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Outcome of patients with human immunodeficiency virus on maintenance hemodialysis.

Abstract：

:Fifty-one adults with HIV infection, including 20 chronic hemodialysis patients with superimposed HIV infection and 31 patients with HIV-associated nephropathy requiring chronic maintenance hemodialysis were followed to evaluate survival on outpatient dialysis in relation to the clinical stage of the HIV infection. Regardless of when they contracted the infection, AIDS patients who required maintenance hemodialysis had a poor prognosis. All 17 patients who developed AIDS died after a mean of 93 +/- 32 days on hemodialysis (median 30 days; range 2 to 540 days). On the other hand, 12 asymptomatic HIV carriers were alive after a mean follow-up on chronic hemodialysis of 488 +/- 75 days (median 420 days; range 142 to 850 days); and five hemodialyzed patients with ARC were alive after 564 +/- 191 days (median 420 days; range 150 to 1230 days). The data confirm the lack of effectiveness of maintenance hemodialysis for prolonging life in patients with AIDS. This dismal prognosis was evident whether renal failure antedated HIV infection or whether it was HIV-associated. In asymptomatic HIV carriers and in patients with ARC, however, maintenance hemodialysis provides meaningful, long-term life support.

journal_name

Kidney Int

journal_title

Kidney international

authors

Ortiz C,Meneses R,Jaffe D,Fernandez JA,Perez G,Bourgoignie JJ

doi

10.1038/ki.1988.172

subject

Has Abstract

pub_date

1988-08-01 00:00:00

pages

248-53

issue

2

eissn

0085-2538

issn

1523-1755

pii

S0085-2538(15)34345-3

journal_volume

34

pub_type

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