Abstract:
:Necrobiotic xanthogranuloma (NXG) is an indolent non-Langerhans cell histiocytosis characterized by yellow xanthomatous plaques that tend to ulcerate. Necrobiotic xanthogranulomas have a predilection for the bilateral periorbital region and often present with consequential ophthalmic findings. Histopathology usually reveals a distinctive pattern of histiocytic xanthogranuloma with hyaline necrobiosis. Necrobiotic xanthogranuloma has been documented to have a close association with paraproteinemia. We report the case of a 76-year-old man with periorbital NXG without development of a monoclonal gammopathy. Clinically, the patient presented with dry eyes and substantial periorbital edema with multiple yellow indurated plaques. He developed the condition 30 years prior to presentation at which time it was initially diagnosed as xanthelasma. He underwent surgical excision of the lesions 10 years prior to the current presentation and biopsy results revealed a diagnosis of NXG. The periorbital lesions recurred several years prior to presentation, prompting annual computed tomography scans to rule out ocular invasion. Periorbital edema and plaques improved during a 6-month regimen of acitretin but returned to baseline just months after discontinuation.
journal_name
Cutisjournal_title
Cutisauthors
Seastrom S,Bookout A,Hogan DJsubject
Has Abstractpub_date
2014-12-01 00:00:00pages
293-6issue
6eissn
0011-4162issn
2326-6929journal_volume
94pub_type
杂志文章相关文献
CUTIS文献大全abstract::Since the introduction of the first commercial deodorant and antiperspirant, use of underarm products has assumed an increasing role in individual personal care habits. This paper reviews the physiology of human perspiration and describes the function and classification of antiperspirants and deodorants. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1987-06-01 00:00:00
abstract::Basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (SCCs) are the most common malignancies in humans. Together, they constitute approximately 95% of nonmelanoma skin cancers (NMSCs). Surgical excision remains the mainstay of therapy of low-risk NMSC, though Mohs micrographic surgery is the gold standa...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::A case of perianal condylomata lata, one of a variety of skin lesions manifested in secondary syphilis, is presented. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract::An otherwise asymptomatic woman presented with the recent onset of telangiectasias of the lips and fingertips, and without a family history of similar lesions. Results of laboratory tests included elevated liver function, positive antimitochondrial antibodies, and microscopic findings compatible with the diagnosis of ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1985-02-01 00:00:00
abstract::Intravascular lymphoma (IVL) is a non-Hodgkin lymphoma in which atypical lymphocytes accumulate within small blood vessels. Patients most commonly present with neurologic and cutaneous findings; however, any organ system may be affected, which leads to difficulties in diagnosis. The objectives of this article are to r...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2008-10-01 00:00:00
abstract::We report a case of pedal tuberoeruptive xanthomatosis associated with ethanol-induced type Vhyperlipoproteinemia that was controlled with diet, withdrawal from ethanol use, and the fibric acid derivative gemfibrozil. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::The value of in vivo reflectance confocal microscopy (RCM) as a noninvasive adjunctive tool in dermatology has steadily advanced since its inception. With RCM, dermatologists can view horizontal sections of lesions in a resolution comparable to histology, observe dynamic processes in living skin, and monitor lesion ev...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2015-05-01 00:00:00
abstract::Laser treatment of Ota nevi can be complicated, particularly in darker skin types, as there is a higher risk for adverse effects if the laser is not carefully employed. We report a case of successful treatment of an Ota nevus in a patient with Fitzpatrick skin type IV with the novel 532-nm solid-state picosecond laser...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2017-03-01 00:00:00
abstract::A 52-year-old Chinese man was found to have a benign thymoma and pemphigus erythematosus (PE). Initially, most of his skin lesions appeared on the scars of the surgical incisions and suture sites three months after he underwent thymectomy. To our knowledge, this is the first report documenting the skin lesions of PE o...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Psoriasis is a chronic, immune-mediated skin disease affecting approximately 1% to 3% of the human immunodeficiency virus (HIV)-infected population. Psoriasis appears in patients with HIV either as the first clinical manifestation of the disease or, less commonly, during the advanced stages of HIV when it has progress...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2008-09-01 00:00:00
abstract::Porokeratosis, a keratinization and fibroblast cutaneous disorder, is a progressive disease with limited treatment options. We describe a case of linear porokeratosis that responded favorably to a series of 585 nm pulsed dye laser treatments. In addition to its vascular specificity, the pulsed dye laser presumably pro...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract::Pseudoxanthoma elasticum (PXE) is a genetic disorder of connective tissue with multi-systemic manifestations. Although the skin changes are striking, the eye and cardiovascular lesions can be most devastating to the patient. A review of the clinical and pathologic findings and recent therapeutic approaches is presente...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1978-06-01 00:00:00
abstract::Confocal microscopy is an imaging tool that uses a laser system to image the skin noninvasively with cellular resolution. With both in vivo and ex vivo systems, tissue can be imaged rapidly without damaging the sample. Herein, we discuss the capabilities of the ex vivo confocal microscope and its implementation for tr...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2017-08-01 00:00:00
abstract::Presented herein is a review of the beneficial use of the folic acid antagonist, aminopterin, in the treatment of psoriasis and other dermatologic disorders. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1979-04-01 00:00:00
abstract::Vitiligo vulgaris is an autoimmune pigmentary disorder with no universally efficacious therapeutic options. Separate applications of calcipotriene ointment 0.005% and topical corticosteroid ointments have been successful in the repigmentation of vitiligo. We sought to examine the efficacy of a combination calcipotrien...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::A patient with primary cutaneous B cell lymphoma that presented as a solitary nodule on the abdomen was successfully treated with local radiotherapy. A brief review of special studies used to diagnose this tumor as well as clinical characteristics of the tumor is presented. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::An aqueous gel formulation containing solubilized clindamycin phosphate 1.2% and a stable combination of both solubilized and crystalline tretinoin 0.025% (clin/tret) has been evaluated in 3 pivotal phase 3 studies, among other studies including a 52-week trial. The pivotal studies enrolled 4550 participants 12 years ...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2008-05-01 00:00:00
abstract::An odontogenic cutaneous sinus tract (OCST) of dental origin is an uncommon and frequently misdiagnosed lesion that is caused by chronic periodontitis. Given that OCSTs often lack symptoms, are located on the lower face, and can have notable variations in clinical appearance, they can be mistaken for more common derma...
journal_title:Cutis
pub_type: 杂志文章
doi:10.12788/cutis.0081
更新日期:2020-10-01 00:00:00
abstract::We assess the safety and efficacy of imiquimod cream 3.75% and 2.5% in men with external genital warts (EGWs). Two multicenter, randomized, double-blind, placebo-controlled studies were conducted in a total of 447 (225 from study 1 and 222 from study 2) male patients (aged ≥12 years) with 2 to 30 EGWs and a total wart...
journal_title:Cutis
pub_type: 杂志文章,多中心研究,随机对照试验
doi:
更新日期:2015-10-01 00:00:00
abstract::A solution of clindamycin in 50 percent alcohol used topically in the treatment of acne was found to be an adequate therapy to replace systemic tetracycline. Patients followed over a two to three month period showed improvement in lesion counts and subjective improvement as evaluated by the investigator and patient. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract::Erythromelanosis follicularis faciei et colli (EFFC) is a rare disorder of unknown etiology characterized by the clinical triad of well-demarcated erythema, hyperpigmentation, and follicular plugging on the face. For many years, it was thought to be a disease occurring in males with ethnical cutaneous pigmentation. Th...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2007-06-01 00:00:00
abstract::Vandetanib is a once-daily oral multikinase inhibitor that targets the rearranged during transfection (RET) tyrosine kinase, vascular endothelial growth factor receptor, and epidermal growth factor receptor. Among its observed toxicity profile is QT prolongation, diarrhea, and rash, including photosensitivity. This ar...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2019-05-01 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly becoming a major source of systemic infection in the community and healthcare settings. The disease is responsible for deaths among individuals without known risk factors and presents a therapeutic challenge for clinicians because of the bacteria's com...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2008-04-01 00:00:00
abstract::We have reviewed a wide spectrum of disorders producing a swollen limb, some common, others uncommon. Cutaneous signs are often seen in association with these conditions and careful attention to them by the dermatologist may be helpful in determining an accurate diagnosis and appropriate therapy. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::A 69-year-old black woman with a patchy chronic eczematous dermatitis developed striking blue macules within her lesions. These discolored macules contained an abnormal dermal mononuclear cell infiltrate typical of mycosis fungoides. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1984-04-01 00:00:00
abstract::Elephantiasis nostras is one of the most striking yet, at the same time, one of the most poorly understood dermatologic entities. We present a report on two patients with this disorder, each of whom had a marked enlargement of a lower extremity following recurrent attacks of infection and/or ulceration. In one case ob...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Multiple systemic manifestations of renal cell carcinoma have been reported. The first case of a discoid lupus erythematosus-like syndrome and the third reported case of hypercalcemia associated with an elevated serum prostaglandin E2 level in a patient with renal cell carcinoma is presented herein. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::Soft tissue lesions are among the most commonly occurring pathologic conditions in the oral cavity. The causes of these lesions can vary from immunologic and viral reactions to underlying systemic disease, dermatologic lesions, or neoplasms. The diagnosis of these conditions is usually based on the history, clinical a...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::There currently are 3 topical agents approved by the US Food and Drug Administration (FDA) to treat onychomycosis: tavaborole, efinaconazole, and ciclopirox. The phase 3 clinical trial designs for these treatments and their notable differences make it difficult for clinicians to interpret the data into clinical practi...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2017-10-01 00:00:00
abstract::Dermacentor ticks are hard ticks found throughout most of North America and are easily identified by their large size, ornate scutum, and prominent dorsal pits. They are important disease vectors and are implicated in transmission of Rocky Mountain spotted fever (RMSF), Colorado tick fever, tularemia, and erlichiosis....
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2018-01-01 00:00:00