Abstract:
BACKGROUND:Post intragastric balloon placement symptoms like nausea and vomiting have been the major cause of a high rate of early removal. Common therapy with ondansetron alone, or in combination, with prokinetic agents have been shown to have very little or no effect. Recently, an improved therapy based on aprepitant and ondansetron combination showed a significant improvement in symptoms management. Lack of aprepitant availability in several countries and patients difficulties to follow the right prescription convinced us to explore other pharmacological options. OBJECTIVE:Evaluate safety and efficacy of a netupitant and palonosetron-combined drug and to reduce and control post Elipse® placement symptoms METHODS: Between January and March 2018, 30 patients (9 male, 21 female), (mean weight 97.8 and mean BMI 34.7), underwent Elispe® placements, at 550 ml volume, in an outpatient fashion. All patients received a single pill 300 mg netupitant/0.5 mg palonosetron 6 h prior to placement. All patients received ondansetron 4 mg prescription to be taken as needed. A daily VAS score to report intensity of nausea, vomit, cramps, gastric pain, satiety for the first week post-placement was completed. RESULTS:4/30 (13%) reported vomiting on days 1, 2, and 3; 9/30 (30%) reported nausea higher than score 4 on days 1, 2, and 3; 8/30 (26.6%) reported gastric pain higher than score 4 on days 1, 2, and 3. CONCLUSION:In our experience, the use of a single-pill netupitant/palonosetron resulted to be very easy to administer and effective in reducing vomit, nausea, and gastric pain in 87%, 70%, and 73.4% patients respectively, ameliorating the post Elipse™ placements symptoms safely.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Ienca R,Giardiello C,Scozzarro A,di Cola RS,Di Lorenzo N,Juneja G,Lopez G,Badiuddin Fdoi
10.1007/s11695-019-03937-xsubject
Has Abstractpub_date
2019-09-01 00:00:00pages
2952-2956issue
9eissn
0960-8923issn
1708-0428pii
10.1007/s11695-019-03937-xjournal_volume
29pub_type
杂志文章,多中心研究相关文献
OBESITY SURGERY文献大全abstract:OBJECTIVE:The present study compared the therapeutic effects of great curvature plication with duodenal-jejunal bypass (GCP-DJB) and the commonly used sleeve gastrectomy (SG) in rats with type 2 diabetes mellitus (T2DM). METHODS:The rats were randomly divided into three groups: Control group (n = 6), SG group (n = 6),...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3459-6
更新日期:2018-12-01 00:00:00
abstract::The female population represents three-fourths of patients undergoing a bariatric procedure and could be scheduled for surgery in their postpartum period. We report a difficult case of a female patient who underwent a laparoscopic sleeve gastrectomy 6 weeks postpartum. The postpartum period is accompanied by pronounce...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-016-2154-8
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Upper gastrointestinal pathologies are common in bariatric patients. Preoperative esophagogastroduodenal endoscopy (EGD) should detect and treat pathologies that might alter the type of bariatric surgery. However, clinical consequences of these findings are often insignificant. The aim of this study was to a...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-017-2622-9
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Fatty acids (FAs) and adipokines such as adiponectin or interleukin-6 (IL-6) are known to modulate inflammation and the development of metabolic syndrome. Whether FA composition assessed in plasma triacylglycerols (TAGs), phospholipids (PLs) and non-esterified fatty acids (NEFAs) and adipose tissue (AT) PLs ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-012-0633-0
更新日期:2012-06-01 00:00:00
abstract::Complications of laparoscopic adjustable gastric banding occur in 10 - 20% of patients. However, hepatobiliary complications of this procedure are very rare. We report a unique case of gastric band misplacement around the hepato-duodenal ligament. The patient developed obstructive jaundice several months after the gas...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9029-y
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Gastro-esophageal reflux disease (GERD) post-sleeve gastrectomy (SG) is a controversial issue and diagnostic dilemma. Strong heterogeneity exists in the assessment of reflux post-SG, and better diagnostic tools are needed to characterize symptomatic reflux. We aimed to determine the discriminant factors of s...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-05152-5
更新日期:2021-01-25 00:00:00
abstract:BACKGROUND:The types of bariatric and the associated operations performed by academic and private surgeons were surveyed. METHODS:A survey containing 8 questions regarding type of practice, type of surgery, associated procedures during bariatric surgery, years in practice and bariatric training was e-mailed to all mem...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892042584058
更新日期:2004-11-01 00:00:00
abstract:INTRODUCTION:Surgical training today is all about minimally invasive surgery. With little or no experience and/or confidence in rapid, emergent conversion to an open procedure, how does the surgeon expeditiously do so? OBJECTIVES:The intent of this paper is to help those inexperienced in "open" techniques to quickly r...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-016-2095-2
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the incidence of intragastric migration of the Swedish adjustable gastric band (SAGB) and to evaluate the safety and effectiveness of gastroscopic band removal. METHODS:Between January 1996 and December 2001, 454 patients (381 women, 73 men) underwent a laparoscopic SAGB ...
journal_title:Obesity surgery
pub_type: 临床试验,杂志文章
doi:10.1381/096089202321088183
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Fibromyalgia is a chronic debilitating disorder affecting 3-5% of the US population. Treatment of this disorder is a challenge. The incidental finding of improvement of fibromyalgia following laparoscopic Roux-en-Y gastric bypass stimulated us to study this phenomenon. METHODS:A retrospective chart review o...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9505-z
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Our aim was to assess, in obese patients undergoing Roux-en Y gastric bypass surgery, the cumulative Helicobacter pylori (HP) eradication rates in two consecutive time spans (2006-2008 and 2009-2010). METHODS:The study adopted a 14-day clarithromycin-based triple therapy in first-line treatment as proposed ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-012-0747-4
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Long-term outcomes of gastric banding regarding depression and predictors of change in depression are still unclear. This prospective, controlled study investigated depression and self-acceptance in morbidly obese patients before and after gastric banding. METHODS:A total of 248 morbidly obese patients (mea...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9316-7
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Despite the established efficacy and safety of laparoscopic sleeve gastrectomy (LSG), controversy still exists on optimal operative technique, the resection distance from pylorus (DP) being among the most controversial issues. This study aimed to examine the effect of resection distance from pylorus on % exc...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-03923-3
更新日期:2019-09-01 00:00:00
abstract::Bariatric surgery is the most effective modality of achieving weight loss as well as the most effective treatment for type 2 diabetes mellitus (T2DM). Glucose-dependent insulinotropic polypeptide (GIP) is an incretin and is implicated in the pathogenesis of obesity and T2DM. Its role in weight loss and resolution of T...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1007/s11695-010-0305-x
更新日期:2011-02-01 00:00:00
abstract::Bariatric Surgery Centres of Excellence have been promoted by the International Federation for the Surgery of Obesity and Metabolic Disorders European Chapter to improve outcomes and security of patients. A retrospective analysis of our prospective database has been performed. Between May 2001 and September 2012, we o...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-013-0980-5
更新日期:2013-08-01 00:00:00
abstract::Two morbidly obese patients are presented. The first patient is a 38-year-old superobese female with BMI 56.2 in a wheelchair secondary to multiple sclerosis. The second patient is a 49-year-old female with BMI 47.7 confined to a wheelchair secondary to spinal cord transection due to a motor vehicle accident. Both pat...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9466-2
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Omental adipose tissue specimens of female rats that were fed a high fat (HF) diet were evaluated stereologically and histopathologically. To our knowledge, there is no stereological study on numerical density, nuclear height and volume of adipocytes in omental adipose tissue in the female rat fed a HF diet ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089206778869942
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Most bariatric treatments employ gastric volume reduction. However, there has been no appropriate tool that could assess the anatomical factors of the stomach, and few studies have investigated proper stomach measurement for bariatric treatment. Thus, this study aimed to objectively estimate the individual s...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-04189-5
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Bio-enteric intragastric balloon (BIB) insertion is gaining popularity for weight reduction in obese patients. We evaluated the efficacy, tolerability, and safety of BIB in the treatment of obesity. METHODS:A total of 173 Saudi obese patients [mean+/-SD age 34.5 +/- 11.6 years, 58 (33.5%) were men] who unde...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9654-0
更新日期:2010-09-01 00:00:00
abstract::Some sort of restriction of the pouch emptying is supported by many surgeons to allow a sustained weight loss through the use of a ring placed circumferentially around the gastric pouch. Most previous studies focused on the length of the ring, not the actual diameter of the gastric pouch outlet. This study aims to eva...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-010-0189-9
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:The authors evaluated the impact of laparoscopic adjustable gastric banding (LAGB) on obesity-associated diseases in a series at 3 to 8 years postoperatively, namely diabetes, pulmonary disease, hypertension and knee joint pain. METHODS:145 morbidly obese patients underwent LAGB with mean age 38 years and p...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9118-y
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Laparoscopic sleeve gastrectomy (LSG) as a single-stage procedure has shown to be effective in achieving significant weight loss and resolving obesity-related co-morbidities. However, its nutrition consequences have not been extensively explored. This study aims to investigate weight loss and evolution of nu...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-016-2211-3
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine whether the anatomicofunctional changes induced by vertical gastroplasty lead to pH alterations in the esophagus and body and antrum of the stomach. MATERIALS AND METHODS:23 non-smoking volunteers (3 men, 20 women) mean age 35.29 +/- SD 6.85 years, mean weight 163.17 +...
journal_title:Obesity surgery
pub_type: 临床试验,杂志文章
doi:10.1381/096089204322857690
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:There is a controversy about the best way to report results after bariatric surgery. Several indices have been proposed over the years such as percentage of total weight loss (%TWL), percentage of excess weight loss (%EWL), and percentage of excess body mass index loss (%EBMIL). More recently, it has been su...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-011-0480-4
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Traditionally, small intestinal bacterial overgrowth (SIBO) is diagnosed when there is an early peak in breath hydrogen or methane. Given unclear intestinal transit time in Roux-en-Y gastric bypass (RYGB) patients, it is unknown if the traditional approach at diagnosing SIBO is adequate in this patient popul...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3575-3
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Bariatric surgery is the only effective and long-lasting treatment of morbidly obese patients. However, the safety and efficacy of bariatric surgery in patients with hepatitis B viral (HBV) infection is not clear. The aim of the present study is to investigate whether HBV infection influences clinic features...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9346-1
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Sleeve gastrectomy (SG) is the most common bariatric procedure performed worldwide. However, without a standardised surgical technique, heterogeneous outcomes and complications such as gastro-oesophageal reflux disease (GERD) have been reported. The aim of this study was to identify reproducible anatomical c...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-05156-1
更新日期:2021-01-26 00:00:00
abstract:BACKGROUND:The effects of surgical weight loss (WL) on inflammatory biomarkers associated with sleep apnea remain unknown. We sought to determine if any biomarkers can predict amelioration of sleep apnea achieved by bariatric surgery. We hypothesized that surgical WL would substantially reduce severity of sleep apnea a...
journal_title:Obesity surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s11695-011-0359-4
更新日期:2011-09-01 00:00:00
abstract::African-Americans have been shown to have poorer weight loss outcomes after bariatric surgery, and many reasons for such outcomes have been postulated, including metabolic and genetic differences, socioeconomic factors, and differences in culture. African-Americans have also been noted to have differences from the maj...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-014-1213-2
更新日期:2014-08-01 00:00:00
abstract::BACKGROUND: Perhaps the most difficult problem in evaluating results of obesity surgery is the lack of standards for comparison, and the absence of consensus among professionals in definitions, classifications, and standard systems for reporting results, particularly in the analysis of successes and failures. METHODS:...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089296765556719
更新日期:1996-08-01 00:00:00