Abstract:
:In a single-centre study 59 patients with gastric ulcer were treated either with 300 mg ranitidine at night or with 150 mg ranitidine twice daily. After 4 and 8 weeks 73% and 97%, respectively, of those treated with 300 mg at night and 59% and 86% of those treated with 150 mg twice daily had complete ulcer healing. These differences between the two groups were not statistically significant. No serious side effects were seen. Ranitidine, 300 mg at night, appears to be at least as effective as the standard 150 mg twice daily regimen in the treatment of gastric ulcer.
journal_name
Scand J Gastroenteroljournal_title
Scandinavian journal of gastroenterologyauthors
Jorde R,Burhol PGdoi
10.3109/00365528609011127subject
Has Abstractpub_date
1986-09-01 00:00:00pages
833-6issue
7eissn
0036-5521issn
1502-7708journal_volume
21pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:Hepatic stimulator substance (HSS) is a known hepatic growth factor that appears to be organ-specific but species-nonspecific. In the present study we investigated the effect of HSS administration in a rat model of liver injury and regeneration induced by thioacetamide (TAA) injection. METHODS:TAA (300 mg/k...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365529850171954
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Different concentrations of immunoglobulin G (IgG) subclass-producing cells in the mucosa of patients with ulcerative colitis and Crohn's disease have previously been described. METHODS:To evaluate serum concentration of IgG subclasses as a tool for diagnosis and disease activity in chronic inflammatory bow...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365529509093235
更新日期:1995-01-01 00:00:00
abstract::Gastric and duodenal bulb pH was measured simultaneously with a multiple pH electrode system in 15 duodenal ulcer patients. A single dose of 10 ml antacid was given 120 min after a liquid standard meal, and the pH was measured for another 90 min. The effect of antacid on duodenal pH, expressed as the time pH is kept a...
journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章
doi:10.3109/00365528809090150
更新日期:1988-10-01 00:00:00
abstract::Twenty-nine patients with attacks of distal ulcerative colitis were treated randomly with 3 g 5-aminosalicylic acid (5-ASA) or 30 mg of prednisolone phosphate sodium (PP) enemas (40 ml). Endoscopic, clinical, and histologic improvement were comparable in the two treatment groups. Our study showed that topical treatmen...
journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00365528809090161
更新日期:1988-10-01 00:00:00
abstract:BACKGROUND:This study was designed to evaluate the results of electrostimulation of the pelvic floor for faecal incontinence. METHODS:Twenty-four patients with neurogenic (n = 20) or idiopathic (n = 4) incontinence were treated on 12 occasions. Twenty were women, and the mean age was 63 years (range, 26-85 years). The...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365529950173762
更新日期:1999-03-01 00:00:00
abstract::The association between macroamylasaemia and coeliac disease in Down syndrome with multiple autoimmune abnormalities has never been reported. A 40-year-old woman with a 15-year history of immunoglobulin A and immunoglobulin M hypergammaglobulinaemia, chronic diarrhoea, persistent mild aspartate aminotransferase (AST) ...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365520310000933
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to identify the predictive factors influencing mortality in patients with bleeding Mallory-Weiss syndrome in comparison with peptic ulcer bleeding. MATERIAL AND METHODS:Between January 2005 and December 2009, 281 patients with endoscopically confirmed Mallory-Weiss syndrome and 1530...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章,多中心研究
doi:10.3109/00365521.2013.846404
更新日期:2014-04-01 00:00:00
abstract::We report a rare case of Crohn disease accompanied by a small-bowel carcinoma that developed in a 54-year-old Japanese man. The ulcerating tumor, which histologically proved to be a poorly differentiated adenocarcinoma and dysplasia surrounding the carcinoma, was located in the diseased ileum. The Ki-67 immunoreactive...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/003655299750024995
更新日期:1999-11-01 00:00:00
abstract::Changes in urinary PGE2 and PGF2 alpha excretion in chronic liver diseases were observed in relation to renal hemodynamics and sodium balance. After equilibration on a 110-170-meq sodium diet, daily urine collections were analyzed for PGE2 and PGF2 alpha by a new extraction and radioimmunoassay method. PGE2 was signif...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528609034626
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:The potential role of superantigens in inflammatory bowel disease (IBD), particularly Crohn disease, has been broached in studies of the functions of T cell receptors. Staphylococcal cells have been found in intestinal lymph follicles of IBDs. To clarify a role of staphylococcal superantigens in IBD, we atte...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/003655201750163079
更新日期:2001-06-01 00:00:00
abstract::Eighty-seven patients with endoscopically healed duodenal ulcers received continuous maintenance treatment with a standard dose of 150 mg ranitidine at night for 6-12 months. The cumulative annual rate of symptomatic reulceration was 24%, whereas a further 25% of asymptomatic relapses were detected with routine endosc...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528309181583
更新日期:1983-03-01 00:00:00
abstract::During the period 1984-87, 472 patients with histologically or cytologically verified carcinoma of the pancreas (n = 442) or the papilla of Vater (n = 30) were accrued. Diagnostic investigations were performed in accordance with the ordinary routines of 38 Norwegian hospitals. Jaundice at presentation, found in 47% of...
journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/00365529209000081
更新日期:1992-04-01 00:00:00
abstract:BACKGROUND:Increased faecal calprotectin shedding indicates gastrointestinal mucosal inflammation. METHODS:We studied the effect of short-term treatment with non-steroidal anti-inflammatory drugs (NSAIDs) on faecal calprotectin shedding in two randomized crossover studies, with treatment regimens of indomethacin or na...
journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00365529609006407
更新日期:1996-04-01 00:00:00
abstract:OBJECTIVE:The mechanisms of action of infliximab (IFX) in the treatment of ulcerative colitis (UC) are poorly understood. The aim of the study was to investigate the changes in tissue expression of tumor necrosis factor-alpha (TNF-alpha) and other cytokines in UC patients receiving IFX treatment. MATERIAL AND METHODS:...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365520902803507
更新日期:2009-01-01 00:00:00
abstract::In 14 patients with alcoholic hepatitis an echographic study of the gallbladder was carried out. Nine subjects showed gallbladder wall thickening (thickness greater than 4 mm) and two a 'scanty content gallbladder'. These findings did not correlate with the serum albumin levels. The authors point out the similarity of...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528708991891
更新日期:1987-06-01 00:00:00
abstract::The faecal output of chloride, sodium and potassium was studied in 14 patients with active idiopathic proctocolitis, in an attempt to establish a relationship between faecal electrolyte output and acid-base balance data. 7 patients with ileostomy and 8 healthy volunteers were used as controls. The daily faecal excreti...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365527809179829
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:The DNA mismatch repair gene mutations underlying hereditary non-polyposis colorectal cancer syndrome (HNPCC) also predispose, besides colorectal and endometrial cancer, to gastric cancer. usually of the intestinal type. The carcinogenetic pathway behind the elevated gastric cancer risk is largely unknown. ...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365520252903134
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:Lynch syndrome (LS) has an autosomal dominant inheritance pattern and is associated with increased risk for colorectal cancer (CRC) and other cancers. Various strategies are used to identify patients at risk and offer surveillance and preventive programs, the cost effectiveness of which is much dependent on t...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章,多中心研究
doi:10.1080/00365521.2018.1542453
更新日期:2018-12-01 00:00:00
abstract::Background: Neuroendocrine tumours (NETs) in the ileum grow slowly but metastasise to the liver at an early stage. After resection of the primary tumour and mesenteric lymph nodes, selected patients with liver metastases have been operated with curative intention. Recurrence-free survival seems low, suggesting that mi...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365521.2019.1647281
更新日期:2019-08-01 00:00:00
abstract::The reproducibility of simultaneous, long-term, ambulatory gastric pH recordings in the antrum and corpus was investigated in nine healthy subjects who underwent three separate, 27-h gastric double pH-metries. Intraindividual reproducibility for the entire 27-h recording period was good in the corpus (Kendall's concor...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365529008997637
更新日期:1990-10-01 00:00:00
abstract:BACKGROUND:Serum leptin levels are elevated in alcoholic liver cirrhosis and thus might be involved in the anorexia and hypermetabolism often seen in those patients. We hypothesized that the leptin system is modulated in patients with hepatitis C and might be affected by antiviral therapy. The aim of this study was to ...
journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章
doi:10.1080/003655201300051333
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:Multichannel intraluminal impedance and manometry (MII-EM) is performed using ten 5-ml swallows each of a liquid and a viscous solution. However, the manometric diagnosis is based solely on results from the 10 liquid swallows. The aim of this study was to compare esophageal function evaluated with 10 liquid v...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365520701245702
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Topical treatment is effective in patients with distal ulcerative colitis. This trial compares the efficacy, safety, and practicality of 4 weeks' treatment with 500 mg mesalazine suppositories with those of 178 mg hydrocortisone foam, both given twice daily. METHODS:Seventy-nine patients with distal ulcerat...
journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.3109/00365529509093256
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:Acute liver failure (ALF) is haemodynamically characterized by a hyperdynamic circulation. The aims of this study were to investigate the systemic and regional haemodynamics in ALF, to measure changes in nitric oxide metabolites (NOx) and to evaluate whether these haemodynamic disturbances could be attenuated...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/00365520600714527
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:We evaluated the reliability and usefulness of the 14C urea breath test (UBT) in confirming eradication of Helicobacter pylori 4 to 6 weeks after cessation of antimicrobial therapy. METHODS:We investigated 57 patients, who underwent both an upper endoscopy with multiple biopsy specimens taken for histopatho...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365529709000180
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:Patients with coeliac disease have low bone mineral density (BMD), but the underlying mechanisms are unclear. Our aim was to study circulating insulin-like growth factor I (IGF-I) and its possible relationship to BMD in adults with untreated coeliac disease and after 1 year on a gluten-free diet. METHODS:In...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.1080/003655299750025381
更新日期:1999-09-01 00:00:00
abstract::The reproducibility of measuring 3-day faecal fat and weight in outpatients, in inpatients served a fixed diet, and in intake-excretion studies was estimated from 64 duplicate measurements. Qualitatively, no significant difference between the results of the three regimens was found. Quantitatively, however, the more c...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:
更新日期:1984-05-01 00:00:00
abstract::Parietal cell regeneration in cauterized gastric wounds was studied in rats after antrectomy (Billroth I), pyloroplasty, and truncal vagotomy with pyloroplasty. Six to eight animals in each group were killed 90 or 130 days after operation, and in each rat stereological data were obtained from electron micrographs of 1...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528309182106
更新日期:1983-10-01 00:00:00
abstract::In a 5-year clinicopathological study of acute colitis involving 238 adults, 42 patients were found to have 'transient colitis syndrome'. This is a term we have developed to describe those patients who have a short-duration self-limiting acute colitis of abrupt onset and negative bacteriology and which does not recur....
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528209181107
更新日期:1982-10-01 00:00:00
abstract::It has been suggested that the symptoms of flatulent dyspepsia are caused by a functional disturbance of the upper gastrointestinal tract. The aim of this study was to investigate delayed gastric emptying as the basis of symptoms in patients with and without gallbladder disease and after cholecystectomy. There were 13...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528708991855
更新日期:1987-01-01 00:00:00