Prednisolone and posttransplantation hypertension in rat renal allograft recipients.

abstract：:The potent immunosuppressive action of rabbit antithymocyte globulin (RATG) in allotransplant recipients has been recognized for many years. Some of the antibody specificities and immunoregulatory effects of RATG have been described, but a comprehensive definition of RATG components has not been reported previously. I...

journal_title：Transplantation

authors： Rebellato LM,Gross U,Verbanac KM,Thomas JM

更新日期：1994-03-15 00:00:00

abstract：BACKGROUND:To evaluate the long-term outcome of renal transplant patients with membranoproliferative glomerulonephritis (MPGN) type I and the impact of recurrence. METHODS:The outcomes of 68 renal transplants performed between 1976 and 2009 in 63 patients with MPGN were compared with those of 136 controls matched for ...

journal_title：Transplantation

authors： Moroni G,Casati C,Quaglini S,Gallelli B,Banfi G,Montagnino G,Messa P

更新日期：2011-06-15 00:00:00

abstract：:Hemorrhagic cystitis (HC) is a major cause of morbidity after BMT; we have analyzed its incidence, risk factors, and complications in 977 patients undergoing BMT between 1974 and 1988. Despite vigorous hydration and frequent voiding in all patients receiving cyclophosphamide, 135/977 (15% by Kaplan-Meier projection) d...

journal_title：Transplantation

authors： Sencer SF,Haake RJ,Weisdorf DJ

更新日期：1993-10-01 00:00:00

abstract：:Allogeneic lymphocyte cytotoxicity (ALC) describes the elimination of allogeneic lymphocytes in vivo by an NK-related activity. There is evidence that ALC is demonstrable between donor and recipient when these are incompatible at MHC gene loci alone. Since ALC is a property of T cell-deficient nude rats, the role of t...

journal_title：Transplantation

authors： Ager A,Fajumi J,Sparshott SM,Ford WL,Butcher GW

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:We examined whether oral administration of alloantigen could induce the prolonged survival of cardiac allografts. METHODS:Hearts from CBK (H2k+Kb) transgenic or (C57BL/10xCBA)F1 (H2bxH2k) mice were transplanted into CBA (H2k) recipients pretreated orally with 1 x 10(7) donor splenocytes in the presence or a...

journal_title：Transplantation

authors： Niimi M,Witzke O,Bushell A,Hara M,Morris PJ,Wood KJ

更新日期：2000-11-27 00:00:00

abstract：BACKGROUND:The established method of pretransplant cross-matching does not detect IgA antibodies, and IgA antibodies have thus been ignored when assessing patients for transplantation. The aim of this study was to detect IgA allo- and autoreactive antibodies using flow cytometry and to correlate the results with transp...

journal_title：Transplantation

authors： Doran TJ,Süsal C,Opelz G,Geczy AF

更新日期：1999-01-27 00:00:00

abstract：:India with a population of 1.2 billion has a renal transplantation rate of 3.25 per million population. The major cause of chronic kidney disease is hypertension and diabetes. The crude and age-adjusted incidence rates of end-stage renal disease are estimated to be 151 and 232 per million population, respectively, in ...

journal_title：Transplantation

authors： Abraham G,Reddy YN,Amalorpavanathan J,Daniel D,Roy-Chaudhury P,Shroff S,Reddy Y

更新日期：2012-04-27 00:00:00

abstract：:Since major histocompatibility (MHC) antigen matching was introduced in the early 1970s as the key factor determining kidney transplant allocation, several studies, mainly arising from organ-sharing organizations in the United States and Europe, have debated this complex issue. The first fundamental concern is the int...

journal_title：Transplantation

authors： Hiesse C,Pessione F,Houssin D

更新日期：2004-02-27 00:00:00

abstract：:Despite previous attempts there is currently no suitable animal model available for xenogeneic graft versus host disease (XGVHD) mediated via human immunocompetent cells. Recently, we have developed an efficient protocol to engraft SCID mice with human peripheral blood lymphocytes (Hu-PBLs). The engraftment efficiency...

journal_title：Transplantation

authors： Sandhu JS,Gorczynski R,Shpitz B,Gallinger S,Nguyen HP,Hozumi N

更新日期：1995-07-27 00:00:00

abstract：:Following liver transplantation bile formation may be influenced by hepatic denervation and cyclosporine therapy. To better establish any effect of liver transplantation on bile secretion, 6 mongrel dogs were studied: 3 underwent liver denervation by a modified autotransplantation procedure and insertion of a Thomas c...

journal_title：Transplantation

authors： Sutherland FR,Preshaw RM,Shaffer EA

更新日期：1993-02-01 00:00:00

abstract：:Pregnancy in inbred mice is associated with long-term accceptance of H-Y-incompatible skin grafts (in some "rejector" strain females) and with the formation of cytotoxic and agglutinating H-Y antibodies (in females generally). Yet there is no evident correlation between the two phenomena; postpartum females of nonreje...

journal_title：Transplantation

authors： Krupen-Brown K,Wachtel SS

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:There are limited data on the outcome of transplant recipients with familial Mediterranean fever (FMF)-associated AA amyloidosis. The aim of the present study is to evaluate demographic, clinical, laboratory, and prognostic characteristics and outcome measures of these patients. METHODS:Eighty-one renal tra...

journal_title：Transplantation

authors： Sarihan I,Caliskan Y,Mirioglu S,Ozluk Y,Senates B,Seyahi N,Basturk T,Yildiz A,Kilicaslan I,Sever MS

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:In a pilot trial we evaluated the toxicity and efficacy of sirolimus (rapamycin) as second-line therapy for the treatment of acute graft-versus-host disease (GVHD) in 21 patients (1-46 years of age) after allogeneic hematopoietic stem cell transplantation (HSCT). METHODS:All patients were treated with methy...

journal_title：Transplantation

authors： Benito AI,Furlong T,Martin PJ,Anasetti C,Appelbaum FR,Doney K,Nash RA,Papayannopoulou T,Storb R,Sullivan KM,Witherspoon R,Deeg HJ

更新日期：2001-12-27 00:00:00

abstract：BACKGROUND:The impact of the age of the donor on the outcome of living related liver transplantation is yet to be clarified. METHODS:During October 14, 1996 and December 20, 1999, 34 living related liver transplantations were performed. Of these, 26 cases were performed using the extended left lobe graft, which were c...

journal_title：Transplantation

authors： Ikegami T,Nishizaki T,Yanaga K,Shimada M,Kishikawa K,Nomoto K,Uchiyama H,Sugimachi K

更新日期：2000-12-27 00:00:00

abstract：BACKGROUND:Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a distinct form of glomerulonephritis that often recurs after kidney transplantation causing severe graft injury and often failure. METHODS:We describe post transplant outcomes and response to therapy in 20 recipients with ...

journal_title：Transplantation

authors： Buxeda A,Said SM,Nasr SH,Leung N,El Ters M,Cosio FG

更新日期：2019-07-01 00:00:00

abstract：:A mouse monoclonal antibody (CIA) produced against human Ia antigens that reacts with 20-30% of human peripheral blood lymphocytes was found to react with more than 90% of dog lymphocytes. Less than 41% of the Ia-positive dog lymphocytes expressed surface immunoglobulins. Immunoprecipitation studies with 125I-labeled ...

journal_title：Transplantation

authors： Iwaki Y,Terasaki PI,Kinukawa T,Thai TH,Root T,Billing R

更新日期：1983-08-01 00:00:00

abstract：:In the present study the functional and morphologic effects of two pulmoplegic solutions are evaluated. Single left-lung allotransplantation with ligation of the right pulmonary artery was performed in 15 piglets (13-20 kg). The lungs were preserved after donor prostaglandin E-1 treatment with single pulmonary artery ...

journal_title：Transplantation

authors： Lehtola A,Harjula A,Heikkilä L,Hämmäinen P,Taskinen E,Kurki T,Salmenperä M,Mattila S

更新日期：1990-06-01 00:00:00

abstract：:Intercellular adhesion molecule-1 (ICAM-1) induction on hepatocytes was investigated in relation to acute liver allograft rejection, CMV infection, and systemic bacterial infections. Twenty-four liver transplant recipients underwent an episode of acute rejection, 13 developed a symptomatic clinical CMV infection, and ...

journal_title：Transplantation

authors： Lautenschlager IT,Höckerstedt KA

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The first generic tacrolimus product gained Food and Drug Administration approval in August 2009. This prospective, observational trial sought to determine the need for dose titrations and measure drug cost savings on conversion to generic tacrolimus. METHODS:Transplant recipients on stable tacrolimus doses...

journal_title：Transplantation

authors： McDevitt-Potter LM,Sadaka B,Tichy EM,Rogers CC,Gabardi S

更新日期：2011-09-27 00:00:00

abstract：:Eight patients with chronic myeloid leukemia relapse after allogeneic BMT were treated with IFN-alpha and buffy coat transfusions (BC) of the bone marrow donor. The antileukemic effect of this treatment was directly demonstrated in 4 patients by the disappearance of Philadelphia chromosome-positive metaphases or the l...

journal_title：Transplantation

authors： Hertenstein B,Wiesneth M,Novotny J,Bunjes D,Stefanic M,Heinze B,Hübner G,Heimpel H,Arnold R

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The autonomic storm accompanying brain death leads to neurogenic pulmonary edema and triggers development of systemic and pulmonary inflammatory responses. Neurogenic vasoplegia exacerbates the pulmonary injury caused by brain death and primes the lung for ischemia reperfusion injury and primary graft dysfun...

journal_title：Transplantation

authors： Rostron AJ,Avlonitis VS,Cork DM,Grenade DS,Kirby JA,Dark JH

更新日期：2008-02-27 00:00:00

abstract：BACKGROUND:Arterial hypertension (HT) is common in renal transplant recipients (RTRs). Control of HT is not optimal in this high-risk population despite recommendations for target blood pressure levels under 130/80 mm Hg. METHODS:We performed a cross-sectional analysis of the prevalence of uncontrolled HT, and using a...

journal_title：Transplantation

authors： Vetromile F,Pernin V,Szwarc I,Garrigue V,Delmas S,Mourad G,Fesler P

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether screening for anti-human leukocyte antigen (HLA) antibodies (Abs) could predict development of acute rejection (AR) before clinical evidence of kidney allograft dysfunction in nonsensitized recipients. METHODS:Eighty-four non-HLA identical kidney transplant...

journal_title：Transplantation

authors： Gill JS,Landsberg D,Johnston O,Shapiro RJ,Magil AB,Wu V,Tinckam K,Keown P

更新日期：2010-01-27 00:00:00

abstract：BACKGROUND:Preemptive therapy of human cytomegalovirus (HCMV) infections has gained popularity in transplantation centers. However, standardized protocols are not available. In particular, whether a qualitative molecular assay for detection of a late (pp67) HCMV mRNA represents a valuable alternative to quantitative an...

journal_title：Transplantation

authors： Gerna G,Baldanti F,Lilleri D,Parea M,Torsellini M,Castiglioni B,Vitulo P,Pellegrini C,Viganò M,Grossi P,Revello MG

更新日期：2003-04-15 00:00:00

abstract：BACKGROUND:Although islet xenotransplantation is a promising therapy for type 1 diabetes, its clinical application has been hampered by cellular rejection and the requirement for high levels of immunosuppression. The aim of this study was to determine the role of Foxp3 regulatory T (Treg) cells in costimulation blockad...

journal_title：Transplantation

authors： Wu J,Hu M,Qian YW,Hawthorne WJ,Burns H,Liuwantara D,Alexander SI,Yi S,O'Connell PJ

更新日期：2017-07-01 00:00:00

abstract：:To determine the extent to which pretransplant immunity resulting from natural infection protects against cytomegalovirus (CMV) disease, we analyzed CMV serology on 153 kidney donor and recipient pairs and followed transplant patients to determine incidence and severity of CMV disease. The overall incidence of CMV dis...

journal_title：Transplantation

authors： Smiley ML,Wlodaver CG,Grossman RA,Barker CF,Perloff LJ,Tustin NB,Starr SE,Plotkin SA,Friedman HM

更新日期：1985-08-01 00:00:00

abstract：:Experiments were performed on the quality of renal functional recovery after 24, 48, or 72-hr hypothermic storage preservation of canine kidneys in Euro-Collins solution (EC), Collins' solution C2, hypertonic citrate solutions (HC, HC-D2O), or our new flush solution 2 (F.2). Clearance tests (inulin, paraaminohippuric ...

journal_title：Transplantation

authors： Fischer JH,Knupfer P,Beyer M

更新日期：1985-02-01 00:00:00

abstract：:A total of 159 patients received renal cadaveric grafts under 2 different allocation systems. System 1, a local variance (i.e., a point system different from that of United Network for Organ Sharing [UNOS]), and system 2, the current UNOS point system, differed in the relative emphasis on waiting time and HLA match. T...

journal_title：Transplantation

authors： Zachary AA,Braun WE,Hayes JM,McElroy JB,Novick AC,Schulak JA,Sharp WV

更新日期：1994-04-15 00:00:00

abstract：BACKGROUND:Waiting time to deceased donor kidney transplant varies greatly across the United States. This variation violates the final rule, a federal mandate, which demands geographic equity in organ allocation for transplantation. METHODS:Retrospective analysis of the United States Renal Data System and United Netwo...

journal_title：Transplantation

authors： Davis AE,Mehrotra S,McElroy LM,Friedewald JJ,Skaro AI,Lapin B,Kang R,Holl JL,Abecassis MM,Ladner DP

更新日期：2014-05-27 00:00:00

abstract：:The current shortage of donor organs has stimulated investigation of pig-to-human xenotransplantation as a practical alternative to allotransplantation. However, a major obstacle to this xenotransplantation is hyperacute rejection, which is believed to be initiated by the interaction of natural anti-alpha-galactosyl (...

journal_title：Transplantation

authors： Li SF,Neethling FA,Taniguchi S,Yeh JC,Kobayashi T,Ye Y,Koren E,Cummings RD,Cooper DK

更新日期：1996-11-15 00:00:00