Vertebral bone mineral analysis: an integrated approach with CT.

Abstract:

:In the assessment of vertebral bone mineral density (BMD) with quantitative computed tomography, accuracy is limited by systematic errors caused by beam-hardening effects and unknown marrow and fat concentrations in trabecular bone. Reproducibility depends on precise repositioning of the patient, selection of the region of interest (ROI), and apparatus stability. In an integrated approach, these error sources were taken into account. Dual-energy methods are incorporated and tested to avoid systematic errors. Contour-detection algorithms for automated ROI determination that work reliably and offer improved reproducibility and efficiency are presented. A new design of reference phantom with solid tissue-equivalent materials provides calibration in BMD units and checks apparatus stability. Dual-energy methods are necessary to achieve accuracy of 5% or better. Automated ROI definition and reference phantom methods are mandatory for reproducibility of 2% or better.

journal_name

Radiology

journal_title

Radiology

authors

Kalender WA,Klotz E,Suess C

doi

10.1148/radiology.164.2.3602380

subject

Has Abstract

pub_date

1987-08-01 00:00:00

pages

419-23

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

164

pub_type

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