Abstract:
BACKGROUND:Endoscopic gastric balloons have been used effectively as weight loss devices for decades, but the requirement for endoscopy and sedation poses several limitations. The goal of this pilot study was to evaluate the safety and performance of a prototype version of Elipse™, a procedureless gastric balloon. METHODS:Eight patients (mean BMI = 31.0 kg/m(2)) participated in this study. Each patient swallowed one Elipse™ balloon intended to remain in the stomach for 6 weeks, self-empty, and then pass. Each balloon was filled with 450 mL of filling fluid. Patients returned every 2 weeks for abdominal ultrasound. No specific diet or exercise plan was prescribed. RESULTS:All eight patients successfully swallowed the device. The most common adverse events were nausea and vomiting. There were no serious adverse events, and all balloons were excreted safely. Despite not being prescribed a diet or exercise plan, all eight patients lost weight. In 6/8 patients, the balloon remained full through 6 weeks, self-emptied, and passed. In one patient, the balloon appeared partially collapsed on ultrasound after 11 days and was endoscopically punctured. One asymptomatic patient elected to have the balloon endoscopically punctured after 19 days. Both balloons passed in the stool after 4 days. In both cases, endoscopic examination of the upper GI tract showed no abnormalities. CONCLUSIONS:This pilot study demonstrates the safety and performance of Elipse™, a procedureless gastric balloon for weight loss. Future studies will test a commercial design filled to 550 mL intended to last in the stomach for at least 12 weeks.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Machytka E,Chuttani R,Bojkova M,Kupka T,Buzga M,Stecco K,Levy S,Gaur Sdoi
10.1007/s11695-015-1783-7subject
Has Abstractpub_date
2016-03-01 00:00:00pages
512-6issue
3eissn
0960-8923issn
1708-0428pii
10.1007/s11695-015-1783-7journal_volume
26pub_type
杂志文章相关文献
OBESITY SURGERY文献大全abstract:BACKGROUND:Post intragastric balloon placement symptoms like nausea and vomiting have been the major cause of a high rate of early removal. Common therapy with ondansetron alone, or in combination, with prokinetic agents have been shown to have very little or no effect. Recently, an improved therapy based on aprepitant...
journal_title:Obesity surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s11695-019-03937-x
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:This study examines the effect of weight loss following laparoscopic Roux-en-Y gastric bypass (RYGBP) for morbid obesity on prescription drug costs in patients over the age of 54. METHODS:78 patients aged 55 to 75 who met the inclusion criteria were identified in a database of 1,060 morbidly obese patients ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892041975677
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:The effectiveness of gastric bypass for weight loss has been demonstrated. No study has documented the effect of this surgery on patient spouses' weight. Excess leftover food may be consumed by the spouses of gastric bypass patients, which may increase the total caloric intake compared to the preoperative in...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892053268426
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:The Roux-en-Y gastric bypass (RYGB) is one of the most commonly performed procedures for surgical weight loss. It has been shown that overweight may be associated with an increased risk of gastric cancer. However, the risk of remnant gastric cancer after RYGB has not been defined yet and the development of n...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1007/s11695-019-03892-7
更新日期:2019-08-01 00:00:00
abstract::We present a novel technique for the retrieval of intragastric balloons used in the treatment of patients with morbid obesity. Although specifically-designed instruments are available for this purpose, this simple technique makes use of instruments that are readily available in an endoscopy suite equipped for simple t...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892052993567
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The primary endpoint of this study was to assess the association of health-related quality of life (QoL) and the presence of psychopathology. The association of other patients' characteristics and of Cognitive Behavioral Assessment (CBA) scales with quality of life (QoL) was also evaluated. METHODS:100 cons...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892053268255
更新日期:2005-02-01 00:00:00
abstract:INTRODUCTION:Weight regain after laparoscopic Roux-en-Y gastric bypass (RYGB) occurs in up to 35% of patients. Revisional surgery may be applied. Conversion from RYGB to a long biliopancreatic limb (BPL) RYGB is a potential option for revisional surgery and short-term results are promising. METHODS:All patients who un...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-04348-8
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Leak following laparoscopic sleeve gastrectomy (LSG) is one of the most serious and devastating complications. Endoscopic stents can treat most early LSG leaks, but is not as effective for chronic LSG leaks/fistulae. The surgical options to treat a chronic leak/fistula after LSG are laparoscopic Roux en Y es...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-015-2018-7
更新日期:2016-03-01 00:00:00
abstract:INTRODUCTION:One-anastomosis-mini-gastric bypass (OAGB-MGB) is the second most popular gastric bypass procedure with remarkable weight loss results and comorbidity resolution rates. However, some concerns remain regarding its postoperative complications, including protein-calorie malnutrition (PCM). We hereby report ou...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-03741-7
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Laparoscopic sleeve gastrectomy (LSG) as a single-stage procedure has shown to be effective in achieving significant weight loss and resolving obesity-related co-morbidities. However, its nutrition consequences have not been extensively explored. This study aims to investigate weight loss and evolution of nu...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-016-2211-3
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:The staple line leakage is a dangerous complication of sleeve gastrectomy. Various strategies have been tried to reduce the leakage risk. The amniotic membrane (AmM) is the inner layer of the placental membranes and has anti-inflammatory, anti-fibrosis, and anti-scarring effects, and it also has lower immune...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-04027-8
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The purpose of the present study is to evaluate the impact of a health psychology-led bariatric rehabilitation service (BRS) on patient weight loss following bariatric surgery at 1 year. METHODS:A single-site open-randomised parallel group control trial based at St. Richard's Hospital in Chichester in the U...
journal_title:Obesity surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11695-014-1428-2
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Gastro-esophageal reflux disease (GERD) post-sleeve gastrectomy (SG) is a controversial issue and diagnostic dilemma. Strong heterogeneity exists in the assessment of reflux post-SG, and better diagnostic tools are needed to characterize symptomatic reflux. We aimed to determine the discriminant factors of s...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-05152-5
更新日期:2021-01-25 00:00:00
abstract::Limited information is available regarding reversal of gastric bypass. While reversal will lead to weight regain and return of comorbid conditions, procedure reversal is sometimes necessary due to complications. The decision to reverse versus revise is difficult; currently, there are no established guidelines. The obj...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-012-0715-z
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Laparoscopic adjustable gastric banding (LAGB) has gained widespread acceptance. However, the technique has problems intrinsic to the material wear and tear around the port and connecting tubing that can lead to failure. Port complications are considered to be minor; however, few studies have analyzed them, ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892053576604
更新日期:2005-03-01 00:00:00
abstract::Achalasia presenting in the context of morbid obesity is rare. The case is presented of a woman with achalasia and morbid obesity who was treated with simultaneous laparoscopic esophageal myotomy and gastric bypass. The sparse literature addressing these rare patients is reviewed and management considerations discusse...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9095-1
更新日期:2007-04-01 00:00:00
abstract::The remarkable control of diabetes by the gastric bypass remains to be explained. Although it may be totally due to the weight loss Induced by the operation, it is likely that the detour of the hormonally active foregut plays a role as well. This keynote address explores the pathophysiology of non-insulin-dependent di...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089292765559891
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:Bariatric surgery can improve glucose metabolism in obese patients with diabetes, but the factors that can predict diabetes remission are still under discussion. The present study aims to examine the impact of preoperative beta cell function on diabetes remission following surgery. MATERIALS AND METHODS:We ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-016-2300-3
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:The number of bariatric revisional cases has nearly doubled since 2011, and now comprises 13.6% of the total number of cases. The objective of this study is to evaluate the outcomes and safety of the two most common stapling revisional procedures, namely, sleeve and gastric bypass in comparison to primary ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3140-0
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:Growing evidence in the literature suggests that obesity is capable of altering reproductive hormone levels and male fertility. Effects on classic semen parameters and sperm DNA fragmentation (SDF), however, have not been properly established. Additionally, the impact of bariatric surgery (BS) on those paramete...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-04851-3
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Creating the proximal anastomosis in laparoscopic biliopancreatic diversion with duodenal switch (LBPD-DS) and Roux-en-Y gastric bypass (LRYGBP) is a critical step in ensuring the success of the procedures. The aim of this study was to assess the safety and efficiency of performing this anastomosis using a f...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089203321136656
更新日期:2003-02-01 00:00:00
abstract::Gastroesophageal reflux disease (GERD) and/or hiatus hernia (HH) are one of the most common disorders of the upper gastrointestinal tract. Despite the positive effect of sleeve gastrectomy (SG) regarding weight loss and improvement in obesity co-morbidities, there are concerns about the development of de novo gastroes...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1007/s11695-015-1906-1
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION:Female sexual dysfunction (FSD) among the obese women is often under diagnosed and ignored especially in Malaysia, a nation of conservative multiethnic society. There are only a few studies on FSD resolution post-bariatric surgery. The objective was to identify the rate and resolution or improvement of FSD...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-03722-w
更新日期:2019-05-01 00:00:00
abstract::We aimed to systematically review the literature comparing the safety of one-step versus two-step revisional bariatric surgery from laparoscopic adjustable gastric banding (LAGB) to Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG). There is debate on the safety of removing the gastric band and performing rev...
journal_title:Obesity surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11695-016-2082-7
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Massive weight loss following bariatric surgery frequently results in body contour deformities like ptotic and hypoplastic breasts, redundant abdominal tissue and loose skin especially in the medial thigh area. This redundant tissue can be used for breast augmentation in the case of hypertrophic ptotic breas...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089202320995655
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Altered cytokine secretion from dysfunctional adipose tissue or "adiposopathy" is implicated in obesity related inflammation and may mediate reduced cardiovascular disease (CVD) risk in response to weight loss after bariatric surgery. We hypothesized that bariatric surgery reduces CVD risk by favorably alter...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-011-0447-5
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:A technique for standard laparoscopic BPD was developed. METHODS:Standard laparoscopic BPD was performed in 26 morbidly obese patients with mean BMI 43. Details of the technique, using 6 trocars, and instrumentation are described. Intestinal limb lengths were measured fully stretched, and the gastric remnan...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1381/096089202762552692
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Gamma-glutamyltranspeptidase (GGT) levels are an independent risk marker for the development of type 2 diabetes (T2DM). We investigated the relationship between the newly identified serum GGT fractions and glucose metabolism in obese subjects before and after bariatric surgery. SUBJECTS/METHODS:T...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-017-3017-7
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The authors evaluated the impact of laparoscopic adjustable gastric banding (LAGB) on obesity-associated diseases in a series at 3 to 8 years postoperatively, namely diabetes, pulmonary disease, hypertension and knee joint pain. METHODS:145 morbidly obese patients underwent LAGB with mean age 38 years and p...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9118-y
更新日期:2007-05-01 00:00:00
abstract::Obesity and metabolic surgery (OMS) leads to several metabolic improvements, which often occur prior to substantial weight loss. Therefore, other factors in addition to weight loss contribute to the metabolic benefits. This literature review offers an overview of studies investigating bile acids (BAs) and their metabo...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1007/s11695-016-2272-3
更新日期:2016-10-01 00:00:00