Abstract:
BACKGROUND:Higher systolic blood pressure (SBP) has been reported to be associated with a better prognosis in heart failure (HF) patients. This study aimed to investigate the prognostic impact of hypertension in patients hospitalized with systolic HF. METHODS:Pooled analysis of data from three Korean observational studies was performed. Patients ≥18 years hospitalized with systolic HF (ejection fraction ≤45%) (n=3538) were compared for the incidence of 1-year all-cause mortality according to the presence of preexisting hypertension and SBP quartiles on admission. RESULTS:Patients with hypertension (prevalence, 51.6%) presented more often with diabetes (43.9% vs. 23.0%, p<0.001) and chronic kidney disease (14.1% vs. 5.7%, p<0.001). During the 1-year follow-up, patients with hypertension showed similar cumulative incidences of all-cause mortality as those without hypertension (8.3% vs. 8.4%, p=0.900). Conversely, patients with higher SBP on admission had a lower incidence of all-cause death (quartile 4 vs. 1: 6.7% vs. 11.3%, p for trend=0.004). In the multivariate analysis, an increase in SBP of 10 mmHg was associated with an 8.5% risk reduction of all-cause death (hazard ratio: 0.915, 95% confidence interval: 0.853-0.981, p=0.013). CONCLUSIONS:Higher SBP on admission was independently associated with a lower risk of 1-year all-cause mortality in systolic HF.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Lee JH,Lee JW,Youn YJ,Ahn MS,Ahn SG,Kim JY,Lee SH,Yoon J,Oh J,Kang SM,Jeon ES,Choi DJ,Ryu KH,Yoo BSdoi
10.1016/j.jjcc.2015.08.005subject
Has Abstractpub_date
2016-05-01 00:00:00pages
418-23issue
5eissn
0914-5087issn
1876-4738pii
S0914-5087(15)00243-9journal_volume
67pub_type
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