Facile synthesis and antimicrobial activity of CdS-Ag2S nanocomposites.

Abstract:

:In this study CdS-Ag2S nanocomposites for antibacterial activity were synthesized via facile co-precipitation method using PVP as capping agent. The prepared nanocomposites have particle sizes in the range of 50-100 nm (SEM) and PVP addition has good influence on the morphology of nanocomposites. The antimicrobial activity of pure Ag2S, CdS and CdS-Ag2S composites was evaluated against Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. The results demonstrate that antibacterial activity was significantly improved due to increasing ratio of CdS into CdS-Ag2S nanocomposites in comparison to pure Ag2S and CdS.

journal_name

Bioorg Chem

journal_title

Bioorganic chemistry

authors

Iqbal T,Ali F,Khalid NR,Tahir MB,Ijaz M

doi

10.1016/j.bioorg.2019.103064

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

103064

eissn

0045-2068

issn

1090-2120

pii

S0045-2068(18)31385-3

journal_volume

90

pub_type

杂志文章
  • Glycopentanolones A-D, four new geranylated quinolone alkaloids from Glycosmis pentaphylla.

    abstract::The ethanolic extract obtained from the stems of Glycosmis pentaphylla was found to suppress antigen-mediated degranulation of rat basophilic leukemia (RBL-2H3) cells. Four new geranylated 2-quinolone alkaloids, named glycopentanolones A-D (1-4), and 12 known metabolites (5-16) were isolated from the ethanolic extract...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2019.03.069

    authors: Choi YH,Seo C,Jeong W,Lee JE,Lee JY,Ahn EK,Kang JS,Lee JH,Choi CW,Oh JS,Lee D,Hong SS

    更新日期:2019-06-01 00:00:00

  • Monoterpene indole alkaloids with acetylcholinesterase inhibitory activity from the leaves of Rauvolfia vomitoria.

    abstract::Seventeen monoterpene indole alkaloids, including seven new alkaloids (1-7) and ten known analogues (8-17), were isolated and identified from the leaves of R. vomitoria. The structures of new alkaloids were elucidated by extensive spectroscopic analysis and single-crystal X-ray diffraction analysis. Rauvomitorine I (1...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104136

    authors: Zhan G,Miao R,Zhang F,Chang G,Zhang L,Zhang X,Zhang H,Guo Z

    更新日期:2020-09-01 00:00:00

  • Synthesis, in silico and in vitro studies of new 1,4-dihydropiridine derivatives for antitumor and P-glycoprotein inhibitory activity.

    abstract::P-glycoprotein (P-gp) is one of the cell membrane pumps which mediate the efflux of molecules such as anticancer drugs to the extracellular matrix of tumor cells. P_gp is a member of the ATP-binding cassette (ABC) transporter family that is implicated in cancer multidrug resistance (MDR). Since MDR is a contributor to...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2019.103156

    authors: Mollazadeh S,Sahebkar A,Kalalinia F,Behravan J,Hadizadeh F

    更新日期:2019-10-01 00:00:00

  • Predominant role of basicity of leaving group in alpha-effect for nucleophilic ester cleavage.

    abstract::It has been found that alpha-effects in nucleophilic reactions, unexpectedly large nucleophilicity due to adjacent unpaired electrons, are strongly dependent on the structure of substrate. The nucleophilic cleavages of 4-nitrobenzoate esters and 4-methylbenzoate esters by HOO- have been systematically investigated in ...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2003.09.003

    authors: Nomura Y,Kubozono T,Hidaka M,Horibe M,Mizushima N,Yamamoto N,Takahashi T,Komiyama M

    更新日期:2004-02-01 00:00:00

  • Discovery of monoamine oxidase A inhibitory peptides from hairtail (Trichiurus japonicus) using in vitro simulated gastrointestinal digestion and in silico studies.

    abstract::The aim of this study was to effectively obtain monoamine oxidase A (MAO-A) inhibitory peptides from in vitro simulated gastrointestinal digestion and to assess the correspondences between in silico prediction and in vitro confirmation. Fractions (<3 kDa) from ultrafiltration of pepsin and simulated gastrointestinal e...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104032

    authors: Yang X,Wang K,Liu Q,Zhang X

    更新日期:2020-08-01 00:00:00

  • Substituted 1,3-dioxoisoindoline-4-aminoquinolines coupled via amide linkers: Synthesis, antiplasmodial and cytotoxic evaluation.

    abstract::Synthesis of C-5-substituted 1,3-dioxoisoindoline-4-aminoquinolines having amide group as a spacer was developed with an intent to evaluate their antiplasmodial activities. The synthesized dioxoisoindoline-aminoquinolines tethered with β-alanine as a spacer and secondary amine as substituent displayed good anti-plasmo...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2019.04.006

    authors: Rani A,Legac J,Rosenthal PJ,Kumar V

    更新日期:2019-07-01 00:00:00

  • Design, synthesis, biological evaluation and in silico studies of novel pyrrolo[3,4-d]pyridazinone derivatives withpromising anti-inflammatory and antioxidant activity.

    abstract::Novel Mannich base analogues of pyrrolo[3,4-d]pyridazinone 7a,b-13a,b are designed and synthesized as potential anti-inflammatory agents. The title compounds are obtained via convenient one-pot synthesis with good yields. Their structures and properties are described by spectroscopic techniques and elemental analyses....

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104035

    authors: Szczukowski Ł,Redzicka A,Wiatrak B,Krzyżak E,Marciniak A,Gębczak K,Gębarowski T,Świątek P

    更新日期:2020-09-01 00:00:00

  • A new nonhydrolyzable reactive cAMP analog, (Sp)-adenosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase.

    abstract::Levels of cAMP that control critical platelet functions are regulated by cGMP-inhibited cAMP phosphodiesterase (PDE3A). We previously showed that millimolar concentrations of the hydrolyzable 8-[(4-bromo-2,3-dioxobutyl)thioadenosine 3',5'-cyclic monophosphate (8-BDB-TcAMP) inactivate PDE3A. We have now synthesized a n...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1006/bioo.2001.1226

    authors: Hung SH,Madhusoodanan KS,Beres JA,Boyd RL,Baldwin JL,Zhang W,Colman RW,Colman RF

    更新日期:2002-02-01 00:00:00

  • Bioactive secondary metabolites from the marine-associated fungus Aspergillus terreus.

    abstract::Three new compounds, including a prenylated tryptophan derivative, luteoride E (1), a butenolide derivative, versicolactone G (2), and a linear aliphatic alcohol, (3E,7E)-4,8-dimethyl-undecane-3,7-diene-1,11-diol (3), together with nine known compounds (4-12), were isolated and identified from a coral-associated fungu...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2018.06.029

    authors: Liu M,Sun W,Wang J,He Y,Zhang J,Li F,Qi C,Zhu H,Xue Y,Hu Z,Zhang Y

    更新日期:2018-10-01 00:00:00

  • Probing phenylcarbamoylazinane-1,2,4-triazole amides derivatives as lipoxygenase inhibitors along with cytotoxic, ADME and molecular docking studies.

    abstract::Hunting small molecules as anti-inflammatory agents/drugs is an expanding and successful approach to treat several inflammatory diseases such as cancer, asthma, arthritis, and psoriasis. Besides other methods, inflammatory diseases can be treated by lipoxygenase inhibitors, which have a profound influence on the devel...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104525

    authors: Muzaffar S,Shahid W,Riaz N,Saleem M,Ashraf M,Aziz-Ur-Rehman,Bashir B,Kaleem A,Al-Rashida M,Baral B,Bhattarai K,Gross H

    更新日期:2020-12-03 00:00:00

  • Ursolic and oleanolic acid derivatives with cholinesterase inhibiting potential.

    abstract::Triterpenoids are in the focus of scientific interest, and they were evaluated for many pharmacological applications among them their ability to act as inhibitors of cholinesterases. These inhibitors are still of interest as drugs that improve the life quality of patients suffering from age-related dementia illnesses ...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2018.12.013

    authors: Loesche A,Köwitsch A,Lucas SD,Al-Halabi Z,Sippl W,Al-Harrasi A,Csuk R

    更新日期:2019-04-01 00:00:00

  • Design, synthesis and melatoninergic potency of new N-acyl 8,9-dihydro-4-methoxy-7H-2-benzo[de]quinolinalkanamines.

    abstract::A series of new N-acyl 8,9-dihydro-4-methoxy-7H-2-benzo[de]quinolinalkanamines have been prepared and tested for their ability to activate pigment granule aggregation in Xenopus laevis melanophores and bind to the recombinant human MT(1) and MT(2) melatonin receptor subtypes expressed in NIH 3T3 cells. Compounds with ...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2006.11.006

    authors: Tsotinis A,Eleutheriades A,Hough KA,Davidson K,Sugden D

    更新日期:2007-04-01 00:00:00

  • Recent advances in synthesis and medicinal chemistry of benzodiazepines.

    abstract::Benzodiazepines (BZDs) represent a diverse class of bicyclic heterocyclic molecules. In the last few years, benzodiazepines have emerged as potential therapeutic agents. As a result, several mild, efficient and high yielding protocols have been developed that offer access to various functionalized benzodiazepines (BZD...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.bioorg.2020.103668

    authors: Arora N,Dhiman P,Kumar S,Singh G,Monga V

    更新日期:2020-04-01 00:00:00

  • Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation.

    abstract::Epigenetics plays a fundamental role in cancer progression, and developing agents that regulate epigenetics is crucial for cancer management. Among Class I and Class II HDACs, HDAC8 is one of the essential epigenetic players in cancer progression. Therefore, we designed, synthesized, purified, and structurally charact...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.103934

    authors: Upadhyay N,Tilekar K,Jänsch N,Schweipert M,Hess JD,Henze Macias L,Mrowka P,Aguilera RJ,Choe JY,Meyer-Almes FJ,Ramaa CS

    更新日期:2020-07-01 00:00:00

  • Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.

    abstract::In the present study, 7-subsituted coumarin derivatives were synthesized using various aromatic and heterocyclic amines, and evaluated in vivo for anti-inflammatory and analgesic activity, and for ulcerogenic risk. The most active compounds were evaluated in vitro for 5-lipoxygenase (5-LOX) inhibition. Docking study w...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2016.06.004

    authors: Srivastava P,Vyas VK,Variya B,Patel P,Qureshi G,Ghate M

    更新日期:2016-08-01 00:00:00

  • Caffeine-hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells.

    abstract::We report design and synthesis of set of novel anticancer agents based on caffeine-hydrazones bearing 2-hydroxyaryl- or 2-N-heteroaryl moiety. Anticancer activity evaluation using seven cancer cell lines and two non-malignant cell lines demonstrated that several derivatives display significant anticancer activity and ...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2015.03.003

    authors: Kaplánek R,Jakubek M,Rak J,Kejík Z,Havlík M,Dolenský B,Frydrych I,Hajdúch M,Kolář M,Bogdanová K,Králová J,Džubák P,Král V

    更新日期:2015-06-01 00:00:00

  • Synthesis of triphenylphosphonium dibenzothiophene S-oxide derivatives and their effect on cell cycle as photodeoxygenation-based cytotoxic agents.

    abstract::Photodeoxygenation of Dibenzothiophene-S-oxide (DBTO) in UV-A light produces atomic oxygen [O(3P)] and the corresponding sulfide, dibenzothiophene (DBT). Recently, DBTO has been derivatized to study the effect of UV-A light-driven photodeoxygenation in lipids, proteins, and nucleic acids. In this study, two DBTO deriv...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104442

    authors: Isor A,O'Dea AT,Petroff JT 2nd,Skubic KN,Grady SF,Arnatt CK,McCulla RD

    更新日期:2020-12-01 00:00:00

  • Design and synthesis of donepezil analogues as dual AChE and BACE-1 inhibitors.

    abstract::Multi-target-directed ligands (MTDLs) centered on β-secretase 1 (BACE-1) inhibition are emerging as innovative therapeutics in addressing the complexity of neurodegenerative diseases. A new series of donepezil analogues was designed, synthesized and evaluated as MTDLs against neurodegenerative diseases. Profiling of d...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2018.06.031

    authors: Gabr MT,Abdel-Raziq MS

    更新日期:2018-10-01 00:00:00

  • A novel amino cellulose derivative using ATRP method: Preparation, characterization, and investigation of its antibacterial activity.

    abstract::In this study, we prepared a novel amino cellulose derivative (benzyl cellulose-g-poly [2-(N,N-Dimethylamino)ethyl methacrylate]) via a homogeneous ATRP method. The successful synthesis of the novel amino cellulose was confirmed by FT-IR and 1H NMR. This study addressed the different characteristics of the prepared po...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104355

    authors: Shokri M,Moradi S,Amini S,Shahlaei M,Seidi F,Saedi S

    更新日期:2021-01-01 00:00:00

  • Synthesis and in vitro antitumor activity of novel acylspermidine derivative N-(4-aminobutyl)-N-(3-aminopropyl)-8-hydroxy-dodecanamide (AAHD) against HepG2 cells.

    abstract::Naturally occurring polyamines like Putrescine, Spermidine, and Spermine are polycations which bind to the DNA, hence stabilizing it and promoting the essential cellular processes. Many synthetic polyamine analogues have been synthesized in the past few years, which have shown cytotoxic effects on different tumours. I...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2019.102937

    authors: Al-Malki AL,Razvi SS,Mohammed FA,Zamzami MA,Choudhry H,Kumosani TA,Balamash KS,Alshubaily FA,ALGhamdi SA,Abualnaja KO,Abdulaal WH,Zeyadi MA,Al-Zahrani MH,Alhosin M,Asami T,Moselhy SS

    更新日期:2019-07-01 00:00:00

  • Structure-activity relationship studies of prostate-specific membrane antigen (PSMA) inhibitors derived from α-amino acid with (S)- or (R)-configuration at P1' region.

    abstract::Prostate-specific membrane antigen (PSMA), a type II membrane glycoprotein, is considered an excellent target for the diagnosis or treatment of prostate cancer. We previously investigated the effect of β- and γ-amino acids with (S)- or (R)-configuration in the S1 pocket on the binding affinity for PSMA. However, compr...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104304

    authors: Kwon H,Lim H,Ha H,Choi D,Son SH,Nam H,Minn I,Byun Y

    更新日期:2020-11-01 00:00:00

  • Targeted dendrimers for antagonizing the migration and viability of NALM-6 lymphoblastic leukemia cells.

    abstract::Acute lymphoblastic leukemia (ALL) or white blood cell cancer is one of the major causes that kills many children worldwide. Although various therapeutic agents are available for ALL treatment, the new drug discovery and drug delivery system are needed to improve their effectiveness, to reduce the toxicity and side-ef...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104601

    authors: Chittasupho C,Aonsri C,Imaram W

    更新日期:2021-01-01 00:00:00

  • Rational design of pyrrolo.

    abstract::Models have been developed for the interaction of the pyrrolo[1,2-a]benzimidazole (PBI) antitumor agents with the two-electron activating enzyme DT-diaphorase and the DNA major groove. The DT-diaphorase model and experimental results indicate that the S-enantiomer of 3-carbamido PBI can enantioselect ovarian cancers. ...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1006/bioo.2000.1183

    authors: Huang X,Suleman A,Skibo EB

    更新日期:2000-12-01 00:00:00

  • Design, synthesis and photoinduced DNA cleavage studies of [1,2,4]-triazolo[4,3-a]quinoxalin-4(5H)-ones.

    abstract::An expedient and eco-friendly synthesis of 1-aryl/heteroaryl-[1,2,4]-triazolo[4,3-a]quinoxalin-4(5H)-ones (4) has been accomplished via iodobenzene diacetate mediated oxidative intramolecular cyclization of 3-(2-(aryl/heteroarylidene)hydrazinyl)-quinoxalin-2(1H)-ones (3). Ten synthesized compounds 3 and 4 (10-40 μg) o...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2019.102932

    authors: Sumran G,Aggarwal R,Mittal A,Aggarwal A,Gupta A

    更新日期:2019-07-01 00:00:00

  • Design, synthesis and biological evaluation of novel β-pinene-based thiazole derivatives as potential anticancer agents via mitochondrial-mediated apoptosis pathway.

    abstract::A series of novel β-pinene-based thiazole derivatives were synthesized and characterized by HRMS, 1H NMR, and 13C NMR analyses as potential antineoplastic agents. Derivatives were evaluated for their anticancer activities in vitro, and the data manifested that most target compounds showed potent anti-proliferative act...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2018.12.010

    authors: Wang Y,Wu C,Zhang Q,Shan Y,Gu W,Wang S

    更新日期:2019-03-01 00:00:00

  • Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain.

    abstract::A series of novel quinazolines as tubulin inhibitors occupying three zones of colchicine domain have been designed and synthesized inspired by the recently disclosed crystal structure of verubulin analogue 6 with tubulin. Among the newly synthesized compounds, 19c showed noteworthy potency against K562, HepG2, KB, HCT...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2018.10.027

    authors: Li W,Yin Y,Shuai W,Xu F,Yao H,Liu J,Cheng K,Xu J,Zhu Z,Xu S

    更新日期:2019-03-01 00:00:00

  • Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII.

    abstract::Building on the conclusions of previous inhibition studies with pyridinium-benzenesulfonamides from our team and on the X-ray crystal structure of the lead compound identified, a series of 24 pyridinium derivatives of 3-aminobenzenesulfonamide was synthesized and investigated for carbonic anhydrase inhibition. The new...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.104204

    authors: Akocak S,Güzel-Akdemir Ö,Kishore Kumar Sanku R,Russom SS,Iorga BI,Supuran CT,Ilies MA

    更新日期:2020-10-01 00:00:00

  • Synthesis, biological evaluation and molecular docking studies of bis-chalcone derivatives as xanthine oxidase inhibitors and anticancer agents.

    abstract::In this study, a series of B-ring fluoro substituted bis-chalcone derivatives were synthesized by Claisen-Schmidt condensation reactions and evaluated for their ability to inhibit xanthine oxidase (XO) and growth inhibitory activity against MCF-7 and Caco-2 human cancer cell lines, in vitro. According to the results o...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2019.103149

    authors: Burmaoglu S,Ozcan S,Balcioglu S,Gencel M,Noma SAA,Essiz S,Ates B,Algul O

    更新日期:2019-10-01 00:00:00

  • Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents.

    abstract::Molecules capable of engaging with multiple targets associated with pathological condition of Alzheimer's disease have proved to be potential anti-Alzheimer's agents. In our goal to develop multitarget-directed ligands for the treatment of Alzheimer's disease, a novel series of carbazole-based stilbene derivatives wer...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2020.103977

    authors: Patel DV,Patel NR,Kanhed AM,Teli DM,Patel KB,Joshi PD,Patel SP,Gandhi PM,Chaudhary BN,Prajapati NK,Patel KV,Yadav MR

    更新日期:2020-08-01 00:00:00

  • Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities.

    abstract::Two new series of ethyl benzoate bearing pyrrolizine and indolizine moieties 8-11 were synthesized and evaluated for their anti-inflammatory and anticancer activities. Among these derivatives, compounds 9a, 10b and 11b displayed in vivo anti-inflammatory and analgesic activity comparable to ibuprofen. The acute ulcero...

    journal_title:Bioorganic chemistry

    pub_type: 杂志文章

    doi:10.1016/j.bioorg.2019.103371

    authors: Attalah KM,Abdalla AN,Aslam A,Ahmed M,Abourehab MAS,ElSawy NA,Gouda AM

    更新日期:2020-01-01 00:00:00