Abstract:
:Two patients with an acute organic brain syndrome and accompanying neurological symptoms are described. Extensive work up showed that both patients suffered from small-cell lung cancer. Cerebral metastases were absent. Following chemotherapy and radiotherapy to the primary tumor one of the two patients showed a complete remission of psychiatric symptoms for one year. A paraneoplastic origin of this syndrome, in the literature known as limbic encephalitis, is postulated. The exact cause of this syndrome is yet unknown. Recent research reveals data indicating an immunological pathogenesis. The major clinical importance of this (neuro)-psychiatric syndrome is that its appearance may serve as a warning sign for an occult malignancy; furthermore, effective treatment of the primary malignancy can reverse the encephalitis. Thus antitumor therapy can result in a prolonged survival and considerably improved quality of life.
journal_name
Gen Hosp Psychiatryjournal_title
General hospital psychiatryauthors
den Hollander AM,van Hulst AM,Meerwaldt JD,Haasjes JGdoi
10.1016/0163-8343(89)90132-1subject
Has Abstractpub_date
1989-11-01 00:00:00pages
388-92issue
6eissn
0163-8343issn
1873-7714pii
0163-8343(89)90132-1journal_volume
11pub_type
杂志文章abstract:OBJECTIVE:To assess the following among women hospitalized antenatally due to high-risk pregnancies: (1) rates of depression symptoms and anxiety symptoms, (2) changes in depression symptoms and anxiety symptoms and, (3) rates of mental health treatment. METHODS:Sixty-two participants hospitalized for high-risk obstet...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.07.011
更新日期:2014-11-01 00:00:00
abstract::Pernicious anemia has been associated with various psychiatric manifestations, such as depression, mania and psychosis. Psychiatric symptoms can sometimes occur without hematological and neurological abnormalities and can be prodromal of vitamin B12 deficiency. We report a case of autoimmune B12 deficiency presenting ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2015.02.003
更新日期:2015-05-01 00:00:00
abstract::The authors explore the difficulties present in the capacity evaluation of patients with strong religious beliefs. The article reviews the legal protection for treatment refusal on religious grounds as well as psychiatry's approach to religion. Clinical cases encountered in an urban hospital are presented to highlight...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(96)00003-5
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:Primary care providers are increasingly taking on the role of ad hoc mental health provider. However, before patients in primary care can be treated, they must be identified. This study set out to validate a very brief screening instrument for identifying primary care patients with anxiety and depression. ME...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2005.08.010
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:Every year, millions of Americans become informal caregivers to loved ones admitted to Neuroscience Intensive Care Units (Neuro-ICU), and face challenges to Quality of Life (QoL). This study sought to identify associations between resiliency, distress, and caregiver QoL at time of Neuro-ICU admission. METHOD...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2018.02.012
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:Hospital crowding is a public health problem that may impact on the quality of medical treatment and increase the risk of developing traumatic stress, e.g., after myocardial infarction (MI). This study examines whether subjective appraisal of crowding at hospital admission due to MI is associated with acute s...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2015.11.004
更新日期:2016-03-01 00:00:00
abstract::This paper presents a checklist of conceptual issues and operational guidelines determining the organization of clinical services within a general hospital department of psychiatry. Issues emphasized include philosophy, target population, definition, structure, location, financing, and cost effectiveness of services, ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(81)90039-6
更新日期:1981-12-01 00:00:00
abstract:BACKGROUND:Many patients treated in the emergency department (ED) for non-psychiatric complaints have elevated suicide risk. Universal screening can detect occult suicide risk, but gold standard risk measurement tools, such as the Beck Scale for Suicidal Ideation (BSS), are too long and cumbersome for ED use. OBJECTIV...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2018.08.004
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:History of prolonged traumatization has been associated with reduced quality of life (QoL) and difficulties in coping with major life-threatening conditions. We assessed the association between the impact of Holocaust experience (posttraumatic symptoms) and QoL of patients before and after an open heart surge...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2004.06.005
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:Psychogenic factors may play a contributory role in the development or persistence of lichen simplex chronicus (LSC). The objective of this study was to evaluate the psychiatric profile of patients with LSC including depression and dissociative experiences. METHOD:Dermatology outpatients with a LSC (n=30) we...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2007.01.006
更新日期:2007-05-01 00:00:00
abstract::The diagnosis of psychopathology among geriatric acute inpatients requires comprehensive evaluation. To our knowledge, no recently published papers in the geriatric psychiatry literature have systematically examined diagnostic changes during single admissions. We reviewed the charts of 159 patients consecutively admit...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(00)00118-3
更新日期:2001-01-01 00:00:00
abstract::Several predictors of the course of depression and generalized anxiety have been identified. Whether these predictors provide a solid basis for primary care physicians (PCPs) to give an accurate prognosis remains unclear. A parallel study showed modest agreement between PCP prognosis and observed course (kappa< or = 0...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(02)00183-4
更新日期:2002-05-01 00:00:00
abstract::As the consultation-liaison psychiatrist for a large burn service, the author investigated the undermedication for pain. This phenomenon could not be adequately explained by the staff's insensitivity, by mistaken ideas about analgesics, or by fears of iatrogenic addiction. For both patients and staff, the pain served ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(84)90026-4
更新日期:1984-10-01 00:00:00
abstract::The treatment of adolescents in a general hospital setting is fraught with difficulty. There are significant limitations to time, space, finances, and the physical plant. There are limitations to the numbers, types, mix of patients with other patients, and the types of treatment available. To deal with these issues, a...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(88)90097-7
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVE:To determine whether a smartphone application (app) with an electronic headache diary and a progressive muscle relaxation (PMR) intervention is feasible and acceptable to people presenting to the Emergency Department (ED) with migraine. METHODS:This single arm prospective study assessed feasibility by actual...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2020.12.009
更新日期:2021-01-08 00:00:00
abstract:OBJECTIVE:To characterize the US national level healthcare utilization patterns of patients with commercial insurance plans before and after a psychiatric hospitalization admitted through the emergency department (ED) using insurance claims data. METHOD:We identified 34,250 patients from multiple commercial health ins...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2020.10.001
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To report a case of Alzheimer's disease (AD) following mild traumatic brain injury (TBI). METHOD:Case report. RESULTS:We report the time course of AD following mild TBI with evidence of AD pathology. A patient complained of minor memory disturbance 6 months after TBI and was diagnosed with mild cognitive im...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.09.016
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The majority of VA patient suicides are completed with firearms. Interventions that delay patients' gun access during high-risk periods may reduce suicide, but may not be acceptable to VA stakeholders or may be challenging to implement. Using qualitative methods, stakeholders' perceptions about gun safety an...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2012.07.012
更新日期:2012-11-01 00:00:00
abstract::Post-stroke depression is a potentially persistent complication of stroke. Electroconvulsive therapy (ECT) is an effective treatment for depression, but with limited data regarding safety in stroke patients. We report the case of a 30-year-old woman with a history of stroke and antiphospholipid syndrome, who became de...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.08.006
更新日期:2012-01-01 00:00:00
abstract::Bromocriptine, an ergot alkaloid dopamine agonist, is a recent common treatment for suppression of lactation in postpartum women. A case is presented of a postpartum woman prescribed bromocriptine for suppression of lactation who developed hypertension, headaches, blurry vision, seizures, and pituitary hemorrhage. Dif...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(91)90131-f
更新日期:1991-07-01 00:00:00
abstract::Ziconotide is used intrathecally in the management of severe chronic pain that contains a warning against neuropsychiatric adverse events. The definition of psychiatric events is broad and management strategies are vague. This case report describes a 49-year-old female who was admitted to the acute psychiatric unit to...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.10.001
更新日期:2015-01-01 00:00:00
abstract::We report on the case of a patient with acquired immune deficiency syndrome- and Cryptococcus neoformans meningitis-related mania in which olanzapine was successfully used adjunctively and transiently to antifungal therapy. ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.11.004
更新日期:2011-05-01 00:00:00
abstract::Family systems theory provides the physician with a comprehensive paradigm to investigate the social and interpersonal context of physical illness. All physical illnesses, particularly life-threatening and chronic ones, profoundly affect the family life of the patient, and the changed family circumstances in turn have...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/0163-8343(90)90003-u
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:The goal of this analysis was to examine the effect of benzodiazepine use during pregnancy on maternal and neonatal outcomes in a cohort of women with psychiatric disorders. METHODS:794 evaluable women from the Massachusetts General Hospital National Pregnancy Registry for Psychiatric Medications were follow...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2018.05.010
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Delusional disorder is an uncommon psychotic disorder. The first-line treatments for this chronic and resistant condition are antipsychotic medications, usually associated with several side effects that can exacerbate poor adherence. Conversely, aripiprazole is a well-tolerated antipsychotic drug that is eff...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.genhosppsych.2020.06.012
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:This prospective study investigates the relationships between depressive symptoms, psychiatric medication use, and their interaction on risk of developing type 2 diabetes. METHOD:Data come from the 1998-2010 waves of the Health and Retirement Study, a US nationally representative cohort of adults aged 51 yea...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2015.05.008
更新日期:2015-09-01 00:00:00
abstract::This report describes the background, rationale, and research plan for a comparative treatment trial of the effectiveness of paroxetine, problem-solving therapy (PST-PC), and placebo in the treatment of minor depression and dysthymia in primary care patients. Patients were recruited from a variety of primary care prac...
journal_title:General hospital psychiatry
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1016/s0163-8343(99)00023-7
更新日期:1999-07-01 00:00:00
abstract::This study surveys Khmer refugees attending two psychiatric clinics to determine both the prevalence of panic disorder as well as panic attack subtypes in those suffering panic disorder. A culturally valid adaptation of the SCID-panic module, the Cambodian Panic Disorder Survey (CPDS), was administered to 89 consecuti...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(00)00102-x
更新日期:2000-11-01 00:00:00
abstract::In the Netherlands, the prescription of beta-blockers to patients older than 70 years has increased sharply in recent years. The neuropsychiatric adverse reactions associated with the use of beta-blockers are relatively uncommon and they are mostly seen with poisoning or overdose. We describe an 81-year-old man who de...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.04.008
更新日期:2010-11-01 00:00:00
abstract::The following case presents a 22-year-old woman with relapsing polychondritis and depression treated in liaison, consultation, and outpatient settings by one psychiatrist using a variety of techniques. The discussion focuses on the implications of the case for integrated medical model and psychotherapeutic care, and f...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(83)90010-5
更新日期:1983-12-01 00:00:00