Abstract：
OBJECTIVE:Diagnostic screening for functional neurological disorders (FNDs) continues to pose a challenge. Simple symptom counts fail clearly to discriminate patients with FND but there is increasing recognition of 'positive' features which are useful diagnostically during face-to-face assessments. A self-completed questionnaire evaluating specific features of FNDs would be useful for screening purposes in clinical and research settings. METHODS:The Edinburgh Neurosymptoms Questionnaire (ENS) is a 30-item survey of presence and nature of: blackouts, weakness, hemisensory syndrome, memory problems, tremor, pain, fatigue, globus, multiple medical problems, and operations constructed via literature review and expert consensus. We conducted a pilot of the ENS on new general neurology clinic attendees at a large regional neuroscience centre. Patients were grouped according to consultant neurologist impression as having symptoms that were 'Not at all', 'Somewhat', 'Largely' or 'Completely' due to a functional disorder. RESULTS:Blackouts, weakness and memory questions provided reasonable diagnostic utility (AUROC = 0.94, 0.71, 0.74 respectively) in single symptom analysis. All other symptoms lacked discriminating features. A multivariate linear model with all symptoms predicted functional classification with moderate diagnostic utility (AUROC = 0.83), specificity of 0.97, sensitivity of 0.47. Pain and blackout scores provided the most accurate predictor of functional classification. CONCLUSION:The ENS questionnaire provides some utility in differentiating patients presenting with functional blackouts but failed to provide diagnostic value in other types of FND, highlighting the limitations of this self-report tool.
journal_name
J Psychosom Resjournal_title
Journal of psychosomatic researchauthors
Shipston-Sharman O,Hoeritzauer I,Edwards M,Reuber M,Carson A,Stone Jdoi
10.1016/j.jpsychores.2019.02.005subject
Has Abstractpub_date
2019-04-01 00:00:00pages
65-73eissn
0022-3999issn
1879-1360pii
S0022-3999(18)30837-7journal_volume
119pub_type
杂志文章abstract：:Recent concerns in occupational health have shown a shift in emphasis from the study of diseases with well-established pathology toward the investigation of conditions characterized by a range of nonspecific symptoms. Exposure to potential hazards differing widely in terms of their physical nature or chemical composit...
journal_title：Journal of psychosomatic research
pub_type： 杂志文章
doi：10.1016/s0022-3999(97)00085-8
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abstract：:This study of 113 adolescent females with IDDM and their mothers investigated whether: (1) interaction patterns are more dysfunctional in families of girls with eating disturbances than in those without; and (2) the relationship between family functioning and metabolic control is mediated by an eating disturbance. Bas...
journal_title：Journal of psychosomatic research
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journal_title：Journal of psychosomatic research
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journal_title：Journal of psychosomatic research
pub_type： 杂志文章,meta分析,评审
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更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:Hospitalized patients with COVID-19 are at high risk for anxiety and depression, but most studies about mental health during the pandemic included the general public, healthcare workers, and students. We aimed to explore the anxiety and depression levels, prevalence and predictors in patients hospitalized wit...
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journal_title：Journal of psychosomatic research
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journal_title：Journal of psychosomatic research
pub_type： 杂志文章
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journal_title：Journal of psychosomatic research
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journal_title：Journal of psychosomatic research
pub_type： 杂志文章
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journal_title：Journal of psychosomatic research
pub_type： 杂志文章
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更新日期：2006-09-01 00:00:00
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journal_title：Journal of psychosomatic research
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更新日期：2019-03-01 00:00:00
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journal_title：Journal of psychosomatic research
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更新日期：2008-06-01 00:00:00
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更新日期：1990-01-01 00:00:00
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