Neutrophil-to-Albumin Ratio as a Biomarker of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.


OBJECTIVE:This study set out to investigate the relationships between the neutrophil-to-albumin ratio (NAR) in the early stages of aneurysmal subarachnoid hemorrhage (aSAH) and the occurrence of delayed cerebral ischemia (DCI). METHODS:A total of 439 patients with aSAH were included in this retrospective study. NAR assessment was conducted on admission. The relationship between NAR and DCI was analyzed. RESULTS:Eighty-four patients (23.7%) experienced DCI. NAR levels were significantly higher in patients with DCI after aSAH than without DCI (median [interquartile range] 0.350 [0.274-0.406] vs. 0.240 [0.186-0.300]; P < 0.001). NAR levels were correlated with World Federation of Neurological Surgeons (WFNS) grade and modified Fisher (mFisher) grade (r = 0.505 and 0.394, respectively). NAR and mFisher grade were the independent predictors of DCI. Under receiver operating characteristic curve, NAR levels exhibited a significant discriminatory capability (area under the curve [95% confidence interval] 0.812 [0.740-0.823]; P < 0.001). The predictive power of NAR levels was similar to mFisher grade (P > 0.05). CONCLUSIONS:NAR, in positive correlation with the severity of hemorrhage, appears to be a novel predictive biomarker of DCI after aSAH.


World Neurosurg


World neurosurgery


Zhang X,Liu Y,Zhang S,Wang C,Zou C,Li A




Has Abstract


2020-12-26 00:00:00








  • Effects of Modic Type 1 Changes in the Vertebrae on Low Back Pain.

    abstract:OBJECTIVE:The present study examined the physical extent of Modic type 1 (MT1) changes and other phenotypic magnetic resonance imaging (MRI) findings in the vertebrae of patients with low back pain (LBP) and MT1 changes. We also identified any correlations of these findings with the severity of pain and the Oswestry Di...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Hanımoğlu H,Çevik S,Yılmaz H,Kaplan A,Çalış F,Katar S,Evran Ş,Akkaya E,Karaca O

    更新日期:2019-01-01 00:00:00

  • Does Nasal Carriage of Staphylococcus aureus Increase the Risk of Postoperative Infections After Elective Spine Surgery: Do Most Infections Occur in Carriers?

    abstract:BACKGROUND:Wound infections after adult spinal deformity surgery place a high toll on patients, providers, and the healthcare system. Staphylococcus aureus is a common cause of postoperative wound infections, and nasal colonization by this organism may be an important factor in the development of surgical site infectio...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Adogwa O,Vuong VD,Elsamadicy AA,Lilly DT,Desai SA,Khalid S,Cheng J,Bagley CA

    更新日期:2018-08-01 00:00:00

  • Application of Piezosurgery in En Bloc Laminectomy for the Treatment of Multilevel Thoracic Ossification of Ligamentum Flavum.

    abstract:OBJECTIVE:To evaluate safety and effectiveness of the application of piezosurgery in en bloc laminectomy for the treatment of multilevel thoracic ossification of ligamentum flavum (MTOLF). METHODS:Forty-one cases who had MTOLF and underwent en bloc laminectomy from January 2012 to January 2017 were reviewed and divide...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Liu X,Li T,Shi L,Wu Z,Chen D,Xu B,Chen Y

    更新日期:2019-06-01 00:00:00

  • Descriptive epidemiology in relation to gender differences and treatment modalities 10 years after intracranial aneurysm rupture in the Stockholm cohort 1996-1999.

    abstract:OBJECTIVE:To describe epidemiology in relation to gender differences and treatment modalities 10 years after intracranial aneurysm rupture in the Stockholm cohort 1996-1999. METHODS:A total of 468 consecutive patients with aneurysmal subarachnoid hemorrhage were followed-up in a retrospective cohort design 10 years af...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: von Vogelsang AC,Wengström Y,Svensson M,Forsberg C

    更新日期:2013-09-01 00:00:00

  • Ruptured Aneurysm of an Aberrant Internal Carotid Artery Successfully Treated with Simultaneous Intervention and Surgery in a Hybrid Operating Room.

    abstract:BACKGROUND:Aberrant internal carotid artery (aICA) is an anatomic anomaly whereby the internal carotid artery courses through the tympanic cavity without separation by bone. Because aICA is rare, there are no definite treatment strategies for aICA and its complications. CASE DESCRIPTION:We report a case of aICA accomp...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Kawamura Y,Sayama T,Maehara N,Nishimura A,Iihara K

    更新日期:2017-06-01 00:00:00

  • Usefulness of High-Resolution Three-Dimensional Multifusion Medical Imaging for Preoperative Planning in Patients with Cerebral Arteriovenous Malformation.

    abstract:BACKGROUND:Successful resection of arteriovenous malformation (AVM) depends on preoperative assessment of the detailed morphology of the AVM. Simultaneous detailed three-dimensional visualization of the feeding arteries, draining veins, and surrounding structures is needed. The aim of this study was to evaluate the use...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Yoshino M,Kin T,Hara T

    更新日期:2019-01-22 00:00:00

  • Posterior Lumbar Interbody Fusion versus Dynamic Hybrid Instrumentation: A Prospective Randomized Clinical Trial.

    abstract:OBJECTIVE:The purpose of this study was to assess the radiologic and clinical outcomes after lumbar fusion intervention and to compare the established posterior lumbar interbody fusion (PLIF) technique and dynamic hybrid instrumentation (topping off). METHODS:In this prospective randomized trial, all patients who pres...

    journal_title:World neurosurgery

    pub_type: 杂志文章,随机对照试验


    authors: Herren C,Simons RM,Bredow J,Oikonomidis S,Westermann L,Sobottke R,Scheyerer MJ,Pishnamaz M,Eysel P,Zarghooni K,Franklin J,Siewe J

    更新日期:2018-09-01 00:00:00

  • Tuberculum Sellae Meningiomas in Pregnancy: 3 Cases Treated in the Second Trimester and Literature Review.

    abstract:BACKGROUND:Tuberculum sella meningiomas typically present with progressive visual loss. It is also known that meningiomas can become symptomatic during pregnancy. Herein we report on 3 patients who presented with progressive visual decline during pregnancy, prompting urgent surgical removal of their meningiomas. CASE ...

    journal_title:World neurosurgery



    authors: Mallari RJ,Thakur JD,Griffiths C,Krauss H,Eisenberg A,Barkhoudarian G,Kelly DF

    更新日期:2020-11-01 00:00:00

  • Contralateral Hearing Loss After Resection of Vestibular Schwannoma in a Patient with Neurofibromatosis 2: Case Report and Literature Review.

    abstract:BACKGROUND:Resection of a vestibular schwannoma may result in facial paralysis and hearing loss on the side of the tumor. We evaluated clinical, audiologic, and intraoperative events and radiologic parameters in a case of contralateral side sensorineural hearing loss. We also performed a literature search using PubMed....

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Tripathi M,Satapathy A,Chauhan RB,Batish A,Gupta SK

    更新日期:2018-09-01 00:00:00

  • Intraoperative Indocyanine Green-Based Cortical Perfusion Assessment in Patients Suffering from Severe Traumatic Brain Injury.

    abstract:OBJECTIVES:The pathophysiology of traumatic brain injury (TBI) largely involves the brains vascular structural integrity. We analyzed the value of an intraoperative cortical indocyanine green (ICG) angiography in patients with severe TBI and acute subdural hematoma who underwent decompressive craniectomy. METHODS:ICG-...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Kamp MA,Sarikaya-Seiwert S,Petridis AK,Beez T,Cornelius JF,Steiger HJ,Turowski B,Slotty PJ

    更新日期:2017-05-01 00:00:00

  • From planes to brains: parallels between military development of virtual reality environments and virtual neurological surgery.

    abstract::Military explorations of the practical role of simulators have served as a driving force for much of the virtual reality technology that we have today. The evolution of 3-dimensional and virtual environments from the early flight simulators used during World War II to the sophisticated training simulators in the moder...

    journal_title:World neurosurgery

    pub_type: 历史文章,杂志文章


    authors: Schmitt PJ,Agarwal N,Prestigiacomo CJ

    更新日期:2012-09-01 00:00:00

  • Effect of Dexmedetomidine with Different Anesthetic Dosage on Neurocognitive Function in Elderly Patients After Operation Based on Neural Network Model.

    abstract::This paper uses a neural network model to study the protective effect of dexmedetomidine on the anesthesia recovery period and neurocognitive function in elderly patients undergoing radical resection of colorectal cancer. Eighty-eight patients with colorectal cancer who underwent radical surgery in our hospital from J...

    journal_title:World neurosurgery

    pub_type: 杂志文章,随机对照试验


    authors: Chen H,Li F

    更新日期:2020-06-01 00:00:00

  • Application of Midazolam Injection in Patients with Intraoperative Nerve Block Anesthesia and Sedation Assisted by Medical Image.

    abstract::This paper explores the clinical effect of midazolam as an adjuvant analgesic and tranquilizer after brachial plexus block anaesthesia with the aid of medical imaging. The paper selected 106 patients who underwent elective unilateral upper extremity surgery from January 2017 to December 2019, and randomly divided them...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Xu X,Hu X,Han Y,Zhuang X,Tang R,Xu Y

    更新日期:2020-11-26 00:00:00

  • Superficial Temporal Artery-Superior Cerebellar Artery Bypass with Anterior Petrosectomy.

    abstract:BACKGROUND:Superficial temporal artery (STA) to superior cerebellar artery (SCA) bypass is associated with a relatively high risk of surgical complications, such as hematoma and/or edema caused by temporal lobe retraction. Therefore, the right side is typically used to avoid retraction of the left temporal lobe. In thi...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Hokari M,Asaoka K,Shimbo D,Uchida K,Itamoto K

    更新日期:2018-06-01 00:00:00

  • Deep brain stimulation for treatment-resistant depression.

    abstract:BACKGROUND:Major depressive disorder is a common and disabling illness and is the leading cause of disability worldwide. Despite aggressive medical, behavioral, and electroconvulsive therapies, a significant number of patients remain refractory to treatment. Deep brain stimulation (DBS) has proven efficacy in neurobeha...

    journal_title:World neurosurgery

    pub_type: 历史文章,杂志文章,评审


    authors: Taghva AS,Malone DA,Rezai AR

    更新日期:2013-09-01 00:00:00

  • Facial Nerve Neurophysiologic Assessment in Vestibular Schwannoma Removal with Transcanal Approach: A Pilot Clinical Study.

    abstract:BACKGROUND:The transcanal transpromontorial approach has been introduced to remove vestibular schwannomas. As with other techniques, preservation of the facial nerve (FN) is challenging. This pilot study described FN outcomes of patients preoperatively and postoperatively assessed with electromyography (EMG) and blink ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Sacchetto L,Fabbris C,Romito S,Bianconi L,Marchioni D

    更新日期:2020-11-12 00:00:00

  • Intraventricular tumors.

    abstract:OBJECTIVE:To describe the neuroendoscopic technique to deal with intraventricular tumors. METHODS:Details of the endoscopic approach to intraventricular tumors of the lateral, third, and fourth ventricle are presented. RESULTS:Intraventricular tumors are ideal indications for neuroendoscopic surgery. They often cause...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Schroeder HW

    更新日期:2013-02-01 00:00:00

  • Alarming Internal Carotid Artery Aneurysm Eroding the Sphenoid Sinus.

    abstract::In rare instances, extradural internal carotid artery aneurysms can present with massive epistaxis, which is often a fatal event. We present the case of a young female with an aneurysm eroding through the sphenoid sinus and whose timely diagnosis resulted in treatment of the aneurysm with coil embolization and satisfa...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Brasiliense LBC,Dumont TM

    更新日期:2017-12-01 00:00:00

  • Emerging Trends in the Neurosurgical Workforce of Low- and Middle-Income Countries: A Cross-Sectional Study.

    abstract:BACKGROUND:Every year, there are an estimated 22.6 million new neurosurgical consultative cases worldwide, of which 13.8 million require surgery. In 2016, the global neurosurgical workforce was estimated and mapped as open-access information to guide neurosurgeons, affiliates, and policy makers. We present a subsequent...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Kanmounye US,Lartigue JW,Sadler S,Yuki Ip HK,Corley J,Arraez MA,Park K

    更新日期:2020-10-01 00:00:00

  • Antibiotic Prophylaxis in Endoscopic Endonasal Pituitary and Skull Base Surgery.

    abstract:OBJECTIVE:Postoperative infection is a potentially dramatic consequence in endoscopic endonasal surgery. The aim of this study was to assess the efficacy of our intraoperative antibiotic prophylaxis by analyzing the risk factors of postoperative meningitis in our series. METHODS:Each endoscopic endonasal procedure per...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Milanese L,Zoli M,Sollini G,Martone C,Zenesini C,Sturiale C,Farneti P,Frank G,Pasquini E,Mazzatenta D

    更新日期:2017-10-01 00:00:00

  • Treatment of large and giant intracranial aneurysms: cost comparison of flow diversion and traditional embolization strategies.

    abstract:OBJECTIVE:Flow diversion has emerged as a promising strategy for management of intracranial aneurysms. The purpose of this study was to determine whether treatment of large and giant aneurysms with the pipeline embolization device (PED) is more economical than traditional embolization strategies. METHODS:We identified...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: el-Chalouhi N,Jabbour PM,Tjoumakaris SI,Starke RM,Dumont AS,Liu H,Rosenwasser R,El Moursi S,Gonzalez LF

    更新日期:2014-11-01 00:00:00

  • Spontaneous Change in Density of Colloid Cyst: An Unusual Phenomenon.

    abstract:BACKGROUND:Colloid cysts of the third ventricle are benign congenital lesions. They are at times totally asymptomatic or may be detected in the evaluation for headache, neurologic disturbances, or psychiatric disturbances. They may sometimes cause grave consequences such as coma or even sudden death. The radiologic app...

    journal_title:World neurosurgery



    authors: Kutty RK,Balakrishnan Sreemathyamma S,Sivanandapanicker JL,Asher P,Peethambaran A,Nair NG

    更新日期:2020-09-01 00:00:00

  • Time to Event Analysis for the Development of Venous Thromboembolism After Spinal Fusion ≥ 5 Levels.

    abstract:OBJECTIVE:Venous thromboembolism (VTE) is an important complication after spine surgery with an incidence of 31%. To our knowledge, no study has reported a time-dependent examination of factors influencing VTE. We report factors influencing first and multiple VTE events and perform a time-dependent analysis. METHODS:A...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: McClendon J Jr,Smith TR,O'Shaughnessy BA,Sugrue PA,Thompson SE,Koski TR

    更新日期:2015-09-01 00:00:00

  • Harvey Cushing's early treatment of meningiomas: the untold story.

    abstract:BACKGROUND:In his 1938 monograph, Cushing tabulated 313 meningioma cases treated throughout his career at the Johns Hopkins and the Peter Bent Brigham Hospitals. Of these, 18 patients were treated at the Johns Hopkins Hospital. Cushing provided basic demographic, perioperative, and outcomes data in his tables, but the ...

    journal_title:World neurosurgery

    pub_type: 传,历史文章,杂志文章


    authors: Pendleton C,Olivi A,Brem H,Quiñones-Hinojosa A

    更新日期:2013-07-01 00:00:00

  • Effects of Ho:YAG Laser Ablation on Postoperative Low Back Pain and Functional Status After Transforaminal Endoscopic Lumbar Discectomy: Minimum of 2-Year Follow-Up.

    abstract:OBJECTIVE:To evaluate effects of holmium:yttrium-aluminum-garnet (Ho:YAG) laser ablation on postoperative low back pain and improving functional status in patients with lumbar disc herniation undergoing transforaminal endoscopic lumbar discectomy (TELD). METHODS:The study enrolled 220 patients with lumbar disc herniat...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Li Y,Wang B,Lü G,Li L,Dai Y,Tu Z,Gu H

    更新日期:2019-07-01 00:00:00

  • Recurrence of Anterior Skull Base Meningiomas After Endoscopic Endonasal Resection: 10 Years' Experience in a Series of 52 Endoscopic and Transcranial Cases.

    abstract:INTRODUCTION:Although the indication of endoscopic approaches for anterior skull base meningiomas (ASBM) has been progressively refined, there remains a paucity of data on recurrence rates after resection. To analyze and compare recurrence rates of ASBM resected through endoscopic endonasal (EEE) versus transcranial (T...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Bernat AL,Priola SM,Elsawy A,Farrash F,Pasarikovski CR,Almeida JP,Lenck S,De Almeida J,Vescan A,Monteiro E,Zadeh GM,Gentili F

    更新日期:2018-12-01 00:00:00

  • Minimally Invasive Surgical Management of Thoracic Ossification of the Ligamentum Flavum Associated with X-linked Hypophosphatemia.

    abstract:BACKGROUND:X-linked hypophosphatemia (XLH) is the most common inherited form of renal phosphate wasting and inherited rickets. Patients have hyperplasia of fibrochondrocytes in tendons and ligaments, causing the structures to thicken and calcify. Thickening of the lamina, hypertrophy of facet joints, and calcification ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Riccio AR,Entezami P,Giuffrida A,Dowling J,Forrest G,German JW

    更新日期:2016-10-01 00:00:00

  • Island Sign Predicts Long-Term Poor Outcome and Mortality in Patients with Intracerebral Hemorrhage.

    abstract:BACKGROUND:The island sign is a novel imaging predictor for early hematoma growth, implying multifocal active bleeding. The prognostic value of the island sign for long-term outcome in patients with intracranial hemorrhage (ICH) remains unrevealed. The aim of this study is to investigate associations between the island...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Zhang F,Li H,Qian J,Zhang S,Tao C,You C,Yang M

    更新日期:2018-12-01 00:00:00

  • Obese (Body Mass Index >30) Patients Have Greater Functional Improvement and Reach Equivalent Outcomes at 12 Months Following Decompression Surgery for Symptomatic Lumbar Stenosis.

    abstract:OBJECTIVE:To evaluate effect of obesity on 12-month functional outcomes after surgery for lumbar stenosis in adult patients. METHODS:Data were collected on patients treated with lumbar laminectomy for symptomatic lumbar spinal stenosis as part of an observational registry and analyzed using a retrospective cohort stud...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Elsayed G,Davis MC,Dupépé EC,McClugage SG,Szerlip P,Walters BC,Hadley MN

    更新日期:2017-09-01 00:00:00

  • Cranioplasty with Titanium Might Be Suitable for Adult Epilepsy Surgery After Subdural Placement Surgery To Avoid Surgical Site Infection.

    abstract:BACKGROUND:The purpose of the present study was to compare the surgical site infection (SSI) rates between resorbable plates and titanium plates used for adult patients with intractable epilepsy who had undergone epilepsy surgery after subdural electrode placement. METHODS:We performed subdural electrode surgery, foll...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Amano Y,Fujimoto A,Ichikawa N,Sato K,Baba S,Nishimura M,Enoki H,Okanishi T

    更新日期:2019-11-01 00:00:00