Abstract:
BACKGROUND:Conjoined twins are rare developmental anomalies. There is a paucity of literature other than case reports and small case series. The aim of this study was to examine national outcomes and identify predictors of mortality in newborn conjoined twins. METHODS:We reviewed data on newborn conjoined twins from the Kids' Inpatient Database (1997-2012). RESULTS:A total of 240 patients were identified for a nationally weighted incidence of 1 per 100,000 live births. The majority of conjoined twins were female (n = 190 [81%]). The most commonly associated anomalies were cardiac (n = 87 [36%]), gastrointestinal (n = 41 [17%]), and abdominal wall (n = 32 [13%]) defects. Fifty-six (23%) patients underwent operative procedures, including 28 (12%) neonatal separation surgeries. The overall mortality rate was 61%; most deaths occurred within 24 hours (99 of 146 [68%]) to 48 hours (129 of 146 [88%]) after birth. Mortality was higher in female compared with male children (66% vs 38%, P = .025), premature compared with full-term children (72% vs 44%, P = .007), and in children with extremely low birth weight (95% vs 59%, P = .002). Congenital diaphragmatic hernias were seen in 15 (6%) patients and were uniformly fatal (100% vs 58%, P = .029). Mortality was highest in hospitals not designated as children's hospitals (72%) compared with children's hospitals (44%) (P = .007). CONCLUSION:Conjoined twins are rare anomalies who are susceptible to extremely high perinatal mortality, especially in female children, those who are premature, or those who have low birth weight. These data support caring for these complex patients at hospitals equipped to care for this fragile population.
journal_name
Surgeryjournal_title
Surgeryauthors
Willobee BA,Mulder M,Perez EA,Hogan AR,Brady AC,Sola JE,Thorson CMdoi
10.1016/j.surg.2019.06.028subject
Has Abstractpub_date
2019-11-01 00:00:00pages
854-860issue
5eissn
0039-6060issn
1532-7361pii
S0039-6060(19)30418-0journal_volume
166pub_type
杂志文章相关文献
SURGERY文献大全abstract:BACKGROUND:This study was performed to assess the relationship between Hashimoto's thyroiditis and the development, presentation, management, and outcome of papillary thyroid carcinoma. METHODS:Two complementary analytic methods were used. The clinical study was a retrospective case-control study, including patients s...
journal_title:Surgery
pub_type: 杂志文章,meta分析
doi:10.1067/msy.2099.101431
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Endoscopic endocrine neck surgery requires insufflation with carbon dioxide (CO(2)) at 10 to 15 mm Hg, which may decrease the cerebral venous return and increase intracranial pressure. This study evaluated the effect of CO(2) neck insufflation on intracranial pressure (ICP) and hemodynamic parameters. METHO...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2000.110238
更新日期:2000-12-01 00:00:00
abstract::The central venous dialysis catheter has gained wide acceptance for short-term hemodialysis with the realization of the need to spare peripheral extremity vessels for the creation of more durable internal arteriovenous fistulas. The Hemocath (Quinton Instrument Co., Seattle, Wash.), a soft, silicone rubber, double-lum...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1987-11-01 00:00:00
abstract:BACKGROUND:We wished to determine the role and significance of preoperative chemotherapy and radiotherapy in management of operable cancer of the esophagus. METHODS:Twenty-two patients with clinical stage I-II cancer of the esophagus were entered in a prospective study of preoperative chemotherapy (5-fluorouracil/cisp...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:Recent studies suggest that low computed tomography (CT) attenuation values can be used to differentiate benign adrenal adenomas from non-adenomas. We examined the utility of non-enhanced CT attenuation values of journal_title:Surgery pub_type: 杂志文章 doi:10.1067/msy.2001.119189 更新日期:2001-12-01 00:00:00
abstract::Abdominal wall defects created in Sprague-Dawley rats were repaired with either polypropylene mesh (PPM) or expanded polytetrafluoroethylene patch (PTFE). Tensiometric studies of abdominal wall strength showed that PPM and expanded PTFE provided a strong repair in uninfected wounds. Wounds reconstructed with expanded ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::A prospective, randomized clinical trial of three treatment regimens: (1) Cytoxan, methotrexate, and 5-fluorouracil (CMF), (2) CMF plus the antiestrogen drug, tamoxifen (CMFT), and (3) CMFT plus bacillus Calmette-Guerin (BCG) vaccinations in women with stage 22 breast cancer is reported. All patients underwent mastect...
journal_title:Surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1980-05-01 00:00:00
abstract:BACKGROUND:Pathways critical for neuroblastoma cancer stem cell function are targeted by 4,19,27-triacetyl withalongolide A (WGA-TA). Because neuroblastoma cells and their cancer stem cells highly overexpress the scavenger receptor class B type 1 receptor that binds to synthetic high-density lipoprotein, we hypothesize...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.01.023
更新日期:2018-05-09 00:00:00
abstract::The efficacy of nasogastric (NG) suction was evaluated in a prospective, randomized trial in 60 patients with acute pancreatitis of mild to moderate severity. Group I, NG (29 patients) was treated with NG suction, and group II, no NG (31 patients) was treated without NG suction. The presentation, cause of pancreatitis...
journal_title:Surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1986-09-01 00:00:00
abstract::Tissue oxygen tensions in healing anastomoses of rabbit abdominal aortas were measured with ultramicro-oxygen cathodes with 1 to 3 mum tips. Two days after constructing the anastomosis, the over-all profile of intramural oxygen tension was different markedly from that of normal aortic wall, showing a progressive fall ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1975-08-01 00:00:00
abstract:BACKGROUND:Previous evaluations of the oncologic efficacy of minimally invasive approaches to total gastrectomy in gastric adenocarcinoma have been limited by sample size and duration of follow-up. METHODS:We queried the National Cancer Database to identify patients undergoing robotic and laparoscopic or open total ga...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2019.05.041
更新日期:2019-10-01 00:00:00
abstract::Hemolytic uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and acute renal failure, usually in children under 10 years of age. Gastrointestinal symptoms, including abdominal pain and bloody diarrhea, frequently precede the onset of renal failure. It has not been generally appreciated that ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract::The accuracy of oculoplethysmography (OPG) and carotid phonoangiography (CPA) singly and in combination, the Doppler velocity detector, and photoplethysmography (PPG) was checked by measurement of the degree of stenosis as shown on arteriograms in 308 internal carotid arteries. In a second study using arteriographic m...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract::The adrenal glands removed from mongrel adult dogs were used to evaluate calcitonin activity; calcitonin has been recognized since 1962 as being a potent hypocalcemic polypeptide. After removal of the glands the animals demonstrated a significant hypocalcemic period simulating a one-half maximal calcitonin effect, wh...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1969-07-01 00:00:00
abstract::Diffuse compensatory extramedullary hematopoiesis is well known to involve the spleen and liver in certain hematologic disorders. Hematopoietic tumor masses occasionally form and usually occur paraspinally in the posterior mediastinum. A 31-year-old patient with thalassemia is described with a massive, solitary, intra...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::Social media is a necessary component of the practice of surgery. Each surgeon must embrace the power and potential of social media and serve as a guide or content expert for patients and other health care providers to facilitate and share responsible use of the various media available. Social media facilitates rapid ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.06.002
更新日期:2015-09-01 00:00:00
abstract::Hepatic ultrasonography (US) was performed during laparotomy in 47 patients with hepatocellular carcinomas (HCC) less than 5 cm in size. It detected more tumors than did preoperative US and other imaging modalities. In this series, 45.9% of HCCs smaller than 3 cm and 14.2% of those between 3 and 5 cm were invisible an...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Outcome for most abdominal wall defects is related to the presence or absence of additional anomalies or prematurity. In gastroschisis, outcome is almost as closely related to the severity of the inflammatory "peel" on bowel that is thought to result from direct contact with amniotic fluid. Improving eviscer...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to determine performance retention after initial and ongoing Fundamentals of Laparoscopic Surgery (FLS) skills training. METHODS:Surgery residents (postgraduate year [PGY] 1-5; n = 91) initially underwent proficiency-based training during a 2-month period for all 5 FLS tasks. S...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2009.05.009
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Central gastrectomy (CG) for gastric cancer was developed to preserve pyloric function and maintain a large gastric volume. Whether this procedure is feasible for limited cases of gastric cancer is unclear. METHODS:On the basis of Union Internationale Contre le Cancer TNM classification, pathologic characte...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2003.33
更新日期:2003-01-01 00:00:00
abstract::Two patients were treated for asymptomatic aneurysms of the inferior mesenteric artery during reconstructive operation for infrarenal aortic disease. These lesions were discovered incidentally during arteriographic study in one case and during operation in the second case. Including these two patients, the number of r...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1985-02-01 00:00:00
abstract:BACKGROUND:Intravenous (IV) fluid therapy should be individualized according to each patient's weight, disease, and comorbidities, as well as the type and duration of the operative procedure. Laparoscopic cholecystectomy represents one of the most common, short-duration operations; thus, the aim of this study was to as...
journal_title:Surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.surg.2017.10.030
更新日期:2018-04-01 00:00:00
abstract::Severe abdominal pain was the major indication for operation in 85 patients with chronic pancreatitis. Preoperative endoscopic retrograde cholangiopancreatography (50 patients) or intraoperative pancreatic ductograms (44 patients) demonstrated dilated or obstructed major pancreatic ducts in 50 patients (59%), nonvisua...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract::Postendarterectomy platelet deposition and thrombus formation may play an important role not only in vessel wall healing but also in the small incidence of postoperative cerebral ischemia and postoperative stenosis. A study has been performed using a canine model to investigate the healing response to carotid endarter...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1983-03-01 00:00:00
abstract:BACKGROUND:This study was conducted to identify the relevant cutoff value and to evaluate the usefulness of postoperative-stimulated serum thyroglobulin (Tg) at the time of (131)I ablation for the prediction of disease status in patients with differentiated thyroid carcinoma (DTC) who received high-dose (131)I ablation...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2012.12.008
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Lung injury in severe acute pancreatitis is mediated by infiltrating leukocytes. Our laboratory has previously demonstrated that acute lung injury in acute pancreatitis results in an up-regulation of vascular adhesion molecule-1 (VCAM-1) cell surface receptor expression on pulmonary vascular endothelium and ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2003.84
更新日期:2003-02-01 00:00:00
abstract:INTRODUCTION:Propranolol has been shown previously to decrease the mobilization of hematopoietic progenitor cells (HPCs) after acute injury in rodent models; however, this acute injury model does not reflect the prolonged period of critical illness after severe trauma. Using our novel lung contusion/hemorrhagic shock/c...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.06.031
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Aggressive screening for blunt cerebrovascular injury (BCVI) and prompt anticoagulation for documented injuries has resulted in a significant reduction in ischemic neurologic events. An association between vertebral artery injuries (VAIs) and specific cervical spine fracture patterns has been suggested; howe...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2006.04.005
更新日期:2007-01-01 00:00:00
abstract::Percutaneous drainage (PCD) of abdominal infection is a therapeutic modality whose role is not well defined. Surgical literature on abdominal infection cites a cumulative mortality rate in the range of 20% to 30%, markedly dissimilar from the 80% to 90% cure rates reported in the literature on PCD. We reviewed the PCD...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:Because the adhesive glycoprotein von Willebrand Factor (vWF) mediates initial platelet attachment at sites of vascular injury and may also contribute to shear-dependent platelet thrombus formation, we have determined in vivo the relative antithrombotic efficacy and hemostatic safety of infusing murine monoc...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00