Abstract:
UNLABELLED:This longitudinal study of glucose tolerance in the residents of a Jewish home for the aged (JHA) is now in its 25th year. Of 1,177 supposedly nondiabetic persons screened on admission from 1965 to 1986, 22.5% had impaired glucose tolerance (IGT), reflecting its undiagnosed prevalence among the Jewish elderly in the community. The incidence of IGT was lower in 1969-1973, when the average age on admission was 77 years, than in 1982-1986, when the average age was 83.5 years. However, aging was not the only factor affecting glucose tolerance (GT). The rise in the residents' age in the last 10 years was not accompanied by an increased rate of deterioration of GT in the annual screenings of 1970-1984, suggesting that there was a delay in the effect of age on IGT and diabetes mellitus (DM). This was attributed mainly to the multimodal antidiabetic regimen (ADR) prevailing in the JHA in those years. Relaxation of this regimen was associated with a marked increase in the incidence of IGT and DM in the screenings of 1985-1987. When 25 newly diagnosed diabetics were put on a diabetic diet, 60% had normal or improved glucose tolerance tests (GTT) one to five years later. By contrast, in over half of the 80 residents whose first GTT did not indicate diabetes and whose diet was not as strictly controlled, the repeat GTT showed deterioration and was diabetic in 31%. CONCLUSIONS:Screening led to early diagnosis and institution of antidiabetic measures, probably avoiding or postponing the need for antidiabetic medication with its risk of iatrogenic hypoglycemia.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Grobin Wdoi
10.1111/j.1532-5415.1989.tb06676.xsubject
Has Abstractpub_date
1989-12-01 00:00:00pages
1127-34issue
12eissn
0002-8614issn
1532-5415journal_volume
37pub_type
杂志文章abstract::The necessity and safety of an oral calcium (Ca) and vitamin D regimen was evaluated in a population of 66 independently living and 73 institutionalized elderly women over an 11-week winter period. The members of both groups were randomly assigned into trial and control groups. Serum Ca, creatinine, and calcidiol leve...
journal_title:Journal of the American Geriatrics Society
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journal_title:Journal of the American Geriatrics Society
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更新日期:1978-05-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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journal_title:Journal of the American Geriatrics Society
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journal_title:Journal of the American Geriatrics Society
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更新日期:2011-07-01 00:00:00
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更新日期:2001-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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doi:10.1111/j.1532-5415.1994.tb06551.x
更新日期:1994-08-01 00:00:00
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doi:10.1111/j.1532-5415.1997.tb03092.x
更新日期:1997-05-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1532-5415.2001.49037.x
更新日期:2001-02-01 00:00:00
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doi:10.1111/jgs.15371
更新日期:2018-07-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/jgs.12739
更新日期:2014-04-01 00:00:00
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doi:10.1111/j.1532-5415.1984.tb02009.x
更新日期:1984-03-01 00:00:00
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doi:10.1111/j.1532-5415.1993.tb01893.x
更新日期:1993-05-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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pub_type: 杂志文章
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更新日期:1982-01-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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更新日期:2004-09-01 00:00:00
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更新日期:1996-06-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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更新日期:2011-05-01 00:00:00
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更新日期:2000-02-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2008-10-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1986.tb04318.x
更新日期:1986-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1532-5415.1995.tb05814.x
更新日期:1995-04-01 00:00:00