Sister chromatid exchange in painters recently exposed to solvents.

Abstract:

:Epidemiologic studies have suggested that exposure to solvent-based materials in the painting trades is associated with an increased cancer risk. In order to determine if the solvent exposures of current union members of the International Brotherhood of Painters and Allied Tradesman (IBPAT) are associated with a genotoxic risk, we have measured the sister chromatid exchange (SCE) frequency in their peripheral blood lymphocytes. Previous reports have shown that chronic solvent exposure of these workers does not elevate SCE frequencies. We now report that acute exposure, estimated by the number of days worked over the month prior to venipuncture, is associated with elevated SCE levels in currently smoking workers. No elevation in SCE was associated with similar recent exposure in nonsmoking, solvent-exposed painters.

journal_name

Environ Res

journal_title

Environmental research

authors

Kelsey KT,Wiencke JK,Little FF,Baker EL Jr,Little JB

doi

10.1016/s0013-9351(89)80005-2

subject

Has Abstract

pub_date

1989-12-01 00:00:00

pages

248-55

issue

2

eissn

0013-9351

issn

1096-0953

pii

S0013-9351(89)80005-2

journal_volume

50

pub_type

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