Life events impact in patients with secondary amenorrhoea.

Abstract:

:To evaluate the relationship between stressful life events and the onset of secondary amenorrhoea Paykel's semi-structured interview for Recent Life Events was administered to patients affected by secondary amenorrhea and also to healthy volunteers. The number, quality, and objective negative impact of life events were compared among different hormonal subtypes of secondary amenorrhoea and healthy normally menstruating women, as a control group. The number of life events in amenorrhoeic patients (N = 131) was significantly greater than those observed in the control group (N = 64) (45.9 vs 32.8%). Moreover, where only hypothalamic hypogonadotrophic amenorrhoea was considered, the occurrence of life events was significantly higher (59.8%) than in hyperandrogenic (26.6%) or in normogonadotrophic (20.4%) patients. The most prevalent events among hypothalamic hypogonadotrophic amenorrhoeic patients were those classified as 'undesirable', 'uncontrolled' and with 'Objective Negative Impact'. The present study supports the hypothesis of a cause-effect relationship between stressful personal life events and the onset of secondary amenorrhoea of hypogonadotrophic subtype.

journal_name

J Psychosom Res

authors

Fioroni L,Fava M,Genazzani AD,Facchinetti F,Genazzani AR

doi

10.1016/0022-3999(94)90059-0

subject

Has Abstract

pub_date

1994-08-01 00:00:00

pages

617-22

issue

6

eissn

0022-3999

issn

1879-1360

journal_volume

38

pub_type

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