Effects of Electrical Stimulation on Stem Cells.

abstract：:Applications of regenerative medicine technology may offer new therapies for patients with injuries, end-stage organ failure, or other clinical problems. Currently, patients suffering from diseased and injured organs can be treated with transplanted organs. However, there is a shortage of donor organs that is worsenin...

journal_title：Current stem cell research & therapy

authors： Atala A

更新日期：2008-01-01 00:00:00

abstract：:Intervertebral disc (IVD) degeneration is one of the leading causes of low back pain, which affects a large proportion of the global population at a huge socioeconomic burden. Current treatments focus primarily on symptomatic pain relief or surgery, but offer relatively poor long-term efficacy as they fail to address ...

journal_title：Current stem cell research & therapy

authors： Clarke LE,Richardson SM,Hoyland JA

更新日期：2015-01-01 00:00:00

abstract：:The intestinal mucosa has an amazing regenerative capacity, enabling rapid restoration of its physiological functions following injury. The ability to do this resides with the epithelial stem cells located within glandular invaginations in the mucosal surface. Recent advances toward the isolation and characterization ...

journal_title：Current stem cell research & therapy

authors： Day RM

更新日期：2006-01-01 00:00:00

abstract：:Pluripotent stem cells (PSCs) derived from somatic cells represent a powerful experimental tool for investigating the molecular mechanisms underlying the disease phenotype; with prospects to advance medical therapies. They also have significant potential as a renewable source of autologous cells for cellular therapy. ...

journal_title：Current stem cell research & therapy

authors： Alateeq S,Fortuna PR,Wolvetang E

更新日期：2015-01-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the selective loss of both spinal and upper motor neurons. One strategy in treating ALS is to use stem cells to replace lost spinal motor neurons. However, transplanted stem cell-derived motor neurons may not survive when exposed to the harsh...

journal_title：Current stem cell research & therapy

authors： Thonhoff JR,Ojeda L,Wu P

更新日期：2009-09-01 00:00:00

abstract：AIMS:A systematic review and meta-analysis were performed to explore the clinical outcome of the transplantation of stem cells from various human tissue sources in cirrhotic patients. METHODS:The relevant papers were searched via PubMed, EMBASE, and Cochrane Library databases. Changes in liver function before and afte...

journal_title：Current stem cell research & therapy

authors： Qi X,Guo X,Su C

更新日期：2015-01-01 00:00:00

abstract：: ...

journal_title：Current stem cell research & therapy

authors： Yoo JJ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Autoimmune disease is a refractory disease. Accumulating Evidence has revealed that the manipulation of mesenchymal stem cells may have the potential to control or even treat autoimmune diseases. Human gingiva-derived mesenchymal stem cells (GMSCs) are emerging as a new line of mesenchymal stem cells that ha...

journal_title：Current stem cell research & therapy

authors： Huang F,Liu ZM,Zheng SG

更新日期：2018-01-01 00:00:00

abstract：:Chronic myeloproliferative disorders (cMPDs) are clonal hemopoietic malignancies arising at the multipotent stem cell level. These conditions are characterized by increased blood count, marrow hyperplasia and extramedulary hemopoiesis. Vascular events might complicate their course, and transformation to either acute l...

journal_title：Current stem cell research & therapy

authors： Spanoudakis E,Tsatalas C

更新日期：2009-05-01 00:00:00

abstract：:Stroke is the second most common cause of death and the leading cause of disability in the world. About 30% of the people that are affected by stroke die within a year; 25% of the patients that survive stroke remain in need of care after a year. Therefore, stroke is a major burden for health care costs. The most commo...

journal_title：Current stem cell research & therapy

authors： Zents K,Copray S

更新日期：2016-01-01 00:00:00

abstract：:Haematopoietic stem cell transplantation (HSCT) is a curative treatment of many hematological disorders. However, although significant advances have been made in donor-recipient matching or conditioning regimens, HSCT is associated with a risk of post transplant complications. Those include generation of toxic lesions...

journal_title：Current stem cell research & therapy

authors： Bogunia-Kubik K,Wysoczanska B,Lange A

更新日期：2006-05-01 00:00:00

abstract：:The pressing demand to elucidate the biology of human embryonic stem (ES) cells and to realize their therapeutic potential has greatly promoted the progresses in the optimization of the culture systems used for this highly promising cell type. These progresses include the characterization of exogenous regulators of pl...

journal_title：Current stem cell research & therapy

authors： Lin G,Xu RH

更新日期：2010-09-01 00:00:00

abstract：:Stem/progenitor cells for cell therapy and regenerative medicine should ideally be available in large numbers, after having been isolated using minimally invasive or non-invasive methodologies. Also, they should exhibit wide differentiation potential into multiple lineages, as well as capability to be used successfull...

journal_title：Current stem cell research & therapy

authors： Eiro N,Fraile M,Schneider J,Vizoso FJ

更新日期：2018-01-01 00:00:00

abstract：:Postnatal skeletogenesis is a highly regulated process that subpopulations of bone marrow stem cells differentiate into mature skeletal tissues to maintain and repair the postnatal skeletons. Based on their skeletogenic capacity, purified bone marrow stem cells have been used to repair and replace damaged skeletal tis...

journal_title：Current stem cell research & therapy

authors： Deng P,Xu X,Chen Q

更新日期：2015-01-01 00:00:00

abstract：:Adipose-derived stem cells are adult stem cells which are easy to obtain and multi-potent. Stem-cell therapy has become a promising new treatment for many diseases, and plays an increasingly important role in the field of tissue repair, regeneration and reconstruction. The physicochemical properties of the extracellul...

journal_title：Current stem cell research & therapy

authors： Wang L,Li Y,Zhang M,Huang K,Peng S,Xiao J

更新日期：2021-01-01 00:00:00

abstract：:Human mesenchymal stem cells (hMSCs) are multipotent non-hematopoietic precursor cells with the ability to differentiate into several tissue types. The use of hMSCs has gained significant importance in cancer therapies as well as a large number of degenerative disease therapies due to their homing abilities. However, ...

journal_title：Current stem cell research & therapy

authors： Serakinci N,Kalkan R,Tulay P

更新日期：2016-01-01 00:00:00

abstract：:Telomeres are the protective end caps of eukaryotic chromosomes and they decide the proliferative lifespan of somatic cells, as the guardians of the cell replication. Telomere length in leucocytes reflects telomere length in other somatic cells. Leucocyte telomere length can be a biomarker of human ageing. The risk of...

journal_title：Current stem cell research & therapy

authors： Celtikci B,Erkmen GK,Dikmen ZG

更新日期：2020-04-21 00:00:00

abstract：:Osteoarthritis (OA) is the most common degenerative joint disorder worldwide. OA represents an increasing threat to the quality of life of affected persons as well as for health resources expenditure. The incapability of cartilage to heal has been long time regarded as the major cause of progressive joint degeneration...

journal_title：Current stem cell research & therapy

authors： Labusca L,Mashayekhi K

更新日期：2015-01-01 00:00:00

abstract：:Defects in articular cartilage injury and chronic osteoarthritis are very widespread and common, and the ability of injured cartilage to repair itself is limited. Stem cell-based cartilage tissue engineering provides a promising therapeutic option for articular cartilage damage. However, the application of the techniq...

journal_title：Current stem cell research & therapy

authors： Chen Y,Ouyang X,Wu Y,Guo S,Xie Y,Wang G

更新日期：2020-01-01 00:00:00

abstract：:The liver is a vital organ for life and the only internal organ that is capable of natural regeneration. Although the liver has high regeneration capacity, excessive hepatocyte death can lead to liver failure. Various factors can lead to liver damage including drug abuse, some natural products, alcohol, hepatitis, and...

journal_title：Current stem cell research & therapy

authors： Anwar I,Ashfaq UA,Shokat Z

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Today, coronary artery disease is still one of the most important causes of mortality despite advanced surgical methods, pharmacotherapies and organ transplantation. These treatment modalities are intended to prevent further progression of myocardial infarction and do not involve the repair of the damaged pa...

journal_title：Current stem cell research & therapy

authors： Aslan A,Allahverdiyev AM,Bagirova M,Abamor ES

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Periodontitis is a multifactorial infectious disease that affects a large population worldwide. Oral microorganisms and susceptible host have been proposed to be the prerequisite for the development of periodontitis. Recently, the involvement of epigenetic modifications in the development of periodontitis ha...

journal_title：Current stem cell research & therapy

authors： Luo Y,Peng X,Duan D,Liu C,Xu X,Zhou X

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Cellular differentiation occurs in a complicated microenvironment containing multiple components including soluble factors and physical cues. In addition to biochemical composition, physical cues are also crucial in determining cellular behaviors. OBJECTIVE:To better understand the interaction between physi...

journal_title：Current stem cell research & therapy

authors： Zhang Q,Lin S,Liao J,Cai X

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Retinitis pigmentosa (RP), an inherited disease characterized by progressive loss of photoreceptors and retinal pigment epithelium, is a leading genetic cause of blindness. Cell transplantation to replace lost photoreceptors is a potential therapeutic strategy, but technical limitations have prevented clin...

journal_title：Current stem cell research & therapy

authors： Peng Y,Zhang Y,Huang B,Luo Y,Zhang M,Li K,Li W,Wen W,Tang S

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Multiple studies have focused on stem cell-based treatments for rotator cuff disorders; however, the outcomes are not consistent. OBJECTIVES:This systematic review and meta-analysis were performed to evaluate the effects of stem cells on rotator cuff healing. METHODS:A detailed search of relevant studies w...

journal_title：Current stem cell research & therapy

authors： Liu F,Meng Q,Yin H,Yan Z

更新日期：2019-01-01 00:00:00

abstract：:The intestine serves mainly as a place for digestion and absorption and functions as an immune and endocrine organ. Intestinal stem cells (ISCs) play critical roles in the maintenance of intestinal homeostasis and regeneration, and a complex of signaling pathways is involved in these processes. The Notch signaling pat...

journal_title：Current stem cell research & therapy

authors： Liang SJ,Li XG,Wang XQ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Articular cartilage defects often result in pain, loss of function and finally osteoarthritis. Developing cell-based therapies for cartilage repair is a major goal of orthopaedic research. Autologous chondrocyte implantation is currently the gold standard cell-based surgical procedure for the treatment of la...

journal_title：Current stem cell research & therapy

authors： Kubosch EJ,Lang G,Furst D,Kubosch D,Izadpanah K,Rolauffs B,Sudkamp NP,Schmal H

更新日期：2018-02-23 00:00:00

abstract：:Sharing the same precursor cell lineage located in the bone marrow, mesenchymal stroma/stem cells (MSCs), osteoblasts and adipocytes have a reciprocal relationship in differentiation and function. The nuclear transcription factor peroxisome-proliferator- activated receptor-gamma (PPAR-γ) has been found expressed in bo...

journal_title：Current stem cell research & therapy

authors： Zhuang H,Zhang X,Zhu C,Tang X,Yu F,Shang GW,Cai X

更新日期：2016-01-01 00:00:00

abstract：:Regenerative medicine (RM) is an interdisciplinary field that uses different approaches to accelerate the repair and regeneration or replace damaged or diseased human cells or tissues to achieve normal tissue function. These approaches include the stimulation of the body's own repair processes, transplantation of prog...

journal_title：Current stem cell research & therapy

authors： Asgharzad S,Alizadeh A,Arab S

更新日期：2021-01-12 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are ideal candidates for different cellular therapies due to their simple isolation, extensive expansion potential, and low immunogenicity. For various therapeutic approaches, such as bone and cartilage repair, MSCs are expected to replace the damaged tissues by direct differentiation. Ho...

journal_title：Current stem cell research & therapy

authors： Kuang W,Xu X,Lin J,Cao Y,Xu Y,Chen L,Jin L,Tan J

更新日期：2015-01-01 00:00:00