Abstract:
:Helicobacter pylori and hepatitis A virus (HAV) are thought to have similar routes of transmission and epidemiology. This study investigated the seroprevalence of these 2 pathogens among children in rural, central Taiwan. Serum samples were collected from 856 children between 2010 and 2012 and levels of anti-HAV and anti-H. pylori antibodies were measured by ELISA. Questionnaires were used to investigate possible risk factors. The overall H. pylori and HAV infection rates were 6% and 0.8%, respectively. There was a significant difference in H. pylori infection rates (P value=0.008), but not HAV infection rates, between different age groups. H. pylori infection rates were significantly higher in children whose mothers had lower education levels. In contrast, HAV infection rates were significantly higher in children whose fathers had lower education levels. The risk of HAV infection was also 14.20-fold higher in children whose family members had traveled to China or Southeast Asia. No significant correlation was found between H. pylori and HAV seropositivity. The seroprevalences of H. pylori and HAV were low in rural central Taiwan. Universal HAV vaccination is highly recommended to prevent outbreak due to low seroprevalence.
journal_name
Jpn J Infect Disjournal_title
Japanese journal of infectious diseasesauthors
Wu MC,Sung CH,Chang YC,Ho CL,Wu CC,Wu KH,Lee CY,Yang KDdoi
10.7883/yoken.JJID.2014.321subject
Has Abstractpub_date
2015-01-01 00:00:00pages
494-503issue
6eissn
1344-6304issn
1884-2836journal_volume
68pub_type
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