Neutrophil-to-Albumin Ratio as a Biomarker of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.


OBJECTIVE:This study set out to investigate the relationships between the neutrophil-to-albumin ratio (NAR) in the early stages of aneurysmal subarachnoid hemorrhage (aSAH) and the occurrence of delayed cerebral ischemia (DCI). METHODS:A total of 439 patients with aSAH were included in this retrospective study. NAR assessment was conducted on admission. The relationship between NAR and DCI was analyzed. RESULTS:Eighty-four patients (23.7%) experienced DCI. NAR levels were significantly higher in patients with DCI after aSAH than without DCI (median [interquartile range] 0.350 [0.274-0.406] vs. 0.240 [0.186-0.300]; P < 0.001). NAR levels were correlated with World Federation of Neurological Surgeons (WFNS) grade and modified Fisher (mFisher) grade (r = 0.505 and 0.394, respectively). NAR and mFisher grade were the independent predictors of DCI. Under receiver operating characteristic curve, NAR levels exhibited a significant discriminatory capability (area under the curve [95% confidence interval] 0.812 [0.740-0.823]; P < 0.001). The predictive power of NAR levels was similar to mFisher grade (P > 0.05). CONCLUSIONS:NAR, in positive correlation with the severity of hemorrhage, appears to be a novel predictive biomarker of DCI after aSAH.


World Neurosurg


World neurosurgery


Zhang X,Liu Y,Zhang S,Wang C,Zou C,Li A




Has Abstract


2020-12-26 00:00:00








  • Is Extended Lesionectomy Needed for Patients with Cerebral Cavernous Malformations Presenting with Epilepsy? A Meta-Analysis.

    abstract:OBJECTIVE:To determine whether extended lesionectomy is needed for patients with cerebral cavernous malformations presenting with epilepsy as compared with lesionectomy. METHODS:A literature search of PubMed, Embase, Web of Science, Clinical Trials and Cochrane Central Register of Controlled Trials was performed for p...

    journal_title:World neurosurgery

    pub_type: 杂志文章,meta分析


    authors: Shang-Guan HC,Wu ZY,Yao PS,Chen GR,Zheng SF,Kang DZ

    更新日期:2018-12-01 00:00:00

  • Spinal Intradural Escherichia coli Abscess Masquerading as a Neoplasm in a Pediatric Patient with History of Neonatal E. coli Meningitis: A Case Report and Literature Review.

    abstract:BACKGROUND:Central nervous system abscesses frequently can be seen in the immunocompromised population and most commonly consist of intracranial collections in the adult patient. Spinal intradural abscesses are less commonly encountered, and there are even fewer numbers in the pediatric population with a concordant abs...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Kim M,Simon J,Mirza K,Swong K,Johans S,Riedy L,Anderson D

    更新日期:2019-06-01 00:00:00

  • Surgical treatments of myelopathy caused by cervical ligamentum flavum ossification.

    abstract:OBJECTIVE:To present a small case series reporting the outcomes of surgical treatment for myelopathy caused by cervical ossification of the ligamentum flavum (OLF). METHODS:The authors assessed 15 cases of myelopathy caused by cervical OLF. Patients were eight women and seven men 37-75 years old (mean age 59.7 years)....

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Yang J,Ni B,Xie N,Guo Q,Wang L

    更新日期:2011-03-01 00:00:00

  • Virtual Cerebral Aneurysm Clipping with Real-Time Haptic Force Feedback in Neurosurgical Education.

    abstract:OBJECTIVE:Realistic, safe, and efficient modalities for simulation-based training are highly warranted to enhance the quality of surgical education, and they should be incorporated in resident training. The aim of this study was to develop a patient-specific virtual cerebral aneurysm-clipping simulator with haptic forc...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Gmeiner M,Dirnberger J,Fenz W,Gollwitzer M,Wurm G,Trenkler J,Gruber A

    更新日期:2018-04-01 00:00:00

  • Prevalence and Incidence of Drug-Resistant Mesial Temporal Lobe Epilepsy in the United States.

    abstract:OBJECTIVE:We reviewed data on the epidemiology of epilepsy in the United States and estimated the prevalence and incidence of drug-resistant temporal lobe epilepsy (TLE) due to hippocampal sclerosis (HS) based on extrapolation from the available data drawn from the literature. METHODS:We searched the electronic databa...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Asadi-Pooya AA,Stewart GR,Abrams DJ,Sharan A

    更新日期:2017-03-01 00:00:00

  • Affinity of Mucormycosis for Basal Ganglia in Intravenous Drug Users: Case Illustration and Review of Literature.

    abstract::Central nervous system mucormycosis is an aggressive fungal infection often ending in fatality. The usual circumstance is an immunocompromised individual presenting with rapidly progressive rhinocerebral involvement. An extremely rare variant of central nervous system mucormycosis isolated to the basal ganglia in an i...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Hazama A,Galgano M,Fullmer J,Hall W,Chin L

    更新日期:2017-02-01 00:00:00

  • PulseRider for Treatment of Wide-Neck Bifurcation Intracranial Aneurysms: 6-Month Results.

    abstract:BACKGROUND/OBJECTIVE:PulseRider is a new endovascular stent dedicated to treat bifurcation intracranial aneurysms with a wide neck. Our purpose was to evaluate 6-month clinical and anatomic results of the device when used to facilitate endovascular coiling of wide-neck bifurcation aneurysms. METHODS:Unruptured intracr...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Gory B,Spiotta AM,Di Paola F,Mangiafico S,Renieri L,Consoli A,Biondi A,Riva R,Labeyrie PE,Turjman F

    更新日期:2017-03-01 00:00:00

  • Surgical Management of Lumbosacral Giant Invasive Spinal Schwannoma: A Case Report and Literature Review.

    abstract:BACKGROUND:Giant invasive spinal schwannomas (GISSs) comprise a rare, specific subtype of schwannomas that extend >2 spinal levels, erode vertebral bodies, and invade extraspinal tissues. Optimal surgical management of resulting spinal instability has yet to be determined, and overall there is limited published literat...

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    pub_type: 杂志文章,评审


    authors: Paulo D,Semonche A,Tyagi R

    更新日期:2018-06-01 00:00:00

  • Gadolinium-Based Contrast Agent Extravasation Mimicking Subarachnoid Hemorrhage After Electroconvulsive Therapy.

    abstract:BACKGROUND:Electroconvulsive therapy (ECT) is a safe method that has been applied for many years in medical treatment-resistant depression treatment. In this case report, contrast extravasation due to deterioration of the blood-brain barrier after ECT mimicking subarachnoid hemorrhage (SAH) on magnetic resonance imagin...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Taydas O,Ogul H,Ozcan H,Kantarci M

    更新日期:2018-06-01 00:00:00

  • Comparison of Embolic Protection with Proximal and Distal Protection Devices: Periprocedural Complications, Clinical Outcomes, and Cerebral Embolic Lesions on Diffusion-Weighted Magnetic Resonance Imaging.

    abstract:OBJECTIVE:Two main types of embolic protection devices have been used during carotid artery stenting (CAS): distal protection devices (DPDs) and proximal protection devices (PPDs). We compared the complications, clinical outcomes, and new ischemic lesions on diffusion-weighted magnetic resonance imaging (DWI) studies b...

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    pub_type: 杂志文章


    authors: Kim MS,Rho MH,Hong HP,Park HJ,Chung PW,Won YS

    更新日期:2020-03-01 00:00:00

  • Primary High-Grade Osteosarcoma of the Clivus: A Case Report and Literature Review.

    abstract:BACKGROUND:Osteosarcoma is the second most common primary tumor of the skeletal system and the most common primary bone tumor. Usually occurring at the metaphysis of long bones, osteosarcomas are highly aggressive lesions that comprise osteoid-producing spindle cells. Craniofacial osteosarcomas comprise <8% and are bel...

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    pub_type: 杂志文章,评审


    authors: Mathkour M,Garces J,Beard B,Bartholomew A,Sulaiman OA,Ware ML

    更新日期:2016-05-01 00:00:00

  • Implementation of Intraoperative Computed Tomography for Deep Brain Stimulation: Pitfalls and Optimization of Workflow, Accuracy, and Radiation Exposure.

    abstract:OBJECTIVE:Deep brain stimulation (DBS) is an effective treatment for movement disorders. Stereotactic electrode placement can be guided by intraoperative imaging, which also allows for immediate intraoperative quality control. This article is about implementation and refining a workflow applying intraoperative computed...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Carl B,Bopp M,Gjorgjevski M,Oehrn C,Timmermann L,Nimsky C

    更新日期:2018-12-27 00:00:00

  • Intracranial Hypotension Following Traumatic Brain Injury: A Diagnostic and Therapeutic Challenge.

    abstract:BACKGROUND:Intracranial hypotension (IH) is a recognized cause of coma; however, the diagnosis is often challenging, especially in patients with superimposed traumatic brain injury. CASE DESCRIPTION:A 67-year-old woman became comatose following evacuation of bilateral acute subdural hematomas with concurrent respirato...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Low JCM,Shtaya A,Hettige S

    更新日期:2017-09-01 00:00:00

  • First Depiction of Flow Voids to Differentiate Pituicytomas from Giant Adenomas.

    abstract::Pituicytomas are rare low-grade glial lesions of neurohypophysis or adenohypophysis. They are often misdiagnosed as adenomas due to their similar morphology. Previous reports have underlined their nonspecific aspect. In our experience, presence of flow voids on magnetic resonance, which usually indicate hypervasculari...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Law-Ye B,Cholet C,Leclercq D

    更新日期:2018-01-01 00:00:00

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    abstract:BACKGROUND:Hydrogen peroxide (H2O2) solution is commonly used to irrigate wounds because of its hemostatic and antiseptic properties. Previous studies suggest that H2O2 can result in toxicity to keratinocytes and fibroblasts, but complications after H2O2 application, including oxygen embolism, which is one of the most ...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


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    更新日期:2020-06-01 00:00:00

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    abstract:BACKGROUND:During the past few years, the field of endovascular surgical neuroradiology has been expanding. Neurosurgeons, radiologists, and neurologists are currently being trained. We analyzed data from a national survey of endovascular training programs to assess the current training status and future projections. ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Strozyk D,Hanft SJ,Kellner CP,Meyers PM,Lavine SD

    更新日期:2010-07-01 00:00:00

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    abstract:OBJECTIVE:Rathke's cleft cysts (RCCs) may have various anatomic, clinical, and radiologic characteristics, which may be related to their differences in texture or consistency. The purpose of the study was to investigate RCCs based on consistency. METHODS:We retrospectively reviewed 25 cases of patients with RCCs who u...

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    pub_type: 杂志文章


    authors: Ozoner B,Aydin S,Akgun MY,Durmaz ES,Sahin S,Gazioglu N,Kizilkilic O,Kadioglu P,Tanriover N

    更新日期:2019-08-01 00:00:00

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    abstract:BACKGROUND:Previous studies compared outcomes of intracranial meningioma surgery in octogenarians with outcomes in younger patients without accounting for different tumor locations and sizes. The aim of the current study was to evaluate outcomes of intracranial meningioma surgery in octogenarians taking into account pa...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Hadanny A,Tzubery S,Hadelsberg U,Gonen L,Margalit N

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    abstract:BACKGROUND:Imaging of the craniocervical junction (CCJ) after trauma is crucial for injury detection and description. Of all the anatomic measurements of the CCJ, the normal value of atlanto-occipital interval (AOI) is not yet well established in adults. The aim of our study is to determine the normal values of the AOI...

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    pub_type: 杂志文章


    authors: Ekuma EM,Ndubuisi CA,Mezue W,Ohaegbulam S

    更新日期:2019-06-01 00:00:00

  • A Descriptive Analysis of Spinal Cord Arteriovenous Malformations: Clinical Features, Outcomes, and Trends in Management.

    abstract:BACKGROUND:Spinal arteriovenous malformations (AVM) are an abnormal interconnection of vasculature in the spine than can lead to significant neurologic deficit if left untreated. OBJECTIVE:The objective of this study was to characterize how patients with spinal AVM initially presented, what treatment options were used...

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    authors: Varshneya K,Pendharkar AV,Azad TD,Ratliff JK,Veeravagu A

    更新日期:2019-11-01 00:00:00

  • The Role of Low-Cost Microsurgical Training Models and Experience with Exercises Based on a Bovine Heart.

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    更新日期:2019-10-01 00:00:00

  • The History of Neurosurgery in the Hawaiian Islands.

    abstract::The field of neurosurgery has a rich and fascinating history. The development of the specialty in Hawaii has been particularly unique, given the state's remote location, indigenous population, and military presence. The life of Dr. Ralph B. Cloward, Hawaii's most noted neurosurgeon, has received some attention in the ...

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    pub_type: 传,历史文章,杂志文章,评审


    authors: Swinney C,Obana W

    更新日期:2018-01-01 00:00:00

  • Novel Software-Derived Workflow in Extracranial-Intracranial Bypass Surgery Validated by Transdural Indocyanine Green Videoangiography.

    abstract:BACKGROUND:The introduction of image-guided methods to bypass surgery has resulted in optimized preoperative identification of the recipients and excellent patency rates. However, the recently presented methods have also been resource-consuming. In the present study, we have reported a cost-efficient planning workflow ...

    journal_title:World neurosurgery

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    authors: Dodier P,Auzinger T,Mistelbauer G,Wang WT,Ferraz-Leite H,Gruber A,Marik W,Winter F,Fischer G,Frischer JM,Bavinzski G

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  • Filum Terminale Arteriovenous Fistulas with Multiple Shunt Points: A Report of Two Exceptional Cases.

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    pub_type: 杂志文章


    authors: Hong T,Yu JX,Liu W,Bian LS,Yang F,Ma YJ,Ling F,Zhang HQ

    更新日期:2018-10-01 00:00:00

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    authors: Tsoucalas G,Kousoulis AA,Mariolis-Sapsakos T,Sgantzos M

    更新日期:2017-07-01 00:00:00

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    pub_type: 杂志文章


    authors: Das KK,Gosal JS,Singh S,Mehrotra A,Jaiswal A,Jaiswal S,Kumar R

    更新日期:2017-06-01 00:00:00

  • Primary Hypothyroidism with Exceptionally High Prolactin-A Really Big Deal.

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    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Khorassanizadeh R,Sundaresh V,Levine SN

    更新日期:2016-07-01 00:00:00

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    pub_type: 杂志文章


    authors: Hejrati N,Spieler D,Samuel R,Regli L,Weyerbrock A,Surbeck W

    更新日期:2019-09-01 00:00:00

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    pub_type: 杂志文章


    authors: Sprenger F,de Andrade JMC,de Almeida Teixeira BC

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    authors: Huang L,Zee CS,Zhang XL

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