Repeat Resection and Intraoperative Radiotherapy for Malignant Gliomas of the Brain: A History and Review of Current Techniques.

Abstract:

:The degree of primary resection of malignant brain gliomas (MBGs) has correlated positively with progression-free and overall survival. The indications for surgery and reoperation in MBG relapse remain controversial. Surgery will not be curative and should be followed by adjuvant treatment. We reviewed the reported studies with respect to repeat resection and the various methods of intraoperative radiotherapy for MBGs from the initial experience with high-energy linear accelerators in Japan to modern, integrated brachytherapy solutions using solid and balloon applicators. Because of the findings from our review, we have begun to research into the use of intraoperative balloon brachytherapy for recurrent MBGs.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Krivoshapkin A,Gaytan A,Salim N,Abdullaev O,Sergeev G,Marmazeev I,Cesnulis E,Killeen T

doi

10.1016/j.wneu.2019.09.037

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

356-362

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(19)32467-2

journal_volume

132

pub_type

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