Abstract:
BACKGROUND:Primary intracranial sarcomas of the central nervous system are rare tumors. They mainly arise from intracranial mesenchymal tissue present in the meninges and can occur at any age. Sometimes osteosarcoma can involve the skull rather than long body bones. In this latter case it is the more common subtype. Surgery, when possible, is a mandatory option often associated with radiation therapy (RT) and chemotherapy. Brain radionecrosis (BRN) is commonly observed due to the growing use of radiosurgery and higher cumulative doses of radiation therapy. The combination of perfusion magnetic resonance imaging and 18fluoro-deoxy-glucose positron emission tomography can help to differentiate tumor progression from radiation injury. Steroids, anticoagulants, and bevacizumab usually control BRN. However, BRN can also have an unfavorable course. CASE DESCRIPTION:Here, we present a case of a 60-year-old male who underwent surgery for a brain tumor. The examination showed a primary undifferentiated high-grade sarcoma. Adjuvant RT was given with a total dose of 60 Gy. Six months later, the patient underwent a second surgery that revealed a BRN progressing despite different pharmacologic attempts. CONCLUSIONS:Primary intracranial sarcomas of the central nervous system are less prevalent among older adults with respect to the younger population. The use of RT alone or combined with chemotherapy is aimed at prolonging survival. However, it is not clearly defined if adjuvant treatments affect this parameter in older patients. RT should be carefully discussed owing to its potential severe neurologic toxicity. Indeed, a BRN can have a significant impact on quality of life and lead to death in certain cases.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Napolitano M,Ranieri A,Maniscalco GT,Riccardi F,De Dominicis G,Caiazzo Pdoi
10.1016/j.wneu.2020.07.174subject
Has Abstractpub_date
2020-11-01 00:00:00pages
285-288eissn
1878-8750issn
1878-8769pii
S1878-8750(20)31696-Xjournal_volume
143pub_type
abstract:BACKGROUND:Cervical sagittal alignment parameters are essential to plan stages of surgery. The aims of this study were to evaluate the relationship between cervical sagittal alignment parameters and surgical outcomes after anterior cervical arthrodesis; to identify parameters linked to a better outcome; to determine th...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.09.110
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:In the management of meningiomas invading the major venous sinuses, balance between tumor control and complication prevention is desirable. The aim of this study was to describe an institutional experience in management of meningiomas involving major venous sinuses. METHODS:A retrospective study was carried...
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abstract::This report portrays our pitfall in the initial diagnosis of an intracranial arterial dissection that we misinterpreted as a saccular aneurysm. Intracranial arterial dissections presenting with convexity subarachnoid hemorrhage are rare, thus being easily mistaken with mild traumatic head injuries and therefore preven...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.11.145
更新日期:2017-02-01 00:00:00
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journal_title:World neurosurgery
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doi:10.1016/j.wneu.2018.09.132
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journal_title:World neurosurgery
pub_type: 杂志文章,评审
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doi:10.1016/j.wneu.2017.07.143
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doi:10.1016/j.wneu.2020.08.150
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journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2019.05.003
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journal_title:World neurosurgery
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doi:10.1016/j.wneu.2020.06.013
更新日期:2020-09-01 00:00:00
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journal_title:World neurosurgery
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doi:10.1016/j.wneu.2019.09.125
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abstract:BACKGROUND:The biopsy is recognized as the most accurate method to determine the histologic characterization of sellar germ cell tumors. It is difficult to evaluate the prognosis before histologic confirmation. OBJECTIVE:This study aimed to evaluate the independent prognostic risk factors of patients with sellar germ ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.01.028
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:After subarachnoid hemorrhage (SAH), headache management is often difficult owing to the need to use multiple analgesic drugs. Fentanyl is an opioid we can use after surgery, and it can decrease pain post SAH. The aim of this study was to investigate the effectiveness and safety of fentanyl for management of...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.10.062
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Large calcified intrasellar masses, called pituitary stones, have been reported as calcified pituitary adenomas in the literature. Although relatively rare, calcified pituitary adenomas appear in various formations. Thus, whether the lesion is removable-and, if so, which approach is appropriate-mainly depend...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2018.11.255
更新日期:2019-03-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.09.100
更新日期:2021-01-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.03.101
更新日期:2017-07-01 00:00:00
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journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2018.01.100
更新日期:2018-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.wneu.2017.07.013
更新日期:2017-10-01 00:00:00
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journal_title:World neurosurgery
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doi:10.1016/j.wneu.2018.08.097
更新日期:2018-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.wneu.2018.03.148
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journal_title:World neurosurgery
pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.wneu.2017.10.004
更新日期:2018-01-01 00:00:00
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doi:10.1016/j.wneu.2017.11.094
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更新日期:2019-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-11-27 00:00:00
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更新日期:2020-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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更新日期:2015-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-11-01 00:00:00