Abstract:
BACKGROUND:Inflammation plays an important role in the progression and prognosis of hepatocellular carcinoma (HCC). Our aim is to explore the prognostic value of preoperative and postoperative peripheral lymphocyte differences and to develop a dynamic prognosis nomogram in hepatitis B virus-related HCC patients. METHODS:Important indicators related to overall survival (OS) are screened out by Cox proportional hazard models. The receiver operating characteristic curves, decision curve analysis curves, net reclassification improvement, and integrated discrimination improvement were used to evaluate the performance of the model. RESULTS:Lymphocyte (L) difference was an independent risk factor. It was further verified that the performance of the nomogram was significantly improved after the L difference was incorporated into the nomogram. The nomogram generated had the area under curves of 0.779, 0.775, and 0.793 at 3, 5, and 7 years after surgery, respectively. Our nomogram models showed significantly better performance in predicting the HCC prognosis compared to other models. And online webserver and scoring system table was built based on the proposed nomogram for convenient clinical use. CONCLUSIONS:It is newly found that L difference is an effective predictor of OS, and the nomogram based on this indicator can accurately predict the prognosis of HCC patients.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Luo D,Li H,Yu H,Zhang M,Hu J,Jin C,Chua M,Han Bdoi
10.1002/jso.26195subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1553-1568issue
8eissn
0022-4790issn
1096-9098journal_volume
122pub_type
杂志文章abstract::As patients with ovarian cancer are living longer, surgeons will be faced with the management of metastatic lesions amenable to resection more frequently. We present two patients with ovarian cancer metastatic to the breast who underwent resection for their metastases, but their outcomes differed significantly. After ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24055
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The psychosocial impact of local-regional thyroid cancer recurrence is not known. The aim of this study was to explore thyroid cancer patients' experiences relating to diagnosis and treatment of local-regional disease recurrence. METHODS:We conducted 15 semi-structured interviews with survivor...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23345
更新日期:2013-07-01 00:00:00
abstract::The history of a patient presenting with metachronous bilateral breast cancer displaying histiocytoid features is reviewed. Although regional metastases were noted, this patient has not demonstrated an aggressive systemic disease pattern. In the past, histiocytoid breast cancer has been classified as either a lipid-ri...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930310410
更新日期:1986-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To assess the surgical and survival outcomes after secondary cytoreductive surgery (SCRS) in patients with platinum-sensitive recurrent epithelial ovarian cancer (EOC) and to identify patients who would most benefit from SCRS. METHODS:Inclusion criteria consisted of (1) recurrent EOC; (2) dis...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21470
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Despite advances in early detection of colon cancer, a minority of patients still require urgent surgery. Whether such urgent conditions result in poor outcome remains a topic of debate. METHODS:Using a prospectively maintained database, patients suffering exclusively from colon cancer and re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25469
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Patients chosen for liver resection of colorectal liver metastases are a select group with minimal disease, favorable tumor biology and earlier presentation when compared to unresectable patients. Despite intense preoperative assessments, operative detection of occult unresectable disease is inevitable for a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20341
更新日期:2005-10-01 00:00:00
abstract::Since February, 1977, 735 patients having a history of receiving radiation therapy for benign conditions of the head and neck areas during infancy and childhood were examined in a thyroid screening program, and 159 patients were found to have palpable thyroid nodules. These patients had thyroid function tests and indi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930140316
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Reports of clinicopathological features and prognosis in patients with mucinous gastric carcinoma (MGC) are conflicting. The aim was to describe the clinicopathological features and prognosis of patients with MGC in comparison with nonmucinous gastric carcinoma (NMGC). METHODS:We reviewed the...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21533
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Following curative intent surgery (CIS) for colorectal liver metastasis (CRLM), patterns of recurrence and subsequent survival outcomes are not widely reported. METHODS:An institutional database (January 2002-December 2012) was reviewed to evaluate patterns of recurrence following CIS for CRLM. RESULTS:163...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23756
更新日期:2014-12-01 00:00:00
abstract::The adrenal glands are complex structures from which a variety of benign and malignant tumors may arise and are a common site of metastatic disease. Several radiopharmaceuticals are used for imaging the adrenals, including I-123/I-131 metaiodobenzylguanidine (MIBG), norcholesterol derivatives, In-111 pentetreotide and...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23162
更新日期:2012-10-01 00:00:00
abstract::To gauge the impact of screening mammography and opinions regarding surgical procedures on the pattern of primary surgical care of breast cancer, tumor registry statistics from 1980-81 were compared to those from 1987 at a large community hospital. Over the course of six years, there was a significant increase in the ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930450104
更新日期:1990-09-01 00:00:00
abstract:INTRODUCTION:Many surgeons use the "10% rule" to define whether a lymph node is a sentinel node (SLN) when staging malignant melanoma. However, this increases the number of SLN removed and the time and cost of the procedure. We examined the impact of raising this threshold on the accuracy of the procedure. METHODS:We ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20729
更新日期:2007-06-15 00:00:00
abstract::The use of preoperative imaging has become routine for many reconstructive microsurgeons to help localize perforators for planning of microvascular free flaps. However, with advancements in imaging technology, perforator mapping represents only one potential benefit as virtual planning and medical modeling, and flap t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25194
更新日期:2018-10-01 00:00:00
abstract::Lymph node involvement in colorectal cancer, one of the most important prognostic factors, can be sometimes underestimated. In this study the authors report the results of two different techniques of specimen preparation and examination. In 240 patients (Group I), histologic examination was performed using a conventio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930510305
更新日期:1992-11-01 00:00:00
abstract::A study was conducted to assess the suppression of segmental pancreatic allograft rejection by cyclosporine (CSA) alone in baboons and dogs, and subtotal marrow irradiation (TL1) alone and TL 1 in combination with CSA in baboons. Total pancreatectomy in the dog and primate provided a reliable diabetic model, induced a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930380217
更新日期:1988-06-01 00:00:00
abstract:BACKGROUND:Few studies have focused on distribution of lymph node metastasis. The aim of this study is to evaluate the prognostic significance of the location of involved lymph nodes in patients with advanced mid or low rectal cancer. METHODS:We defined proximal lymph node involvement (PLNp) as superior rectal and inf...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21966
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Immediate breast reconstruction has many advantages but is associated with higher complication rates than delayed reconstruction. Complications can delay the delivery of adjuvant cancer treatments. This study aimed to develop and validate a risk stratification model for the prediction of perioperative compli...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25714
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:B7-H4 is a novel molecular B7 ligand that plays an important role as a negative regulator of the T cell-mediated immune response. However, the clinical significance of B7-H4 expression in gastric cancer remains uncertain. Here, we assessed B7-H4 expression in blood of patients with gastric can...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21722
更新日期:2010-12-01 00:00:00
abstract::The result of percutaneous superfine-needle aspiration biopsy in 100 patients with intrathoracic lesions guided by simulator is reported. The success rate of aspiration biopsy was 94%, and no major complication was observed. The method of localization by simulator had advantages such as accuracy in localization, no li...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930400215
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To compare uterine leiomyosarcomas (LMS) and leiomyomas (LM) with normal myometrium in terms of microvessel density (MVD), and to correlate this parameter with vascular endothelial growth factor (VEGF) expression and clinical/pathological parameters. METHODS:An immunohistochemical technique, ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20055
更新日期:2004-05-01 00:00:00
abstract::Diffuse large cell lymphoma is frequently localized at the time of presentation, but the aggressive natural history of the disease in most patients has suggested that extensive and intensive radiation and/or chemotherapy is necessary to control this disease. We describe a patient who has remained free of disease for 2...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210116
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND:Scoring systems were developed to stratify patients with colorectal liver metastases considered for liver resection into different risk groups. Such scores have never been evaluated in recurrent liver metastases. The aim of this study was to evaluate whether these scores are applicable to patients with recur...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24959
更新日期:2018-05-01 00:00:00
abstract::This study details the case reports of two children who developed slipped capital femoral epiphyses (SCFE) after receiving external irradiation. The clinical and diagnostic features of postradiation SCFE are reviewed and discussed. Guidelines for the management of children who receive pelvic irradiation are presented....
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930360110
更新日期:1987-09-01 00:00:00
abstract::Precision medicine involves understanding the molecular drivers unique to an individual patient's cancer so that specific factors may be targeted with the goal of improved patient outcomes. The purpose of this article is to review standard of care and research grade (non-standard of care) biomarkers in breast cancer t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23732
更新日期:2015-01-01 00:00:00
abstract::Laparoscopic resection of colon cancer became mired in controversy when it appeared that the technique might be associated with an increased risk of tumor recurrence within the surgical incisions. This was not a uniform finding among all surgeons, however, and other evidence suggested that this did not occur in experi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20921
更新日期:2007-12-15 00:00:00
abstract::We have operated upon six patients with cervical esophageal carcinoma and reconstructed these with free jejunal graft. The pathology of all six patients was squamous cell carcinoma, and no patient had apparent distant metastasis. The procedure was a two team approach. While the surgical oncology team resected the esop...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930420307
更新日期:1989-11-01 00:00:00
abstract::The relationship between prior cholecystectomy and right-sided colon cancer was evaluated in a case-control study. The study population comprised 267 women with right-sided colon cancer (cases) and 268 women with left-sided colon cancer (controls). All patients were white females, aged between 40 and 69 years, and reg...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930300103
更新日期:1985-09-01 00:00:00
abstract::Robotic-assisted laparoscopy is now the most common surgical method for treatment of early-stage endometrial, cervical, and a growing number of ovarian cancers in the U.S. Para-aortic and pelvic lymphadenectomy is integral to surgical staging and subsequent treatment planning. This article reviews current staging outc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24005
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION:Irreversible electroporation (IRE) has shown promise for ablation of lesions in proximity to vital structures in the preclinical setting. This study aims to evaluate the safety and efficacy of IRE for hepatic tumors in the clinical setting. METHODS:An IRB approved prospective registry of patients undergoi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23280
更新日期:2013-04-01 00:00:00
abstract::A unique association between meningioma and breast cancer has recently been observed. A review of the literature reveals 33 such cases. Certain similarities exist between these two tumors. They each occur more frequently in women in the fifth and sixth decade, and pregnancy accelerates the symptoms of both entities. F...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930310309
更新日期:1986-03-01 00:00:00