Abstract:
PURPOSE:To investigate and describe the anatomic distribution, imaging features, and pattern of metastatic spread of malignant gastrointestinal stromal tumors (GISTs). MATERIALS AND METHODS:The medical records of all patients at our institution with a histologic diagnosis of GIST were reviewed. Two radiologists with knowledge of the diagnosis reviewed the radiologic findings by means of consensus. Sixty-seven patients underwent computed tomography, and scans of the primary tumor were available in 38 patients. RESULTS:One hundred sixteen patients with malignant GISTs were identified (76 men and 40 women; mean age, 54.6 years +/- 13.5 [SD]). The primary tumor locations in descending order of frequency were the small bowel (n = 49), stomach (n = 43), colon (n = 7), rectum (n = 6), other (n = 3), and not specified (n = 8). Mean primary tumor size was 13 cm +/- 6. Tumors were typically well defined (31 of 36 [86%]), with a heterogeneous rim of soft tissue with lower signal intensity than that of the contrast material-enhanced liver. Central fluid attenuation was seen in 24 of 36 (67%) patients. Metastases were seen in 23 of 38 (61%) patients at presentation and in 53 of 61 (87%) patients during follow-up. Spread was usually to the liver or peritoneum. Visceral obstruction rarely occurred, even in the presence of extensive peritoneal metastatic disease. Ascites was an unusual finding. CONCLUSION:Malignant GISTs are typically large, well-circumscribed, heterogeneous, centrally necrotic tumors that arise in the wall of the small bowel or stomach. They rarely obstruct viscera, despite their large size and propensity to metastasize to the liver and peritoneum.
journal_name
Radiologyjournal_title
Radiologyauthors
Burkill GJ,Badran M,Al-Muderis O,Meirion Thomas J,Judson IR,Fisher C,Moskovic ECdoi
10.1148/radiol.2262011880subject
Has Abstractpub_date
2003-02-01 00:00:00pages
527-32issue
2eissn
0033-8419issn
1527-1315journal_volume
226pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract:PURPOSE:To prospectively determine if kinematic magnetic resonance (MR) imaging of the knee may demonstrate displacement of menisci with tears and, if so, to characterize displaceable and nondisplaceable meniscal tears. MATERIALS AND METHODS:The study was approved by the hospital's review board, and informed consent w...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2381041234
更新日期:2006-01-01 00:00:00
abstract::Of the 67-Ga scans obtained in 42 patients with fever and suspected inflammatory lesions, 17 were positive. In 9 patients the scans yielded information about localized inflammation not provided by previous studies. Four patients did not have an inflammatory lesion at the positive site. Ten of 13 abscesses or inflamed ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/116.2.383
更新日期:1975-08-01 00:00:00
abstract::A retrospective study involving 498 women with a total of 666 breast lesions was undertaken to determine the relative efficacy of one- and two-view mammography in the follow-up evaluation of "low-suspicion" abnormal mammographic findings. These abnormalities consisted of well-defined masses (47.1%), well-defined punct...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.180.2.2068300
更新日期:1991-08-01 00:00:00
abstract:PURPOSE:To explore the neural correlates of the thalamus by using resting-state functional magnetic resonance (MR) imaging and to investigate whether thalamic resting-state networks (RSNs) are disrupted in patients with mild traumatic brain injury (MTBI). MATERIALS AND METHODS:This HIPAA-compliant study was approved b...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11110014
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To develop a three-dimensional (3D) segmentation and computerized volumetry technique for use in the assessment of neurofibromatosis and to assess the ability of this technique to aid in the calculation of tumor burden in patients with neurofibromatosis types 1 and 2 (NF1 and NF2, respectively) and schwannomato...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2503080700
更新日期:2009-03-01 00:00:00
abstract::Extracorporeal shock wave lithotripsy (ESWL), either alone or in combination with percutaneous or retrograde techniques, has rapidly become the procedure of choice for the treatment of intrarenal and upper ureteral calculi. Complications have been few so far and usually have been urinary obstructions or hemorrhages. M...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.163.3.3575710
更新日期:1987-06-01 00:00:00
abstract:PURPOSE:To determine the composition of a breast phantom that is most suitable for phototimer testing. MATERIALS AND METHODS:Kilovolt peak and milliampere second values were analyzed for phototimed exposures of phantoms containing 0%, 30%, 50%, 70%, and 100% simulated glandular material at thicknesses of 2, 4, 6, and ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.198.2.8596830
更新日期:1996-02-01 00:00:00
abstract::The radionuclide, radiographic and pathologic findings in a patient with progressive multifocal leukoencephalopathy were correlated. Radionuclide imaging demonstrated the largest two of the many lesions observed at pathology. On repeated studies, one of the lesions developed a "doughnut" sign due to central necrosis. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/119.2.399
更新日期:1976-05-01 00:00:00
abstract::Prospective data were collected on complications associated with intraarterial digital subtraction angiography in 2,475 consecutive patients at a 650-bed Melbourne teaching hospital. Carotid or cerebral studies were performed in 939 patients, and the prevalence of stroke (ie, permanent neurologic deficit) was 0.3%. Th...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.182.1.1727290
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:To evaluate the diagnostic performance of gray-scale ultrasonography (US) and elastography in differentiating benign and malignant thyroid nodules. MATERIALS AND METHODS:This was an institutional review board-approved retrospective study with waiver of informed consent. A total of 703 solid thyroid nodules in ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11110839
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To prospectively investigate the effect of low tube voltage on radiation dose, contrast enhancement, image quality, and image noise at abdominal dynamic computed tomography (CT). MATERIALS AND METHODS:The institutional review board approved this study. Prior informed consent was obtained from all patients. For...
journal_title:Radiology
pub_type: 杂志文章,随机对照试验
doi:10.1148/radiol.2373041655
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:To develop a method to assess volumetric cortical bone porosity in clinically practical acquisition times by measuring the signal decay at only two echo times (TEs) as part of a single three-dimensional ultrashort TE (UTE) magnetic resonance (MR) examination. MATERIALS AND METHODS:The study was approved by the...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.15141850
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To examine whether the different appearances of intramedullary high signal intensity (SI) on T2-weighted MR images in cervical spondylotic myelopathy are related to differences in surgical prognosis. MATERIALS AND METHODS:The magnetic resonance (MR) findings and Japanese Orthopedic Association (JOA) score of 6...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2213010365
更新日期:2001-12-01 00:00:00
abstract::Purpose To determine whether gadolinium deposits in neural tissues of patients with intracranial abnormalities following intravenous gadolinium-based contrast agent (GBCA) exposure might be related to blood-brain barrier integrity by studying adult patients with normal brain pathologic characteristics. Materials and M...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2017161595
更新日期:2017-11-01 00:00:00
abstract::Background The hardware and software differences between MR vendors and individual sites influence the quantification of MR spectroscopy data. An analysis of a large data set may help to better understand sources of the total variance in quantified metabolite levels. Purpose To compare multisite quantitative brain MR ...
journal_title:Radiology
pub_type: 杂志文章,多中心研究
doi:10.1148/radiol.2020191037
更新日期:2020-04-01 00:00:00
abstract::Tarsal navicular stress fractures are a potential source of disabling foot pain in physically active individuals. The diagnosis of tarsal navicular stress fracture requires a high index of clinical and radiographic suspicion because the fracture is only rarely evident on routine radiographs or standard tomograms. The ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.148.3.6224230
更新日期:1983-09-01 00:00:00
abstract:PURPOSE:To assess the accuracy of glomerular filtration rate (GFR) measurements obtained with low-contrast agent dose dynamic contrast material-enhanced magnetic resonance (MR) renography in patients with liver cirrhosis who underwent routine liver MR imaging, with urinary clearance of technetium 99m ((99m)Tc) pentetic...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11101338
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To determine if wrist arthrography changes surgeons' diagnoses and treatment plans for patients with chronic wrist pain. MATERIALS AND METHODS:Bilateral, three-compartment wrist arthrography was performed in 64 patients. Prospective questionnaires evaluated surgeons' diagnoses and management plans at three sta...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.200.3.8756940
更新日期:1996-09-01 00:00:00
abstract::Twenty-five patients, each of whom had peripheral intrathoracic lesions that were smaller than 5.0 X 5.0 cm in size and not diagnosed by conventional methods, underwent real-time sonography and ultrasonically guided aspiration biopsy. The lesions included 18 nodules, two infiltrates, and five cavitary lesions. Sonogra...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.155.2.3885310
更新日期:1985-05-01 00:00:00
abstract::An 11-year experience with 2,029 outpatient arteriograms in a 500-bed community hospital with active vascular and cardiovascular services is reported. During this period 3,864 inpatient arteriograms were also obtained. The major complication rate has been lower for the outpatient procedures than for the inpatient proc...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.153.2.6435170
更新日期:1984-11-01 00:00:00
abstract:PURPOSE:To examine relationships between brain white matter hyperintensities depicted at magnetic resonance (MR) imaging and performance on neuropsychologic tests in community-dwelling elderly adults. MATERIALS AND METHODS:The 1921 Aberdeen Birth Cohort is a subsample of survivors of the Scottish Mental Survey of 1932...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2211010086
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To evaluate the accuracy of technetium-99m sestamibi as a single agent in the detection and localization of hyperfunctioning parathyroid tissue in patients who underwent prior neck exploration or who otherwise are high surgical risks. MATERIALS AND METHODS:Thirty-nine patients with hyperparathyroidism underwen...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.197.3.7480730
更新日期:1995-12-01 00:00:00
abstract::The authors performed sympathetic nerve blockades in seven patients with peripheral ischemia and possible autonomic dysfunction. Magnetic resonance (MR) imaging was used to guide needle placement, to monitor distribution of injected agents, and to measure increases in blood flow, which were as much as 10-fold. MR imag...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2231010751
更新日期:2002-05-01 00:00:00
abstract::Few reports have described the nature of the appearance of nonacute subdural hematoma on magnetic resonance (MR) images. The authors analyzed MR images in 39 cases of nonacute subdural hematoma and subdural effusion by measuring in vitro proton relaxation times and the biochemical variables of hematoma fluids. T1 beca...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.171.2.2704810
更新日期:1989-05-01 00:00:00
abstract:PURPOSE:To investigate contralateral breast biopsy histologic findings in women with breast cancer. MATERIALS AND METHODS:Histologic findings in 237 patients with breast cancer who underwent contralateral breast biopsy for clinically or mammographically detected abnormalities were retrospectively reviewed. Malignant f...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.203.3.9169690
更新日期:1997-06-01 00:00:00
abstract::Vaginal agenesis was studied by magnetic resonance (MR) imaging lin a 15-year-old girl, a 19-year-old woman, and a 21-year-old woman. In each case MR studies demonstrated the presence or absence of a normal cervix and functioning endometrium. This information was useful in planning surgical management. MR imaging assi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.162.3.3809480
更新日期:1987-03-01 00:00:00
abstract::Fifty consecutive patients with suspected herniated nucleus pulposus at L4-5 or L5-S1 were evaluated prospectively with both epidural venography and iophendylate myelography. The two procedures were compared with respect to diagnostic accuracy, ease of performance, and complications. Evaluation of both the L4-5 and L5...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.134.1.7350590
更新日期:1980-01-01 00:00:00
abstract::Six opossums were evaluated as a possible animal model of radiation esophagitis. In a single exposure to the esophagus, four animals received 60Co radiation of various doses; two served as controls. Pre- and postirradiation evaluations using fiberoptic endoscopy, mucosal biopsy, barium esophagography, and manometry we...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/131.3.731
更新日期:1979-06-01 00:00:00
abstract::Purpose To determine the level of clinically acceptable reduction in injected fluorine 18 (18F) fluorodeoxyglucose (FDG) dose in time-of-flight (TOF)-positron emission tomography(PET)/magnetic resonance (MR) imaging by using silicon photomultiplier (SiPM) detectors compared with TOF-PET/computed tomography (CT) using ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2017162305
更新日期:2018-01-01 00:00:00
abstract::The radiologic studies of 107 patients with pulsatile tinnitus or a vascular retrotympanic mass were retrospectively reviewed. Of the 100 patients with pulsatile tinnitus, 25 had objective tinnitus. A vascular tympanic membrane was present in 37 cases (35%). Normal vascular variants were present in 23 patients (21%). ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.174.2.2296650
更新日期:1990-02-01 00:00:00