Poor Glycaemic Control Is Associated with Increased Lipid Peroxidation and Glutathione Peroxidase Activity in Type 2 Diabetes Patients.

abstract：:The regulation on calcium oxalate (CaOx) crystallization and protective effect on human proximal tubular epithelial cells (HK-2) of four green tea polysaccharides (TPSs) with molecular weights of 10.88 (TPS0), 8.16 (TPS1), 4.82 (TPS2), and 2.3 kDa (TPS3) were comparatively studied. XRD, Fourier transform infrared spec...

journal_title：Oxidative medicine and cellular longevity

authors： Liu H,Sun XY,Wang FX,Ouyang JM

更新日期：2020-05-12 00:00:00

abstract：:Oxidative stress plays a pathological role in the development of various diseases including diabetes, atherosclerosis, or cancer. Systemic oxidative stress results from an imbalance between oxidants derivatives production and antioxidants defenses. Reactive oxygen species (ROS) are generally considered to be detriment...

journal_title：Oxidative medicine and cellular longevity

authors： Le Lay S,Simard G,Martinez MC,Andriantsitohaina R

更新日期：2014-01-01 00:00:00

abstract：:Oxidative stress (OS) is known to be strongly involved in a large number of fetal, neonatal, and adult diseases, including placental disorders, leading to pregnancy loss and stillbirths. A growing body of research links OS to preeclampsia, gestational diabetes, obesity, spontaneous abortion, recurrent pregnancy, prete...

journal_title：Oxidative medicine and cellular longevity

authors： Rudov A,Balduini W,Carloni S,Perrone S,Buonocore G,Albertini MC

更新日期：2014-01-01 00:00:00

abstract：:Cholestatic liver injury, due to obstruction of the biliary tract or genetic defects, is often accompanied by progressive inflammation and liver fibrosis. Methane-rich saline (MRS) has anti-inflammatory properties. However, whether MRS can provide protective effect in cholestatic liver injury is still unclear. In this...

journal_title：Oxidative medicine and cellular longevity

authors： Li Z,Chen D,Jia Y,Feng Y,Wang C,Tong Y,Cui R,Qu K,Liu C,Zhang J

更新日期：2019-11-18 00:00:00

abstract：:The infiltration of red blood cells into atheromatous plaques is implicated in atherogenesis. Inside the lesion, hemoglobin (Hb) is oxidized to ferri- and ferrylHb which exhibit prooxidant and proinflammatory activities. Cystathione gamma-lyase- (CSE-) derived H2S has been suggested to possess various antiatherogenic ...

journal_title：Oxidative medicine and cellular longevity

authors： Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J

更新日期：2018-01-21 00:00:00

abstract：:Fungal immunomodulatory proteins (FIPs) are a class of small proteins that have been extensively studied for their immunomodulatory activities. In this study, two novel FIPs from Lentinus tigrinus were identified and named Fip-lti1 and Fip-lti2. The bioactive characteristics of Fip-lti1 and Fip-lti2 were compared to a...

journal_title：Oxidative medicine and cellular longevity

authors： Gao Y,Wáng Y,Wāng Y,Wu Y,Chen H,Yang R,Bao D

更新日期：2019-05-06 00:00:00

abstract：:Oxidative stress is involved in pathophysiology and pathological conditions of numerous human diseases. Thus, understanding the mechanisms underlying the redox homeostasis in cells and organs is valuable for discovery of therapeutic drugs for oxidative stress-related diseases. Recently, by applying chemical biology ap...

journal_title：Oxidative medicine and cellular longevity

authors： Yukitake H,Takizawa M,Kimura H

更新日期：2017-01-01 00:00:00

abstract：:Hippocampal neurogenesis is changed by brain injury. When neuroinflammation accompanies injury, activation of resident microglial cells promotes the release of inflammatory cytokines and reactive oxygen/nitrogen species like nitric oxide (NO). In these conditions, NO promotes proliferation of neural stem cells (NSC) i...

journal_title：Oxidative medicine and cellular longevity

authors： Carreira BP,Santos DF,Santos AI,Carvalho CM,Araújo IM

更新日期：2015-01-01 00:00:00

abstract：:The neuroendocrine functions of the pineal affect a wide variety of glandular and nervous system processes. Beside melatonin (MEL), the pineal gland secretes and expresses certain proteins essential for various physiological functions. It has been suggested that the pineal gland may also have an antioxidant role due t...

journal_title：Oxidative medicine and cellular longevity

authors： Bharti VK,Srivastava RS

更新日期：2009-04-01 00:00:00

abstract：:Metabolic diseases, such as insulin resistance, type II diabetes, and obesity, are associated with a low-grade chronic inflammation (inflammatory stress), oxidative stress, and endoplasmic reticulum (ER) stress. Because the integration of these stresses is critical to the pathogenesis of metabolic diseases, agents and...

journal_title：Oxidative medicine and cellular longevity

authors： Son Y,Lee JH,Chung HT,Pae HO

更新日期：2013-01-01 00:00:00

abstract：:Type 2 diabetes (T2DM) and its complications constitute a major worldwide public health problem, with high rates of morbidity and mortality. Biomarkers for predicting the occurrence and development of the disease may therefore offer benefits in terms of early diagnosis and intervention. This review provides an overvie...

journal_title：Oxidative medicine and cellular longevity

authors： Bigagli E,Lodovici M

更新日期：2019-05-12 00:00:00

abstract：:Hypoxia, as one of the severe cellular stresses, can cause cellular injury and even cell death. Apoptosis is the main mechanism of regulating cell death and is closely related to the cell death caused by hypoxia. However, hypoxia-induced apoptosis is not entirely the result of direct hypoxic stimulus of cells. In rece...

journal_title：Oxidative medicine and cellular longevity

authors： Guo Y,Tan J,Miao Y,Sun Z,Zhang Q

更新日期：2019-04-17 00:00:00

abstract：:Methionine sulfoxide reductase B1 (MsrB1) is a member of the selenoprotein family, which contributes to the reduction of methionine sulfoxides produced from reactive oxygen species (ROS) by redox processes in energy pathways. However, few studies have examined the role of MsrB1 in human hepatocellular carcinoma (HCC)....

journal_title：Oxidative medicine and cellular longevity

authors： He Q,Li H,Meng F,Sun X,Feng X,Chen J,Li L,Liu J

更新日期：2018-05-10 00:00:00

abstract：:Transient receptor potential vanilloid 1 (TRPV1) is a Ca+2-permeable channel expressed on neuronal and nonneuronal cells, known as an oxidative stress sensor. It plays a protective role in bacterial infection, and recent findings indicate that this receptor modulates monocyte populations in mice with malaria; however,...

journal_title：Oxidative medicine and cellular longevity

authors： Pereira DMS,Teixeira SA,Murillo O,Peixoto EPM,Araújo MC,Sousa NCF,Monteiro-Neto V,Calixto JB,Cunha TM,Marinho CRF,Muscará MN,Fernandes ES

更新日期：2019-05-16 00:00:00

abstract：:Mitochondrial dysfunctions caused by oxidative stress are currently regarded as the main cause of aging. Accumulation of mutations and deletions of mtDNA is a hallmark of aging. So far, however, there is no evidence that most studied oxygen radicals are directly responsible for mutations of mtDNA. Oxidative damages to...

journal_title：Oxidative medicine and cellular longevity

authors： Panov AV,Dikalov SI

更新日期：2020-09-08 00:00:00

abstract：:In recent years, metabolomics analyses have been widely applied to cerebral ischemia research. This paper introduces the latest proceedings of metabolomics research on cerebral ischemia. The main techniques, models, animals, and biomarkers of cerebral ischemia will be discussed. With analysis help from the MBRole webs...

journal_title：Oxidative medicine and cellular longevity

authors： Liu M,Tang L,Liu X,Fang J,Zhan H,Wu H,Yang H

更新日期：2016-01-01 00:00:00

abstract：:Despite tea increased plasma nonenzymatic antioxidant capacity, the European Food Safety Administration (EFSA) denied claims related to tea and its protection from oxidative damage. Furthermore, the Supplement Information Expert Committee (DSI EC) expressed some doubts on the safety of green tea extract (GTE). We perf...

journal_title：Oxidative medicine and cellular longevity

authors： Peluso I,Manafikhi H,Raguzzini A,Longhitano Y,Reggi R,Zanza C,Palmery M

更新日期：2016-01-01 00:00:00

abstract：:Skin diseases associated with inflammation or oxidative stress represent the most common problem in dermatology. The present study demonstrates that fish scale collagen peptides (FSCP) protect against CoCl2-induced cytotoxicity and TNF-α-induced inflammatory responses in human HaCaT keratinocyte cells. Our study is th...

journal_title：Oxidative medicine and cellular longevity

authors： Subhan F,Kang HY,Lim Y,Ikram M,Baek SY,Jin S,Jeong YH,Kwak JY,Yoon S

更新日期：2017-01-01 00:00:00

abstract：:Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of genes necessary to circumvent to hypoxic (low oxygen level) environments. In carcinogenesis, HIFs play a critical role. Indeed, HIF-1α has been validated as a promising target for novel cancer therapeutics, even as clinical i...

journal_title：Oxidative medicine and cellular longevity

authors： Akanji MA,Rotimi D,Adeyemi OS

更新日期：2019-08-14 00:00:00

abstract：:In chronic heart failure (HF), some parameters of oxidative stress are correlated with disease severity. The aim of this study was to evaluate the importance of oxidative stress biomarkers in prognostic risk stratification (death and combined endpoint: heart transplantation or death). In 774 patients, aged 48-59 years...

journal_title：Oxidative medicine and cellular longevity

authors： Romuk E,Wojciechowska C,Jacheć W,Zemła-Woszek A,Momot A,Buczkowska M,Rozentryt P

更新日期：2019-10-09 00:00:00

abstract：:Benzene is a chemical contaminant widespread in industrial and living environments. The oxidative metabolites of benzene induce toxicity involving oxidative damage. Protecting cells and cell membranes from oxidative damage, glucose-6-phosphate dehydrogenase (G6PD) maintains the reduced state of glutathione (GSH). This...

journal_title：Oxidative medicine and cellular longevity

authors： Zhang J,Cao M,Yang W,Sun F,Xu C,Yin L,Pu Y

更新日期：2016-01-01 00:00:00

abstract：:To evaluate RNA oxidation in the early stage of diabetic nephropathy, we applied an accurate method based on isotope dilution high-performance liquid chromatography-triple quadruple mass spectrometry to analyze the oxidatively generated guanine nucleosides in renal tissue and urine from db/db mice of different ages. W...

journal_title：Oxidative medicine and cellular longevity

authors： Wang WX,Luo SB,Jiang P,Xia MM,Hei AL,Mao YH,Li CB,Hu GX,Cai JP

更新日期：2017-01-01 00:00:00

abstract：:The purpose of this study was to investigate the modulation of histone deacetylase 2 (HDAC2) on mitochondrial apoptosis in acute liver failure (ALF). The cellular model was established with LO2 cells stimulated by tumor necrosis factor alpha (TNF-α)/D-galactosamine (D-gal). Rats were administrated by lipopolysaccharid...

journal_title：Oxidative medicine and cellular longevity

authors： Wang Y,Yang F,Jiao FZ,Chen Q,Zhang WB,Wang LW,Gong ZJ

更新日期：2019-04-28 00:00:00

abstract：:Traumatic brain injury (TBI) represents one of the major causes of mortality and disability in the world. TBI is characterized by primary damage resulting from the mechanical forces applied to the head as a direct result of the trauma and by the subsequent secondary injury due to a complex cascade of biochemical event...

journal_title：Oxidative medicine and cellular longevity

authors： Angeloni C,Prata C,Dalla Sega FV,Piperno R,Hrelia S

更新日期：2015-01-01 00:00:00

abstract：:Stroke is a leading cause of mortality worldwide, as well as a source of long-term disabilities and huge socioeconomic costs. This study investigates the effects of resveratrol, an antioxidant supplement, on blood pressure, weight status, glucose, and lipid profile in patients who had a stroke in the last 12 months. T...

journal_title：Oxidative medicine and cellular longevity

authors： Fodor K,Tit DM,Pasca B,Bustea C,Uivarosan D,Endres L,Iovan C,Abdel-Daim MM,Bungau S

更新日期：2018-03-18 00:00:00

abstract：:Aging leads to a number of disadvantageous changes in the cardiovascular system. Deterioration of vascular homoeostasis with increase in oxidative stress, chronic low-grade inflammation, and impaired nitric oxide bioavailability results in endothelial dysfunction, increased vascular stiffness, and compromised arterial...

journal_title：Oxidative medicine and cellular longevity

authors： Rammos C,Totzeck M,Deenen R,Köhrer K,Kelm M,Rassaf T,Hendgen-Cotta UB

更新日期：2015-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive neurodegeneration. Pathogenetic mechanisms, triggered by β-amyloid (Aβ) accumulation, include oxidative stress, derived from energy homeostasis deregulation and involving mitochondria and peroxisomes. We here addressed the oxida...

journal_title：Oxidative medicine and cellular longevity

authors： Porcellotti S,Fanelli F,Fracassi A,Sepe S,Cecconi F,Bernardi C,Cimini A,Cerù MP,Moreno S

更新日期：2015-01-01 00:00:00

abstract：:Vascular endothelial dysfunction is associated with increased mortality in patients with diabetes. Astragaloside IV (As-IV) is a bioactive saponin with therapeutic potential as an anti-inflammatory and antiendothelial dysfunction. However, the underlying mechanism for how As-IV ameliorated endothelial dysfunction is s...

journal_title：Oxidative medicine and cellular longevity

authors： Leng B,Li C,Sun Y,Zhao K,Zhang L,Lu ML,Wang HX

更新日期：2020-09-14 00:00:00

abstract：:The cystine/glutamate exchanger (system xc (-)) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, system xc (-) can potentially cause excitotoxicity. However, through providing cystine to the cell, it regulates the levels of cellular glutathione (GSH), the main endogeno...

journal_title：Oxidative medicine and cellular longevity

authors： Albano R,Raddatz NJ,Hjelmhaug J,Baker DA,Lobner D

更新日期：2015-01-01 00:00:00

abstract：:Deficiency of nitric oxide (NO) and oxidative stress can be a cause, a consequence, or, more often, a potentiating factor for hypertension and hypertensive renal disease. Both NO and superoxide anions are radical molecules that interact with each other, leading to oxidative damage of such organs as the kidney. In the ...

journal_title：Oxidative medicine and cellular longevity

authors： Majzunova M,Kvandova M,Berenyiova A,Balis P,Dovinova I,Cacanyiova S

更新日期：2019-11-22 00:00:00