposterior arch lateral mass scre...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.03.175
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To report new results with ethylene oxide sterilization and new experiences with autogenous bone flaps autoclaved at a high or low temperature for preservation of a bone flap after decompressive craniectomy. METHODS:In 45 patients who underwent a decompressive craniectomy, we determined bone flap preservatio...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.03.042
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Arteries that anastomose with the posterior inferior cerebellar artery (PICA) can harbor aneurysms. CASE DESCRIPTION:We present a case of a patient who suffered a subarachnoid hemorrhage as a result from an aneurysm on the left lateral spinal artery (LSA) that anastomosed to the PICA. The aneurysm was treat...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.06.085
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:In this study, we retrospectively reviewed our experience in the surgical management of solitary fibrous tumor (SFT)/hemangiopericytomas (HPCs) of the spinal cord. METHODS:Sixteen patients with SFT/HPCs of the spinal cord were enrolled in this study. Data on clinical presentation, radiologic findings, histop...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.12.004
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Counts are the commonest method used to ensure that all sponges and neuropatties are removed from a surgical site before closure. When the count is not reconciled, plain radiographs of the operative site are taken to determine whether the missing patty has been left in the wound. The purpose of this study wa...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2015.03.032
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To describe epidemiology in relation to gender differences and treatment modalities 10 years after intracranial aneurysm rupture in the Stockholm cohort 1996-1999. METHODS:A total of 468 consecutive patients with aneurysmal subarachnoid hemorrhage were followed-up in a retrospective cohort design 10 years af...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2012.06.041
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Magnetic resonance imaging (MRI) plays an important role in the assessment of spinal cord status for cervical spondylotic myelopathy (CSM). Diffusion tensor imaging (DTI) also is a novel investigation tool with good sensitivity to detect changes in CSM, but it is not routinely used in spinal cord evaluation....
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.07.067
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Treating cerebral aneurysms in the M4 segment of the middle cerebral artery (MCA) is challenging because they are small and are buried in the brain parenchyma. CASE DESCRIPTION:A right-handed Asian woman in her 80s was referred to our hospital with a chief complaint of altered level of consciousness. On adm...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.08.025
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The aim of this systematic review was to compare the halo and hard collar in the management of adult odontoid fractures. METHODS:Systematic and independent searches on MEDLINE (PubMed) and the Cochrane Database of Systematic Reviews. Inclusion criteria included studies 1) with clinical outcomes, 2) in adult...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2016.10.035
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:We aimed to describe our single-center experience in treating cerebellar arteriovenous malformations (AVMs) with microsurgical resection. METHODS:During a 16-year period, 181 patients with cerebellar AVMs were surgically treated at the Department of Neurosurgery in Beijing Tiantan Hospital. Patient functiona...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.08.059
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Freehand ventriculostomy is one of the most commonly performed neurosurgical procedures. While a variety of approaches have been described, frontal via Kocher's point is the most common. Multiple trajectories have been described, but no consensus exists as to the most efficacious. Our objective was to assess...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2020.11.065
更新日期:2020-11-30 00:00:00
abstract:BACKGROUND:Large calcified intrasellar masses, called pituitary stones, have been reported as calcified pituitary adenomas in the literature. Although relatively rare, calcified pituitary adenomas appear in various formations. Thus, whether the lesion is removable-and, if so, which approach is appropriate-mainly depend...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2018.11.255
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:Epilepsy surgery is largely underused in developing counties as a result of many misconceptions. The current study evaluates complications of epilepsy surgery performed by a single surgeon from South India. METHODS:A retrospective analysis was performed of 697 consecutive patients who underwent epilepsy surg...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.03.068
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:A cavernous malformation (CM) with trigeminal neuralgia (TN) is relatively rare. We report a patient who presented with TN caused by a CM in the cerebellopontine angle. CASE DESCRIPTION:A 37-year-old man presented with a history of episodic, shock-like, right facial pain of 2 months' duration. Neurologic ex...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2019.12.167
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Osteoid osteomas (OOs) are benign bone forming tumors that, usually, occur in the extremities, with about 10% of them arising in the spine more commonly in the posterior elements. The aim of this study is to evaluate the long-term results of patients suffering from spinal OO treated with surgery and radiofre...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.10.050
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:To identify the potent metabolic biomarkers of cauda equina injury (CEI). METHODS:A total of 50 Sprague-Dawley rats were used to establish the CEI model in this study. The serum was collected at 12 hours, 1 day, 2 days, and 7 days after surgery. Ultra-high-performance liquid chromatography coupled with quadr...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.07.077
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To report our experience of endoscopic disc removal by anterior approach for management of cervical myelopathy in 210 patients. METHODS:A retrospective study of 187 cases of single- and 23 cases of double-level disc disease was performed. Cases of myelopathy with or without unilateral or bilateral radiculopa...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.04.107
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Neuronavigation has become a common means of placing pedicle screws in vertebral arthrodesis, because it reduces the incidence of complications related to poor screw positioning. OBJECTIVE:The To evaluate the accuracy of pedicle screw placement during lumbar arthrodesis performed with the new ROSA Spine rob...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.05.118
更新日期:2017-09-01 00:00:00
abstract::Ambroise Paré was celebrated surgeon of the 16th century whose practical accomplishments, books, and ideas transformed surgery and was a precursor for the later development of neurosurgery. He developed many surgical innovations related to wound management, arterial ligation for the prevention of hemorrhage during lim...
journal_title:World neurosurgery
pub_type: 传,历史文章,杂志文章,评审
doi:10.1016/j.wneu.2019.10.187
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:Muscle injury is inevitable during surgical exposure of the spine. This study compared paraspinal muscle injury after 4 surgical techniques: microdiscectomy (MD), percutaneous endoscopic lumbar discectomy (PELD), percutaneous endoscopic interlaminar discectomy (PEID), unilateral biportal endoscopic discectomy...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.05.085
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Anatomic hemispherectomy is an effective surgical treatment for patients with hemispherical intractable epilepsy. Different degrees of brain shifting have been observed, but whether these shifts can predict motor function recovery is unknown. The aim of this study was to analyze the correlation between brain...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.07.024
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:Anatomy of the posterior ascending artery (PAA) has been well documented. The PAA forms an apical arcade, which supplies the small branches to the tip of the dens. However, morphometrics of this artery such as diameter and distance from the midline, which could be applied to the diagnosis and surgical procedu...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.01.118
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Indocyanine green videoangiography (ICG-VA) after clipping can be misleading in evaluating aneurysm exclusion when the dye is injected before clipping. This is due to indocyanine green (ICG) entrapment by the clip blades in the aneurysm dome. METHODS:We examined the intraoperative findings of 7 patients pre...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.10.011
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Ventriculoperitoneal (VP) shunt surgery is the predominant mode of therapy for patients with hydrocephalus. However, it has potential complications that may require multiple surgical procedures during a patient's lifetime. The objective of this study is to review our long-term experience and evaluate the risk...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2013.01.096
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Paragangliomas are uncommon neuroendocrine tumors, rarely occurring in the lumbar spine. Primary lumbar paragangliomas are prominently vascularized, can present variably, and pose both diagnostic and surgical challenges. We report on a large case series with long-term follow-up and intraoperative footage to ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.05.144
更新日期:2020-10-01 00:00:00