Atrioventricular septal defect: From embryonic development to long-term follow-up.

Abstract:

:Atrioventricular septal defect (AVSD) covers a spectrum of heart anomalies with a common atrioventricular connection and has an incidence of 4-5.3 per 10.000 live births. About half of the AVSDs occur in patient with Down syndrome. This review provides a bench to bedside overview of AVSD. Developmental aspects, nomenclature, anatomy, and classification of AVSD are discussed. Furthermore an overview of genetic and maternal risk factors for AVSD is provided, and available literature on (fetal) diagnosis, surgical techniques and follow-up is presented. Special attention is given to differences in developmental, anatomical and prognostic factors of AVSD between non-syndromic and Down syndrome patients.

journal_name

Int J Cardiol

authors

Calkoen EE,Hazekamp MG,Blom NA,Elders BB,Gittenberger-de Groot AC,Haak MC,Bartelings MM,Roest AA,Jongbloed MR

doi

10.1016/j.ijcard.2015.09.081

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

784-95

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(15)30523-4

journal_volume

202

pub_type

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