Prenatal Triptan Exposure and Internalising and Externalising Behaviour Problems in 3-Year-Old Children: Results from the Norwegian Mother and Child Cohort Study.

Abstract:

BACKGROUND:Triptans are commonly prescribed for migraine, a pain condition that is highly prevalent in women of childbearing age. No prior studies have investigated associations between exposure to triptans during fetal life and risk of externalising and internalising behaviours in children. METHODS:This study was set in the Norwegian Mother and Child Cohort study, a prospective birth cohort. A total of 41,173 live, singleton births without major malformations present at 36-month post-partum follow-up were included in this study; 396 used a triptan during pregnancy, 798 used a triptan prior to pregnancy only, 3291 reported migraine without triptan use, and 36,688 reported no history of migraine or triptan use. Marginal structural models were used to analyse the association between timing of triptan exposure and neurodevelopmental outcome. RESULTS:Children exposed to triptans during pregnancy had a 1.39-fold increased risk of externalising behaviours compared with those whose mothers used triptans prior to pregnancy only (95% CI 0.97, 1.97), a 1.36-fold increased risk compared with the unmedicated migraine group (95% CI 1.02, 1.81), and a 1.41-fold increased risk compared with the population comparison group (95% CI 1.08, 1.85). The greatest risk was associated with first trimester exposure (RR 1.77, 95% CI 0.98, 3.14). Risk differences were small, ranging from 3-6%. CONCLUSIONS:This study found an increased risk of clinically relevant externalising behaviours in children with prenatal exposure to triptans, and this risk was highest for first trimester exposure. Absolute risks were small, and the results may be due to confounding by underlying migraine severity.

authors

Wood ME,Lapane K,Frazier JA,Ystrom E,Mick EO,Nordeng H

doi

10.1111/ppe.12253

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

190-200

issue

2

eissn

0269-5022

issn

1365-3016

journal_volume

30

pub_type

杂志文章
  • The association of birth interval, maternal age and season of birth with the fertility of daughters: a retrospective cohort study based on family reconstitutions from nineteenth and early twentieth century Quebec.

    abstract::In a historical follow-up study, we evaluated the association of the fertility of daughters with five perinatal factors: short (< 15 months) or long (> or = 45 months) preceding birth interval, low (< or = 20 years) or advanced (> or = 40 years) maternal age and season of birth. We used data concerning 2062 women marr...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-3016.1999.00215.x

    authors: Smits L,Zielhuis G,Jongbloet P,Bouchard G

    更新日期:1999-10-01 00:00:00

  • Delivery method and self-reported postpartum general health status among primiparous women.

    abstract::Despite nearly four million deliveries in the United States each year, minimal information exists on unintended health consequences following childbirth, particularly in relation to delivery method. The purpose of this study was to assess the association between method of delivery and the general health status, sexual...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-3016.2001.00345.x

    authors: Lydon-Rochelle MT,Holt VL,Martin DP

    更新日期:2001-07-01 00:00:00

  • Umbilical Cord Serum 25-Hydroxyvitamin D Concentrations and Relation to Birthweight, Head Circumference and Infant Length at Age 14 Days.

    abstract:BACKGROUND:Insufficient supply of vitamin D during early development may negatively affect offspring growth. METHODS:We examined the association between umbilical cord (UC) serum 25-hydroxyvitamin D (25(OH)D) concentrations and infant size in a study of two Faroese birth cohorts of 1038 singleton infants. In the third...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ppe.12288

    authors: Dalgård C,Petersen MS,Steuerwald U,Weihe P,Grandjean P

    更新日期:2016-05-01 00:00:00

  • Validity of Self-Reported Pre-Pregnancy Weight and Body Mass Index Classification in an Integrated Health Care Delivery System.

    abstract:BACKGROUND:Self-reported weight prior to pregnancy is prone to error. We utilised a measured pre-conceptional weight from the electronic health record (EHR) to investigate error in recalled pre-pregnancy body mass index (BMI) category and compared how associations between pre-pregnancy BMI and pregnancy outcomes varied...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12286

    authors: Han E,Abrams B,Sridhar S,Xu F,Hedderson M

    更新日期:2016-07-01 00:00:00

  • Glutamine-enriched enteral nutrition in very low birthweight infants and allergic and infectious diseases at 6 years of age.

    abstract::In a previous randomised controlled trial, we found that glutamine-enriched enteral nutrition in 102 very low birthweight (VLBW) infants decreased both the incidence of serious infections in the neonatal period and the risk of atopic dermatitis during the first year of life. We hypothesised that glutamine-enriched ent...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2010.01173.x

    authors: van Zwol A,Moll HA,Fetter WP,van Elburg RM

    更新日期:2011-01-01 00:00:00

  • Epidemiology of neonatal group B streptococcal disease in The Netherlands 1997-98.

    abstract::Group B streptococcal (GBS) infection is still an important cause of morbidity and mortality in newborn infants. In The Netherlands, there are no published data on the incidence of neonatal GBS infection. We collected data of all infants with GBS disease during the first 3 months of life, as reported to the Dutch Paed...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-3016.2002.00437.x

    authors: Trijbels-Smeulders M,Gerards LJ,M PC,de Jong P,van Lingen RA,Adriaanse AH,de Jonge GA,Kollée LA

    更新日期:2002-10-01 00:00:00

  • A case-control study of infant, maternal and perinatal characteristics associated with deformational plagiocephaly.

    abstract::Deformational plagiocephaly, an abnormal asymmetric flattening of infants' heads, is diagnosed in approximately 10% of infants. The prevalence of plagiocephaly has increased dramatically since 1992 when it was first recommended that infants be placed to sleep in a non-prone position to reduce the risk of sudden infant...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2009.01038.x

    authors: McKinney CM,Cunningham ML,Holt VL,Leroux B,Starr JR

    更新日期:2009-07-01 00:00:00

  • Validity of birth certificate-derived maternal weight data.

    abstract:BACKGROUND:Studies using vital records-based maternal weight data have become more common, but the validity of these data is uncertain. METHODS:We evaluated the accuracy of prepregnancy body mass index (BMI) and gestational weight gain (GWG) reported on birth certificates using medical record data in 1204 births at a ...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12120

    authors: Bodnar LM,Abrams B,Bertolet M,Gernand AD,Parisi SM,Himes KP,Lash TL

    更新日期:2014-05-01 00:00:00

  • The analysis of recurrence risk as an epidemiological tool.

    abstract::Recurrence risk provides information on the heterogeneity of risk in the population, and thus is useful for aetiological studies. While recurrence risk is observable in many areas of epidemiology, it is particularly accessible in the study of perinatal events. High recurrence rates of pregnancy problems suggest geneti...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2007.00830.x

    authors: Wilcox AJ

    更新日期:2007-07-01 00:00:00

  • Risk factors for cryptorchidism: a nested case-control study.

    abstract::A nested case-control study of cryptorchidism (i.e. undescended testicles) was undertaken as part of a hospital-based cohort study of 6699 singleton male neonates in New York City. Since some of the cryptorchid infants experienced spontaneous descent of their testes, separate analysis was performed for this third grou...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.1996.tb00024.x

    authors: Berkowitz GS,Lapinski RH

    更新日期:1996-01-01 00:00:00

  • Exposure to tobacco smoke prenatally and during infancy and risk of hearing impairment among children in Japan: A retrospective cohort study.

    abstract:BACKGROUND:Previous studies of the association between tobacco smoke and hearing loss in children are limited, involve small samples and are cross-sectional. We investigated the association of maternal smoking during pregnancy and exposure to tobacco smoke at age 4 months with hearing impairment at age 3 years in child...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12477

    authors: Wilunda C,Yoshida S,Tanaka S,Kanazawa Y,Kimura T,Kawakami K

    更新日期:2018-09-01 00:00:00

  • Enrolment into Birth to Ten (BTT): population and sample characteristics.

    abstract::The population under study in the South African longitudinal study of urban children and their families, 'Birth to Ten' (BTT), comprised all births during a 7-week period from April to June 1990 in Soweto-Johannesburg. Specification of the population base for the cohort was hampered by a number of flaws in the notific...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.1995.tb00124.x

    authors: Richter LM,Yach D,Cameron N,Griesel RD,de Wet T

    更新日期:1995-01-01 00:00:00

  • Prenatal maternal stress and early caregiving experiences: implications for childhood asthma risk.

    abstract::There is still much debate as to the pathways through which some children develop asthma and others do not. One possible mechanism outlined here concerns the way in which stress may influence the neuroendocrine system and thence the immune system. Supporting evidence from animal experiments suggests that maternal pren...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2007.00879.x

    authors: Wright RJ

    更新日期:2007-11-01 00:00:00

  • Early pregnancy changes in bacterial vaginosis-associated bacteria and preterm delivery.

    abstract:BACKGROUND:We evaluated the importance of measuring early vaginal levels of eight bacterial vaginosis (BV)-associated bacteria, at two points in pregnancy, and the risk of spontaneous preterm delivery (SPTD) among pregnant women and the subgroup of pregnant women with a history of preterm delivery (PTD). METHODS:This ...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ppe.12106

    authors: Nelson DB,Hanlon A,Nachamkin I,Haggerty C,Mastrogiannis DS,Liu C,Fredricks DN

    更新日期:2014-03-01 00:00:00

  • A feeling of well-being accompanied by a period of prosperity and birthweight in Chile: a possible link?

    abstract::The aims of the study were to describe the trend in birthweight from 1985 to 2000 in Chile and ascertain the possible factors that may explain the changes in birthweight during the period. We used time series of birthweight and length at birth of all live births (n > 4,000,000). Multivariable regression analyses were ...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2005.00673.x

    authors: Amigo H,Vargas C,Rona RJ

    更新日期:2005-11-01 00:00:00

  • Early postnatal growth and neurodevelopment in children born moderately preterm or small for gestational age at term: A systematic review.

    abstract:BACKGROUND:Clinicians' interest in the long-term effects of early postnatal growth (EPG) is growing. There is compelling evidence linking rapid EPG with later cardiovascular risk, but its neurodevelopmental benefits still remain hypothetical in individuals born moderately preterm (MP) or small for gestational at term (...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章,评审

    doi:10.1111/ppe.12468

    authors: Taine M,Charles MA,Beltrand J,Rozé JC,Léger J,Botton J,Heude B

    更新日期:2018-05-01 00:00:00

  • Are selection criteria for healthy pregnancies responsible for the gap between fetal growth in the French national Elfe birth cohort and the Intergrowth-21st fetal growth standards?

    abstract:BACKGROUND:The Intergrowth-21st (IG) project proposed prescriptive fetal growth standards for global use based on ultrasound measurements from a multicounty study of low-risk pregnancies selected using strict criteria. We examined whether the IG standards are appropriate for fetal growth monitoring in France and whethe...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12526

    authors: Heude B,Le Guern M,Forhan A,Scherdel P,Kadawathagedara M,Dufourg MN,Bois C,Cheminat M,Goffinet F,Botton J,Charles MA,Zeitlin J

    更新日期:2019-01-01 00:00:00

  • Using cervical mucus and other easily observed biomarkers to identify ovulation in prospective pregnancy trials.

    abstract::To help fulfil the objectives of prospective studies of pregnancy and human development, such as the National Children's Study, there is a need to pinpoint ovulation and conception in a cohort of women. This paper discusses the suitability of using natural and easily observed markers of ovulation for detection of the ...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2006.00767.x

    authors: Zinaman MJ

    更新日期:2006-11-01 00:00:00

  • Down's syndrome: occurrence and outcome in the north of England, 1985-99.

    abstract::This study reports changes in the prevalence and outcome of Down's syndrome pregnancies within a 15-year period in a defined geographical population in the north of England. Cases of Down's syndrome in births and terminations of pregnancy occurring between 1985 and 1999, were identified from the Northern Congenital Ab...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-3016.2003.00463.x

    authors: Bell R,Rankin J,Donaldson LJ,Northern Congenital Abnormality Survey Steering Group.

    更新日期:2003-01-01 00:00:00

  • Recurrence of severe maternal morbidity: A population-based cohort analysis of California women.

    abstract:BACKGROUND:Severe maternal morbidity (SMM) has increased in the United States by 45% in the last decade. While the recurrence of several adverse pregnancy outcomes from one pregnancy to the next has been established, the recurrence risk of SMM is unknown. OBJECTIVE:To determine whether women who have SMM in a first pr...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12714

    authors: Bane S,Wall-Wieler E,Lyndon A,Carmichael SL

    更新日期:2020-11-06 00:00:00

  • Reports of birthweight by adolescents and their mothers: comparing accuracy and identifying correlates.

    abstract::Birthweight is associated with health outcomes throughout the lifespan. Official birthweight records are not always available, and researchers must rely on self-reports for birthweight information. This study evaluates the accuracy of adolescent self-reports of birthweight, using medical records as a standard, and com...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2006.00757.x

    authors: Lucia VC,Luo Z,Gardiner JC,Paneth N,Breslau N

    更新日期:2006-11-01 00:00:00

  • The exposome--exciting opportunities for discoveries in reproductive and perinatal epidemiology.

    abstract::Understanding the mechanisms that underlie successful human reproduction and development is an ambitious goal, given the many unique methodological challenges surrounding such study. These challenges are well understood by reproductive and perinatal epidemiologists and include its conditional nature, unobservable yet ...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12040

    authors: Buck Louis GM,Yeung E,Sundaram R,Laughon SK,Zhang C

    更新日期:2013-05-01 00:00:00

  • Changing risks of stillbirth and neonatal mortality associated with maternal age in Western Australia 1984-2003.

    abstract::There has been a trend over the past two decades in some Western countries for women to delay childbearing, a factor associated with an increased risk of perinatal mortality (stillbirth and neonatal death). While the rates of stillbirth and neonatal mortality have improved in some countries, it has not been establishe...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2007.00849.x

    authors: O'Leary CM,Bower C,Knuiman M,Stanley FJ

    更新日期:2007-11-01 00:00:00

  • Performance of a new pubertal self-assessment questionnaire: a preliminary study.

    abstract::We describe the performance of a new, self-assessment questionnaire that aims to measure pubertal status by using gender-specific line drawings of the Tanner puberty stages. The study was carried out on 103 children aged 12-16 years attending a paediatric endocrinology outpatient clinic and used physical examination b...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-3016.2001.00317.x

    authors: Taylor SJ,Whincup PH,Hindmarsh PC,Lampe F,Odoki K,Cook DG

    更新日期:2001-01-01 00:00:00

  • Prevalence of febrile seizures in Dutch schoolchildren.

    abstract::During a scheduled visit to the school physician, the number of children with a history of febrile seizures was determined in 3570 children attending primary schools in the suburban area of the city of Rotterdam. At the age of 6 years, 140 had experienced at least one febrile seizure (3.9%, 95% confidence interval 3.3...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.1991.tb00699.x

    authors: Offringa M,Hazebroek-Kampschreur AA,Derksen-Lubsen G

    更新日期:1991-04-01 00:00:00

  • Relationships between air pollution and preterm birth in California.

    abstract::Air pollution from vehicular emissions and other combustion sources is related to cardiovascular and respiratory outcomes. However, few studies have investigated the relationship between air pollution and preterm birth, a primary cause of infant mortality and morbidity. This analysis examined the effect of fine partic...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2006.00759.x

    authors: Huynh M,Woodruff TJ,Parker JD,Schoendorf KC

    更新日期:2006-11-01 00:00:00

  • Alteration in vaginal microflora, douching prior to pregnancy, and preterm birth.

    abstract::We aimed to determine the relationship of douching prior to pregnancy and bacterial vaginosis (BV) during pregnancy on preterm birth, addressing individual and joint effects. We used a prospective cohort study and assessed vaginal microflora using gram stains and Nugent's criteria. Douching behaviour was based on self...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/j.1365-3016.2008.00970.x

    authors: Thorp JM Jr,Dole N,Herring AH,McDonald TL,Eucker B,Savitz DA,Kaczor D

    更新日期:2008-11-01 00:00:00

  • Rationale and design of the PRegnancy and Infant DEvelopment (PRIDE) Study.

    abstract:BACKGROUND:To optimise the health of pregnant women and their children by evidence-based primary and secondary prevention, more scientific knowledge is needed. To overcome the methodological limitations of many studies on pregnancy and child health, which often use a retrospective design, we established the PRIDE (PReg...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12023

    authors: van Gelder MM,Bretveld RW,Roukema J,Steenhoek M,van Drongelen J,Spaanderman ME,van Rumpt D,Zielhuis GA,Verhaak CM,Roeleveld N

    更新日期:2013-01-01 00:00:00

  • Epidemiology and Outcomes of Congenital Diaphragmatic Hernia in Croatia: A Population-Based Study.

    abstract:BACKGROUND:Outcomes of neonates with congenital diaphragmatic hernia (CDH) are variable; reports are frequently limited to the experience of single tertiary care centres-a possible source of bias. Population-based studies decrease survivor bias and provide additional insight into this high-mortality condition. The obje...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章

    doi:10.1111/ppe.12289

    authors: Grizelj R,Bojanić K,Vuković J,Novak M,Rodin U,Ćorić T,Stanojević M,Schroeder DR,Weingarten TN,Sprung J,Croatian Diaphragmatic Hernia Study Group.

    更新日期:2016-07-01 00:00:00

  • Maternal nutrition and birth outcomes: effect of balanced protein-energy supplementation.

    abstract::The nutritional status of a woman before and during pregnancy is important for a healthy pregnancy outcome. Maternal malnutrition is a key contributor to poor fetal growth, low birthweight (LBW) and short- and long-term infant morbidity and mortality. This review summarised the evidence on association of maternal nutr...

    journal_title:Paediatric and perinatal epidemiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-3016.2012.01308.x

    authors: Imdad A,Bhutta ZA

    更新日期:2012-07-01 00:00:00