当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY期刊下所有文献 > Antibacterial effect of electrospun polycaprolactone/polyethylene oxide/vancomycin nanofiber mat for prevention of periprosthetic infection and biofilm formation.

Antibacterial effect of electrospun polycaprolactone/polyethylene oxide/vancomycin nanofiber mat for prevention of periprosthetic infection and biofilm formation.

Abstract：

OBJECTIVE:In this study, we developed a biocompatible and biodegradable vancomycin (VM)-eluting electrospun poly(ɛ-caprolactone) (PCL)/polyethylene oxide (PEO)/VM/PCL nanofiber mat. The purpose of this study was to evaluate the efficacy of this nanofiber mat for preventing methicillin-resistant Staphylococcus aureus (MRSA) biofilm on the ossicular prostheses and otitis media. MATERIALS AND METHODS:Fabrication of VM eluting nanofiber mat was carried out using PCL and PEO. The release of VM was assessed by spectrophotometry in vitro. The antibacterial effect was evaluated by inhibition zone test and biofilm formation test in vitro. And prevention of MRSA infection by guinea pig was assessed by otoendoscopy, temporal bone CT and histopathologic examination in vivo. RESULTS:VM released followed a triphasic pattern. VM eluting nanofiber mat prevented MRSA biofilm formation on the surface of ossicular prostheses regardless of materials in vitro, and MRSA otitis media in vivo. Otoendoscopy, temporal bone CT, and histopathologic findings revealed well ventilated middle ear. CONCLUSION:From these results, VM eluting nanofiber mat may be a promising method for prevention of MRSA periprosthetic infection and biofilm formation.

journal_name

Int J Pediatr Otorhinolaryngol

journal_title

International journal of pediatric otorhinolaryngology

authors

Jang CH,Cho YB,Jang YS,Kim MS,Kim GH

doi

10.1016/j.ijporl.2015.05.037

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

1299-305

issue

8

eissn

0165-5876

issn

1872-8464

pii

S0165-5876(15)00271-2

journal_volume

79

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY文献大全
  • Use of sound-elicited fetal heart rate accelerations to assess fetal hearing in the second and third trimester.

    abstract：OBJECTIVES:We previously reported that fetal heart rate (FHR) accelerations could be obtained after fetal sound stimulation. We examined FHR accelerations during 20-37 weeks gestational age (GA) in order to assess the optimal time for the test. METHODS:The fetus was stimulated from the maternal abdomen with pure tone ...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2020.110001

    authors： Hibiya-Motegi R,Nakayama M,Matsuoka R,Takeda J,Nojiri S,Itakura A,Koike T,Ikeda K

    更新日期：2020-06-01 00:00:00

  • Hamartoma of the middle ear: a case study.

    abstract：:Hamartomas and teratomas are rare tumors in children. Its location in head and neck is quite exceptional. An unusual case of hamartoma in the middle ear is reported in a 5-month-old child. The tumor was isolated without associated malformation. Definitive diagnosis was made after surgery and based on histological resu...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(02)00376-2

    authors： Baget S,François A,Andrieu-Guitrancourt J,Marie JP,Dehesdin D

    更新日期：2003-03-01 00:00:00

  • Audiovestibular sequelae of congenital cytomegalovirus infection in 3 children presumably representing 3 symptomatically different types of delayed endolymphatic hydrops.

    abstract：:Three cases of congenital cytomegalovirus (CMV) infection with long-term audiovestibular sequelae are presented. Case 1 had no hearing in one ear and severe progressive hearing loss in the other ear; he showed vestibular symptoms at the age of 4.5 years. Case 2 had severe but stationary hearing loss in one ear and sho...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/0165-5876(96)83899-7

    authors： Huygen PL,Admiraal RJ

    更新日期：1996-04-01 00:00:00

  • Childhood epiglottitis in recent years.

    abstract：:Fifty-five cases of acute epiglottitis were diagnosed and treated at the Children's Hospital of Philadelphia between 1985 and 1991. To evaluate the changing patterns of the disease over recent years, we compared the current results with those obtained from an earlier study reported at our institution in 1979. The over...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/0165-5876(93)90049-9

    authors： Kessler A,Wetmore RF,Marsh RR

    更新日期：1993-01-01 00:00:00

  • Effects of socioeconomic status on children with hearing loss.

    abstract：OBJECTIVE:Health care disparities are noted between different socioeconomic groups; it is crucial to recognize and correct disparities, if present, that extend to children with hearing loss. The objective of the study is to evaluate the effect of socioeconomic status (SES) on access to hearing rehabilitation and speech...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2018.10.032

    authors： Smith B,Zhang J,Pham GN,Pakanati K,Raol N,Ongkasuwan J,Anne S

    更新日期：2019-01-01 00:00:00

  • Otomicroscope in the emergency department management of pediatric ear foreign bodies.

    abstract：OBJECTIVE:To determine the effect of a dedicated otomicroscope in the emergency department (ED) management of complex ear foreign bodies (FB). METHODS:Prospective analysis of 85 patients with complex pediatric ear FB's. RESULTS:65 (76%) of 85 FB's were successfully removed in the ED. 54 (63%) had previous attempted r...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2008.12.010

    authors： Cederberg CA,Kerschner JE

    更新日期：2009-04-01 00:00:00

  • Can nasal endoscopy be used to predict residual symptoms after adenoidectomy for nasal obstruction?

    abstract：BACKGROUND:the efficacy of adenoidectomy in relieving nasal symptoms has been questioned. Although enlarged adenoids are often blamed for nasal obstruction, other causes can be missed if examination is not thorough. We suggest that endoscopy at the time of adenoidectomy may be useful to confirm large adenoids and exclu...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(01)00452-9

    authors： Kubba H,Bingham BJ

    更新日期：2001-05-11 00:00:00

  • Nasality evaluation of Turkish phonemes in vowel-consonant combinations.

    abstract：OBJECTIVES:The purpose of this study is to find average nasalance values of Turkish syllables with the nasometer. METHODS:This study is done at Hacettepe University Department of Otolaryngology Audiology and Speech Pathology Unit with 50 participating children. RESULTS:The normative nasalance values of Turkish phonem...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2011.03.031

    authors： Sarac ET,Kayikci ME,Ozkan S

    更新日期：2011-07-01 00:00:00

  • Comparison of three different surgical techniques for designing pharyngeal flaps according to findings of videonasopharyngoscopy and multiplanar videofluoroscopy.

    abstract：BACKGROUND:Velopharyngeal insufficiency (VPI) occurs when the velopharyngeal sphincter (VPS) is unable to completely seal anatomical closure between the nasal and oral cavities during speech. Palatal repair can restore VPS function but the prevalence of VPI after repair has been reported ranging from 20% to 40%. The co...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2019.02.022

    authors： Ysunza PA,Chaiyasate K,Rontal M,Shaheen K,Bartholomew B

    更新日期：2019-05-01 00:00:00

  • Role of tympanometric volume in paediatric tympanoplasty.

    abstract：OBJECTIVE:To determine the prognostic significance of "Tympaometric Volume" for paediatric tympanoplasty type I in a select age-group of 5-8 years. METHODS:A prospective study was conducted in 30 children with chronic suppurative otitis media-inactive mucosal disease of either sex. Pre-operative tympanometric volume w...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2015.08.027

    authors： Singh GB,Arora R,Garg S,Ranjan S,Kumar S

    更新日期：2015-11-01 00:00:00

  • Serum 25-hydroxyvitamin D3 levels in children with allergic or nonallergic rhinitis.

    abstract：OBJECTIVES:The relationship between vitamin D and allergic diseases such as asthma and atopic dermatitis is shown in several studies. But there is a lack of knowledge about vitamin D status in children with allergic rhinitis (AR). We aimed to investigate serum vitamin D levels of children with AR or nonallergic rhiniti...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2015.11.013

    authors： Dogru M,Suleyman A

    更新日期：2016-01-01 00:00:00

  • Single-stage tracheal resection for severe tracheal stenosis in older children.

    abstract：OBJECTIVE:While tracheal resection for management of tracheal stenosis is an effective technique that has been well described in adults, the results in children have been less encouraging, as children tolerate anastomotic tension less well than adults. We describe our current technique for the management of severe trac...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2003.08.054

    authors： Preciado D,Cotton RT,Rutter MJ

    更新日期：2004-01-01 00:00:00

  • Lipoid proteinosis of the larynx: a cause of voice change in the infant and young child.

    abstract：:Lipoid proteinosis is an autosomal recessive disorder that may display multiple systemic manifestations involving mucosal deposition of hyalin material. Skin and upper aerodigestive tract mucosal involvement predominate. In approximately two thirds of cases, voice change secondary to laryngeal involvement occurring at...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/0165-5876(88)90048-1

    authors： Savage MM,Crockett DM,McCabe BF

    更新日期：1988-02-01 00:00:00

  • Hemangioendothelioma of the temporal bone in a child.

    abstract：:Hemangioendothelioma is a vascular tumor of endothelial cell origin. It may involve bone or soft tissues and can behave like a benign or a malignant tumor. In the literature there are several case reports on the involvement of the head and neck region, but only three cases of temporal bone involvement, all of them in ...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(96)01480-2

    authors： Eliashar R,Saah D,Osin P,Sichel JY

    更新日期：1997-05-04 00:00:00

  • Ectopic thymus presenting as a subglottic mass: diagnostic and management dilemmas.

    abstract：:The commonest subglottic mass in infants is a congenital haemangioma, which is usually managed conservatively without a histological diagnosis. Ectopic cervical thymus is rare and usually presents as a cervical mass, with only one case of subglottic ectopic thymus reported to date. Due to its rarity, the diagnosis in ...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2004.11.022

    authors： Pai I,Hegde V,Wilson PO,Ancliff P,Ramsay AD,Daya H

    更新日期：2005-04-01 00:00:00

  • Pneumococcal polysaccharide capsular antigens in chronic secretory otitis media.

    abstract：:In a series of 163 ears with chronic, mucoid effusion, free or immune complex bound pneumococcal capsular polysaccharide antigens were demonstrated with Omniserum and counterimmunoelectrophoresis (CIEP) in 37 ears (23%). In crushed adenoid tissue this figure was 39% (42/107). Using type- or group-specific sera pneumoc...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(83)80115-3

    authors： Palva T,Lehtinen T,Virtanen H

    更新日期：1983-11-01 00:00:00

  • Normative data and construct validity of a cross-linguistic functional speech outcome, the Intelligibility in Context Scale: Italian (ICS-I).

    abstract：OBJECTIVES:The Intelligibility in Context Scale (ICS) is a parent-report scale, world-wide translated and widely validated, by which parents can rate their child's functional speech intelligibility according to seven different communicative partners. The study aimed to report and discuss the normative data of the Itali...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2020.109924

    authors： Piazzalunga S,Salerni N,Ambrogi F,Limarzi S,Visconti G,Schindler A

    更新日期：2020-05-01 00:00:00

  • Peripheral facial palsy after adenotonsillectomy in children.

    abstract：:Transient facial palsy is a rare complication after adenotonsillectomy. In this study, we report two cases who developed unilateral peripheral facial palsy immediately after adenotonsillectomy. The facial palsy in both cases completely recovered in 6 and 3h respectively without any treatment. We assumed the possible m...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2012.05.001

    authors： Lee KS,Lin KL,Chen YC

    更新日期：2012-09-01 00:00:00

  • Relationship between chronic nasal obstruction and craniofacial growth: an experimental model.

    abstract：:The aim of this paper was to verify if the growth of the nasomaxillary complex can be influenced by a purely functional alteration such as nasal obstruction, which was induced experimentally in a genetically controlled animal model. Sixty albino rats were employed. Twenty of them had the right nostril occluded by a sy...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(98)00049-4

    authors： Scarano E,Ottaviani F,Di Girolamo S,Galli A,Deli R,Paludetti G

    更新日期：1998-10-02 00:00:00

  • Prevalence of signs and symptoms of temporomandibular dysfunction in female adolescent athletes and non-athletes.

    abstract：OBJECTIVES:To compare the prevalence of signs and symptoms of temporomandibular dysfunction (TMD) in female adolescent athletes and non-athletes and to examine the association between signs and symptoms of TMD in female adolescents in different Tanner stages. METHODS:The subjects were 89 female basketball and handball...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2012.12.024

    authors： Weiler RM,Santos FM,Kulic MA,De Souza Lima MP,Pardini SR,Mori M,de Souza Vitalle MS

    更新日期：2013-04-01 00:00:00

  • Granulomatosis with polyangiitis presenting as facial nerve palsy in a teenager.

    abstract：:Granulomatosis with polyangiitis (GPA, previously known as Wegener's granulomatosis) is an autoimmune systemic small-vessel vasculitis, associated with the presence of anti-neurophil cytoplasmic antibodies with a cytoplasmic staining pattern (c-ANCA). It is characterized by necrotizing granulomas, usually affecting th...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2018.02.009

    authors： Wang JC,Leader BA,Crane RA,Koch BL,Smith MM,Ishman SL

    更新日期：2018-04-01 00:00:00

  • The auditory performance in children using cochlear implants: effects of mental function.

    abstract：OBJECTIVE:Mental function is considered to affect the post-operative outcomes of deaf children with cochlear implants. The purpose of this study is to evaluate the effect of mental function on the auditory performance in children with cochlear implants. METHODS:In a retrospective review of data, 26 pre-lingual deafene...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2004.04.011

    authors： Yang HM,Lin CY,Chen YJ,Wu JL

    更新日期：2004-09-01 00:00:00

  • To give or not to give antibiotics in non-severe acute otitis media? The American Academy of Pediatrics guidelines that do not guide.

    abstract：OBJECTIVE:To assess whether the recently published guidelines of the American Academy of Pediatrics (AAP) on acute otitis media (AOM) are in line with the requirements set by the GRADE system (grading of recommendations assessment, development, and evaluation system of rating quality of evidence and grading strength of...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 社论

    doi：10.1016/j.ijporl.2014.04.044

    authors： Nikolopoulos TP

    更新日期：2014-07-01 00:00:00

  • Using an expanded scalp flap without fascial flap harvest or skin grafting for total auricular reconstruction in hemifacial microsomia with low hairline.

    abstract：BACKGROUND:Total auricular reconstruction for hemifacial microsomia patients with extremely low hairline is a tough challenge in plastic surgery. In this work, a brand new technique using a singer expanded scalp flap without skin graft and combined with intense pulse light treatments (IPLT) for ear reconstruction is de...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2019.109726

    authors： Chen Q,Wang B,Wang Y,Hu J,Zhang Q

    更新日期：2020-01-01 00:00:00

  • Reversible sensorineural hearing loss.

    abstract：:We present an unusual case of temporary sensorineural hearing loss in a 6-year-old child due to carbon monoxide. This was shown on both the audiograms and confirmed with objective testing using otoacoustic emissions. Carbon monoxide poisoning is one of the few recognised causes of reversible sensorineural hearing loss...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(02)00202-1

    authors： Lee C,Robinson P,Chelladurai J

    更新日期：2002-12-02 00:00:00

  • Laryngeal diversion in the treatment of chronic aspiration in children.

    abstract：:Chronic aspiration in children can be life-threatening, especially in patients with underlying pulmonary disorders. Numerous surgical procedures have been described to treat chronic aspiration. In patients with severe chronic aspiration, laryngeal diversion is the most effective procedure for reducing soilage of the p...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/0165-5876(89)90066-9

    authors： De Vito MA,Wetmore RF,Pransky SM

    更新日期：1989-12-01 00:00:00

  • Bilateral tension pneumothorax during pediatric bronchoscopy (high-frequency jet injection ventilation).

    abstract：:Bilateral tension pneumothorax complicating high-frequency jet injection ventilation during rigid open bronchoscopy for foreign body removal in a 3-year-old child is reported. Subcutaneous emphysema, bradycardia and low voltage of the QRS complex were the presenting symptoms. Disparition of heart dullness by percussio...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(84)80012-9

    authors： Ostfeld E,Ovadia L

    更新日期：1984-07-01 00:00:00

  • The conceptions of hearing impairment, causes and its management: a train survey.

    abstract：OBJECTIVE:To identify the perception of the train passengers about the cause and the management of hearing loss. METHODOLOGY:A total of 115 passengers, 90 males and 25 females, in the age range of 13-80 years (mean: 39.19, standard deviation: 15.4) years. RESULTS:From the survey, it is found that most of the particip...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/j.ijporl.2012.04.014

    authors： Kumar S,Rout N,Kumari P,Dey B

    更新日期：2012-08-01 00:00:00

  • Intractable pulmonary aspiration in children: which operation?

    abstract：:Intractable aspiration is a life-threatening medical problem. There are many surgical procedures for the treatment of intractable aspiration. Our experience with three children was reported here. After failing initial conservative measures, the first two patients had supraglottic laryngeal closure performed through an...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijporl.2005.05.010

    authors： Hafidh MA,Young O,Russell JD

    更新日期：2006-01-01 00:00:00

  • Spontaneous resolution of recurrent tonsillitis in pediatric patients on the surgical waiting list.

    abstract：OBJECTIVE:To assess the impact of the waiting list on the spontaneous resolution of recurrent acute tonsillitis in children. METHODS:We have evaluated 623 cases placed on the waiting list for elective tonsillectomy (with or without adenoidectomy) between February 1994 and May 1999 at our institution. In each child, ag...

    journal_title：International journal of pediatric otorhinolaryngology

    pub_type： 杂志文章

    doi：10.1016/s0165-5876(02)00128-3

    authors： Prim MP,de Diego JI,Larrauri M,Diaz C,Sastre N,Gavilan J

    更新日期：2002-08-01 00:00:00