Impact of Phospholipid Transfer Protein in Lipid Metabolism and Cardiovascular Diseases.

Abstract:

:PLTP plays an important role in lipoprotein metabolism and cardiovascular disease development in humans; however, the mechanisms are still not completely understood. In mouse models, PLTP deficiency reduces cardiovascular disease, while its overexpression induces it. Therefore, we used mouse models to investigate the involved mechanisms. In this chapter, the recent main progresses in the field of PLTP research are summarized, and our focus is on the relationship between PLTP and lipoprotein metabolism, as well as PLTP and cardiovascular diseases.

journal_name

Adv Exp Med Biol

authors

Jiang XC

doi

10.1007/978-981-15-6082-8_1

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

1-13

eissn

0065-2598

issn

2214-8019

journal_volume

1276

pub_type

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