Endometrial adenocarcinoma: clinical outcome in 881 patients and analysis of 146 patients whose deaths were due to endometrial cancer.

abstract：OBJECTIVE:The aims of this study were (1) to examine whether HPV DNA is persistently detected in the cervix after therapeutic conization for CIN 3 and (2) to explore whether a patient with persistence of HPV infection is at risk of developing recurrent disease. METHODS:Of 74 patients referred with CIN 3, 58 who were t...

journal_title：Gynecologic oncology

authors： Nagai Y,Maehama T,Asato T,Kanazawa K

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To examine the effect of postsurgical surveillance on survival of patients with FIGO stage I/II endometrial adenocarcinoma. METHODS:We examined the records of 354 patients who underwent primary surgical therapy for FIGO stage I/II endometrial adenocarcinoma. In patients who developed recurrent disease, we de...

journal_title：Gynecologic oncology

authors： Berchuck A,Anspach C,Evans AC,Soper JT,Rodriguez GC,Dodge R,Robboy S,Clarke-Pearson DL

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Obesity confers an overall increased risk for development of endometrial cancer. However there are conflicting reports regarding the effect of obesity on patients' overall and disease specific survival. The purpose of this study was to evaluate the effect of obesity on survival in women with endometrial canc...

journal_title：Gynecologic oncology

authors： Van Arsdale A,Miller DT,Kuo DY,Isani S,Sanchez L,Nevadunsky NS

更新日期：2019-07-01 00:00:00

abstract：:The CA 125 radioimmunoassay has been increasingly used to monitor the course of patients with ovarian epithelial carcinomas. The purpose of this report is to describe our experience in the use of this assay and to better define its clinical utility. Fifty-one patients had serum CA 125 follow-up during primary chemothe...

journal_title：Gynecologic oncology

authors： Podczaski E,Whitney C,Manetta A,Larson JE,Kirk J,Stevens CW,Lyter J,Mortel R

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVES:Six cycles of consolidation chemotherapy have become the standard for ovarian cancer treatment regimen following primary cytoreduction, yet with neoadjuvant chemotherapy (NAC), only 3 consolidation cycles are used. This study examines the effects of number of chemotherapy cycles in women with ovarian cancer ...

journal_title：Gynecologic oncology

authors： Altman AD,McGee J,May T,Lane K,Lu L,Xu W,Ghatage P,Rosen B

更新日期：2017-11-01 00:00:00

abstract：:Between 1978 and 1983, one hundred and forty-six patients with CIN I-III were treated with the carbon dioxide laser and 129 have been followed for 6 to 58 months. The remission rate was 92.2% after one treatment and 98.4% after two treatments. All persistent lesions were detected within 8 weeks after treatment. After ...

journal_title：Gynecologic oncology

authors： Tsukamoto N

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to evaluate the impact of the 1999 national recommendations for ovarian cancer surgery in England to be performed by specialist surgeons in specialist centres. METHODS:A retrospective analysis of English cancer registry records, Hospital Episode Statistics (HES) data for all English ...

journal_title：Gynecologic oncology

authors： Butler J,Gildea C,Poole J,Meechan D,Nordin A

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Our objective is to examine how selenium (Se) supplementation influences oxidative stress (malondialdehyde) and the glutathione peroxidase system in patients with ovarian cancer undergoing chemotherapy. MATERIAL:The study group included 31 patients with ovarian cancer undergoing chemotherapy receiving the dr...

journal_title：Gynecologic oncology

authors： Sieja K,Talerczyk M

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To conduct a systematic review of the literature regarding the systemic treatment of advanced uterine sarcoma and provide an evidence-based summary of the available literature. METHODS:MEDLINE, EMBASE, and the Cochrane Library databases were searched. "Uterine sarcoma," "leiomyosarcoma," "mixed mesodermal tu...

journal_title：Gynecologic oncology

authors： Kanjeekal S,Chambers A,Fung MF,Verma S

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:The placental site trophoblastic tumor is a rare form of gestational trophoblastic disease. Fifteen percent of reported cases have been fatal, but predicting behavior in individual patients has been challenging. METHODS:The clinical, gross and histopathological features of 55 cases and 180 cases in the liter...

journal_title：Gynecologic oncology

authors： Baergen RN,Rutgers JL,Young RH,Osann K,Scully RE

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:The present study was planned to measure preoperative levels of soluble urokinase plasminogen activator receptor (suPAR) in plasma from patients with gynecological diseases, and to test for a relationship to clinical and biochemical patient characteristics. METHODS:Using a specific and sensitive kinetic ELIS...

journal_title：Gynecologic oncology

authors： Riisbro R,Stephens RW,Brünner N,Christensen IJ,Nielsen HJ,Heilmann L,von Tempelhoff GF

更新日期：2001-09-01 00:00:00

abstract：:Nucleolar Organizer Regions (NORs) code for ribosomal RNA and are thought to be an accurate representation of the percentage of cells in S-phase. NORs are associated with nonhistone nucleoproteins, which can be stained with silver (AgNORs). An increased number of AgNORs has been observed in many malignancies. AgNORs w...

journal_title：Gynecologic oncology

authors： Chalas E,Chumas J,Barbieri R,Mann WJ

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term outcomes of young early stage cervical cancer patients wishing to preserve their childbearing potential. METHODS:Data of young (aged <40 years) patients with early stage cervical cancer were prospectively collected. All patients with stage IA2, IB1 and IB2 cervical cancer were inclu...

journal_title：Gynecologic oncology

authors： Bogani G,Chiappa V,Vinti D,Somigliana E,Filippi F,Murru G,Murgia F,Martinelli F,Ditto A,Raspagliesi F

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Our aim was to evaluate the feasibility of a novel technique using single-port laparoscopy for the complete surgical staging of endometrial cancer. METHODS:Total hysterectomy, bilateral salpingo-oophorectomy, pelvic lymphadenectomy and para-aortic lymphadenectomy was performed using a single-port device in t...

journal_title：Gynecologic oncology

authors： Zapardiel I,Moreno E,Piñera A,De Santiago J

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:To compare outcomes of patients undergoing continent or incontinent urinary diversion after pelvic exenteration for gynecologic malignancies. METHODS:Data on patients who underwent pelvic exenteration for gynecologic malignancies at The University of Texas MD Anderson Cancer Center between January 1993 and D...

journal_title：Gynecologic oncology

authors： Urh A,Soliman PT,Schmeler KM,Westin S,Frumovitz M,Nick AM,Fellman B,Urbauer DL,Ramirez PT

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Receptors for estrogen (ER), progesterone (PR), or androgen (AR) are predictive and prognostic markers of malignancy of multiple endocrine organs, including endometrial and breast cancer. However, the role of ERs, PRs, or ARs in the carcinogenesis of ovarian cancer, another sex hormone-dependent malignancy, i...

journal_title：Gynecologic oncology

authors： Lee P,Rosen DG,Zhu C,Silva EG,Liu J

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:While there is ample literature on prognostic factors for uterine cancer, currently there are nomeans to estimate an individual's risk for recurrence or to differentiate the risk of loco-regional recurrence from distant recurrence. We addressed this gap by developing nomograms to individualize the risk of rec...

journal_title：Gynecologic oncology

authors： Kondalsamy-Chennakesavan S,Yu C,Kattan MW,Leung Y,Sykes P,Nascimento M,Nicklin J,Perrin L,Crandon A,Chetty N,Land R,Garrett A,Obermair A

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the incidence of thrombocytosis in epithelial ovarian carcinoma and examine associations with clinico-pathologic features. Thrombocytosis (platelet counts >400 x 10(9)/l) has been identified as a poor prognostic factor in many cancers. Platelet-secreted factors may...

journal_title：Gynecologic oncology

authors： Li AJ,Madden AC,Cass I,Leuchter RS,Lagasse LD,Karlan BY

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:To analyze the sites of relapse and overall survival in women with neuroendocrine marker-positive small cell carcinoma of the cervix. METHODS:The records of all women who had their initial treatment for cervical cancer at The University of Texas M.D. Anderson Cancer Center between 1980 and 2000 were reviewe...

journal_title：Gynecologic oncology

authors： Viswanathan AN,Deavers MT,Jhingran A,Ramirez PT,Levenback C,Eifel PJ

更新日期：2004-04-01 00:00:00

abstract：:Immunohistochemical studies were performed to investigate the prognostic significance of p53 protein expression in 46 patients with stage IIIB squamous cell carcinoma of the uterine cervix who were treated with radiation therapy alone. Tumor cells showed p53 protein expression in 29 of 46 patients. The 5-year overall ...

journal_title：Gynecologic oncology

authors： Ebara T,Mitsuhashi N,Saito Y,Sakurai H,Hasegawa M,Takahashi M,Takahashi T,Hayakawa K,Niibe H

更新日期：1996-11-01 00:00:00

abstract：:Endocrine and clinicopathologic findings in a 77-year-old woman with ovarian mucinous adenofibroma of borderline malignancy are reported. The preoperative levels of testosterone, androstenedione, estrone, and estradiol in her peripheral blood were 91 ng/ml, 3.78 ng/ml, 82 pg/ml, and 35 pg/ml, respectively, abnormally ...

journal_title：Gynecologic oncology

authors： Tohya T,Mizutani H,Katabuchi H,Miyazaki K,Okamura H

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:We report a case of uterine leiomyosarcoma occurring after uterine artery embolization and review the previously published cases. We estimate the incidence of sarcoma after UAE, the mean diagnostic delay in young women undergoing this procedure and review the potential and limits of preoperative procedures in...

journal_title：Gynecologic oncology

authors： Papadia A,Salom EM,Fulcheri E,Ragni N

更新日期：2007-01-01 00:00:00

abstract：:Between August 1990 and January 1992, 184 patients with squamous cell carcinoma of the cervix, FIGO stage IIB-IVA, were randomized to receive either two cycles of bleomycin, ifosfamide-mesna, and cis-platinum (BIP) chemotherapy (CT) followed by radiotherapy (RT) ("CT-RT group," n = 94) or RT alone (RT group, n = 90). ...

journal_title：Gynecologic oncology

authors： Kumar L,Kaushal R,Nandy M,Biswal BM,Kumar S,Kriplani A,Singh R,Rath GK,Kochupillai V

更新日期：1994-09-01 00:00:00

abstract：:To identify FIGO I ovarian cancer patients at high risk, prognostic values of quantitative pathological features (volume percentage of epithelium, mitotic activity index, mean (MNA) and standard deviation of nuclear profile area, and volume-weighted mean nuclear volume (MNV) have been investigated in comparison with c...

journal_title：Gynecologic oncology

authors： Brugghe J,Baak JP,Wiltshaw E,Brinkhuis M,Meijer GA,Fisher C

更新日期：1998-01-01 00:00:00

abstract：:Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely aggressive malignancy associated with a poor overall prognosis. Women affected may vary in age, but are most often diagnosed in their perimenopausal years. Presenting symptoms may be vague and mimic other benign uterine conditions. P...

journal_title：Gynecologic oncology

authors： Roberts ME,Aynardi JT,Chu CS

更新日期：2018-12-01 00:00:00

abstract：:Twenty-three evaluable patients with refractory epithelial ovarian cancer were treated with bisantrene (CL216,942). The drug was given as a single-dose injection every 3 weeks. One patient (4%) showed a partial response. The compound thus has limited activity against this malignancy. ...

journal_title：Gynecologic oncology

authors： Kavanagh JJ,Gershenson DM,Saul PB,Copeland LJ

更新日期：1986-01-01 00:00:00

abstract：:Eight patients with cervical intraepithelial neoplasia (CIN) were administered perilesional injections of human recombinant interferon gamma (IFN-gamma), and the response was evaluated by colposcopy and exfoliative cytology and then by histopathology. In all patients, colposcopic and cytologic findings improved after ...

journal_title：Gynecologic oncology

authors： Iwasaka T,Hayashi Y,Yokoyama M,Hachisuga T,Sugimori H

更新日期：1990-04-01 00:00:00

abstract：:Thirty patients with uterine papillary serous carcinoma were treated with intravenous cisplatin, doxorubicin, and cyclophosphamide (CAP) chemotherapy, a combination with proven efficacy against ovarian carcinoma. Nineteen patients were given CAP as an adjuvant soon after surgery. Eleven patients were treated after rec...

journal_title：Gynecologic oncology

authors： Price FV,Chambers SK,Carcangiu ML,Kohorn EI,Schwartz PE,Chambers JT

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the survival impact of residual disease at the time of primary surgery for patients with Stage III and IV endometrial carcinoma; to assess morbidity associated with surgical cytoreduction. METHOD:All patients with endometrial carcinoma who underwent primary surgical therapy at the University of M...

journal_title：Gynecologic oncology

authors： Lambrou NC,Gómez-Marín O,Mirhashemi R,Beach H,Salom E,Almeida-Parra Z,Peñalver M

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:In advanced ovarian cancer, patients cytoreduced to no visible disease appear to have improved survival compared to patients with visible residual tumor < or = 10 mm. It remains unresolved whether this is due to better chemotherapy response and/or simply "re-setting the clock," such that patients with less re...

journal_title：Gynecologic oncology

authors： Eisenhauer EL,Abu-Rustum NR,Sonoda Y,Aghajanian C,Barakat RR,Chi DS

更新日期：2008-02-01 00:00:00