Abstract：
OBJECTIVE:To observe effects of rosiglitazone (RSG) infusion therapy on perihematomal peroxisome-proliferator-activated receptor gamma (PPARγ), glutamate, blood-brain barrier (BBB) permeability, and brain edema. METHODS:Fifty male rabbits (2.8-3.4 kg) were randomly assigned to a normal control (NC) group, model control (MC) group, RSG group, minimally invasive surgery (MIS) group, or MIS and RSG (MIS+RSG) group. Intracranial hemorrhage was induced in all rabbits except for the NC group. MIS procedures were performed to evacuate the intracranial hemorrhage 6 hours after the intracranial hemorrhage model was prepared successfully. The animals were sacrificed on day 7, and the perihematomal brain tissue was obtained to determine PPARγ, glutamate, and BBB permeability. RESULTS:Compared with the MC group, the MIS group displayed a remarkable decrease in PPARγ, glutamate, and BBB permeability. The RSG group showed similar results in glutamate level and BBB permeability but a significant increase in PPARγ. The MIS+RSG group displayed an increase in PPARγ and a more significant decrease in glutamate, BBB permeability, and neurologicl deficit scores compared with the other groups. CONCLUSIONS:Performing MIS followed by RSG infusion therapy might increase PPARγ expression and might be more efficacious for reducing glutamate level and BBB permeability and improving neurologic function than MIS or RSG therapy used alone.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Wu G,Jiao Y,Wu J,Ren S,Wang L,Tang Z,Zhou Hdoi
10.1016/j.wneu.2017.11.145subject
Has Abstractpub_date
2018-03-01 00:00:00pages
e40-e46eissn
1878-8750issn
1878-8769pii
S1878-8750(17)32077-6journal_volume
111pub_type
杂志文章abstract：BACKGROUND:This study sought to describe a patient with a slowly progressive cauda equina syndrome (CES) who had imaging findings of the CES that occurs as a rare complication of ankylosing spondylitis (AS), but whose spinal fusion was due to thoracolumbosacral instrumentation, not spondyloarthropathy. METHODS:A 53-ye...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2011.12.014
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Focal cortical dysplasias (FCDs) are highly epileptogenic and frequently associated with medically refractory focal epilepsy. FCDs are frequently located in the frontal lobe, making its complete resection highly challenging when in proximity to the motor cortex. CASE DESCRIPTION:We report a case of a 25-yea...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.08.181
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Arachnoiditis ossificans (AO) is a rare entity characterized by the presence of calcified plaques formed by the metaplasia of arachnoid cells. Over 50 cases of AO have been reported, with predisposing factors including spinal trauma, hemorrhage, vascular abnormalities, and infection. The administration of oi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.178
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:The treatment of giant olfactory groove meningiomas (OGMs; maximum diameter ≥ 6 cm) poses special problems and represents a surgical challenge. We discuss the long-term results in a series of 18 patients with giant OGMs and report our experience on a global strategy encompassing the pterional approach to mana...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2011.03.021
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Glioblastoma multiforme (GBM) is a rapid-growing central nervous system neoplasm. We report a case of GBM with extensive intramedullary lumbar drop metastasis and highly unusual osseous spine metastasis from a primary infratentorial GBM occurring 10 years after the initial diagnosis, which to our knowledge h...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.07.142
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Severe complications after reperfusion therapy for acute major vessel occlusion are not well described. We present an extremely rare case of a patient with rapid malignant brain swelling subacutely after acute ischemic stroke. CASE DESCRIPTION:An 84-year-old man underwent reperfusion therapy for acute left ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.151
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Lumbar arthrodesis is a surgical option for treatment of lumbar pathologies. Stability of the spinal construct partly depends on load-bearing support from back muscles. Despite the role of the psoas muscle in upright spinal stabilization, data describing its clinical significance are scarce. We evaluated the...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.11.022
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Spontaneous resolution of acute subdural hematomas (SDHs), occurring as the result of a traumatic injury, is well reported in the literature and rapidly resolving SDHs have been reported as well. Although the mechanism behind the rapid resolution of a SDH has not been well understood, there are postulated me...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.029
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Stent retrievers (SRs) can be used to perform mechanical thrombectomy for the treatment of acute major arterial occlusion. Recanalization is faster, and outcomes are better with treatment involving these devices than with internal treatment. Although several SRs are available, their clot-capturing abilities ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.09.106
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:This meta-analysis of published randomized controlled trials (RCTs) aimed to investigate the efficacy and safety of endovascular therapy (ET) for patients with acute ischemic stroke. METHODS:The summary relative risks (RRs) with corresponding 95% confidence intervals were calculated to measure the effectiven...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.07.156
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:This study sought to show and analyze the main authors' experience (P.R. and J.M.C.) in previously coiled aneurysm surgery as an emerging challenge in today's neurosurgical practice. METHODS:Twelve female and 8 male patients, whose ages ranged from 32 to 56 years (average 43.5), underwent surgery between Apr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2013.09.016
更新日期：2014-07-01 00:00:00
abstract：:In rare instances, extradural internal carotid artery aneurysms can present with massive epistaxis, which is often a fatal event. We present the case of a young female with an aneurysm eroding through the sphenoid sinus and whose timely diagnosis resulted in treatment of the aneurysm with coil embolization and satisfa...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.09.006
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION:Although the indication of endoscopic approaches for anterior skull base meningiomas (ASBM) has been progressively refined, there remains a paucity of data on recurrence rates after resection. To analyze and compare recurrence rates of ASBM resected through endoscopic endonasal (EEE) versus transcranial (T...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.210
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:This is an original report describing the long-term follow-up outcome of a cranioplasty. A large calvarial bone defect of a child was reconstructed with a bioactive and biostable non-metallic implant. CASE DESCRIPTION:This is a case study of a young child with an infantile fibrosarcoma of occipital bone. Th...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.01.028
更新日期：2019-01-23 00:00:00
abstract：BACKGROUND:For more than 2 decades, dural spinal cysts have been broadly classified as extradural and intradural. CASE DESCRIPTION:A 40-year-old woman presented with radicular thoracic pain. Intraoperative findings showed the cyst to be present within the dura itself. CONCLUSIONS:We suggest a revised classification o...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.11.051
更新日期：2016-04-01 00:00:00
abstract：INTRODUCTION:Evidence regarding whether the polyaxial pedicle screws at the upper instrumented vertebrae (UIV) are superior to monoaxial pedicle screws in prevention of proximal junctional kyphosis (PJK) is not clear. The aim of this study was therefore to explore the influence of different types of pedicle screws at U...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.02.013
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Cervical laminectomy has 2 major disadvantages: postlaminectomy adhesion of dural membrane and lack of a fusion bed. The objective of this study was to determine whether simultaneous cervical laminoplasty with fusion (CLPF) might overcome these unwanted outcomes. METHODS:Patients who underwent CLPF for trea...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.01.018
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:Intraoperative use of positive end-expiratory pressure (PEEP) has a protective effect in patients with acute lung injury and is recommended during anesthesia to minimize postoperative pulmonary complications. However, high levels of pressure might also cause harm to the lung because of overdistension. This r...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.12.014
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Altered mental status (AMS) has been associated with inferior surgical outcomes. The factors leading to AMS after spine surgery are unknown. The aim of this study is to determine the risk factors and independent predictors of 30-day readmission for AMS in patients with spine deformity after undergoing electi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.02.001
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVE:To describe percutaneous balloon compression (PBC) of the trigeminal rootlets as treatment for trigeminal neuralgia (TN), including history, operative techniques, outcomes, side effects, and some recent findings increasing the likelihood of a positive outcome. METHODS:PBC is indicated in patients with TN in ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2012.03.014
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVE:To describe epidemiology in relation to gender differences and treatment modalities 10 years after intracranial aneurysm rupture in the Stockholm cohort 1996-1999. METHODS:A total of 468 consecutive patients with aneurysmal subarachnoid hemorrhage were followed-up in a retrospective cohort design 10 years af...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2012.06.041
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Complete aneurysm obliteration is the goal of aneurysm treatment. In selected cases, a neck remnant may be left to preserve a critical branch. Literature on ophthalmic artery sacrifice in the treatment of cerebral aneurysms and subsequent risk of vision loss is limited. CASE DESCRIPTION:Herein, we describe ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.04.196
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Cervical sagittal alignment parameters are essential to plan stages of surgery. The aims of this study were to evaluate the relationship between cervical sagittal alignment parameters and surgical outcomes after anterior cervical arthrodesis; to identify parameters linked to a better outcome; to determine th...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.09.110
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:The rationale of only fixation without any kind of bone, ligament, disc, or osteophyte decompression as a treatment for single- or multiple-level cervical spinal degeneration was analyzed. The concept was based on the understanding that muscle weakness-related spinal instability is the cause of spinal degene...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.03.104
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Spontaneous regression in intracranial germ cell tumors (GCTs) is an extremely rare phenomenon with only 9 cases reported. The mechanism and natural history of this phenomenon are still equivocal. METHODS:A 12-year-old boy presented with a lesion in the suprasellar region with involvement of basal ganglia a...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.06.220
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:The optimal management of dural closure is unclear; therefore, we aimed to survey current common practices among Italian practitioners. METHODS:The Delphi method was used to achieve a consensus on dura mater closing techniques in Italy. A steering committee decided 3 major topics to be investigated: pre- and...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.125
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Extreme lateral interbody fusion (ELIF) is a powerful tool for interbody fusion and coronal deformity correction. However, evidence regarding the success of ELIF in decompressing foraminal, lateral recess, and central canal stenosis is lacking. We performed a systematic review of current literature on the po...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2017.01.080
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVE:Spinal dural arteriovenous fistulas (SDAVFs) are rare vascular spinal malformations. According to the reported data, surgery seems to result in better occlusion rates than endovascular treatment. However, the post-treatment evolution of neurological symptoms stratified by the treatment remains unknown. The ma...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.04.005
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:A neuroendoscopic biopsy has become common for the diagnosis of ventricular tumors. However, its utility in patients with germ cell tumors (GCTs) has not been well discussed. We examined the usefulness and pitfalls of neuroendoscopic biopsies of intraventricular GCTs at a single institution. METHODS:We retro...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.07.013
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:To report new results with ethylene oxide sterilization and new experiences with autogenous bone flaps autoclaved at a high or low temperature for preservation of a bone flap after decompressive craniectomy. METHODS:In 45 patients who underwent a decompressive craniectomy, we determined bone flap preservatio...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.03.042
更新日期：2016-06-01 00:00:00
