Abstract:
:The progressive increase in the prevalence of obesity and aging in the population is resulting in increased healthcare and disability spending. The burden of obesity is particularly relevant in old age, due to accumulating co-morbidities and changes in body composition. Sarcopenic obesity, a mix of over- and under-nutrition, causes frailty, disability, and problems in social and psychological areas, impacting overall health-related quality of life (HR-QOL). The relationship between obesity, aging, and HR-QOL is, however, much more complex than generally acknowledged and is difficult to disentangle. The impact of obesity on HR-QOL is particularly strong in young people, who are free of co-morbidities. It progressively attenuates, compared with the general population, with advancing age, when co-morbid conditions are diffusely present and reduce the perceived health status, independent of obesity. However, even this apparent 'obesity paradox' should not minimize the importance of obesity on HR-QOL, as other obesity-associated limitations and disabilities do impact HR-QOL in older age. A patient-centered approach aimed at reducing the disability and social isolation of advancing age is mandatory to improve HR-QOL in any class of obesity.
journal_name
Pharmacoeconomicsjournal_title
PharmacoEconomicsauthors
Corica F,Bianchi G,Corsonello A,Mazzella N,Lattanzio F,Marchesini Gdoi
10.1007/s40273-014-0237-8subject
Has Abstractpub_date
2015-07-01 00:00:00pages
655-72issue
7eissn
1170-7690issn
1179-2027journal_volume
33pub_type
杂志文章,评审abstract:BACKGROUND:Schizophrenia is a devastating and costly illness that affects 1% of the population in the US. Effective pharmacological therapies are available but suboptimal patient adherence to either acute or long-term therapeutic regimens reduces their effectiveness. The availability of a long-acting injection (LAI) fo...
journal_title:PharmacoEconomics
pub_type: 杂志文章
doi:10.2165/00019053-200523030-00009
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journal_title:PharmacoEconomics
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:PharmacoEconomics
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journal_title:PharmacoEconomics
pub_type: 杂志文章
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journal_title:PharmacoEconomics
pub_type: 杂志文章
doi:10.2165/00019053-199610050-00006
更新日期:1996-11-01 00:00:00
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journal_title:PharmacoEconomics
pub_type: 杂志文章,评审
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更新日期:1995-01-01 00:00:00
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journal_title:PharmacoEconomics
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journal_title:PharmacoEconomics
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更新日期:1996-01-01 00:00:00
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更新日期:2009-01-01 00:00:00
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journal_title:PharmacoEconomics
pub_type: 临床试验,杂志文章,多中心研究
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journal_title:PharmacoEconomics
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更新日期:1998-09-01 00:00:00
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journal_title:PharmacoEconomics
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journal_title:PharmacoEconomics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2020-11-01 00:00:00
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journal_title:PharmacoEconomics
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更新日期:2008-01-01 00:00:00
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journal_title:PharmacoEconomics
pub_type: 杂志文章
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更新日期:2004-01-01 00:00:00
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更新日期:1998-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2004-01-01 00:00:00