Changes in the diffusion capacity for carbon monoxide and the development of non-infectious pneumonitis in patients with metastatic renal cell carcinoma treated with everolimus.

abstract：:Polymerase chain reaction and single strand conformation polymorphism (PCR-SSCP) analysis of the p53 tumor suppressor gene (from exon 2 to 9) was performed on samples from 47 adult patients with primary myelodysplastic syndrome (MDS). Point mutation was found in 5 (11%) patients: exon 7 in 3, exon 4 in 1 and intron 5 ...

journal_title：Anticancer research

authors： Tang JL,Tien HF,Lin MT,Chen PJ,Chen YC

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:A gastrostomy feeding tube is one method for long-term feeding support in patients undergoing radio(chemo)therapy for head and neck cancer (HNC). The aim of this study was to analyze the safety of prophylactic gastrostomy tube placement and usage in HNSCC patients. PATIENTS AND METHODS:HNC patients undergoi...

journal_title：Anticancer research

authors： Sieron HL,Eberle F,Gress TM,Mahnken AH,Wiegand S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND/AIM:Although the advent of Helicobacter pylori eradication and global societal changes are widely assumed to impact on gastric cancer (GC)-related mortality, there is remarkable little quantitative and qualitative insight into the nature of its effects. Here, we exploited a nationwide reporting system to inv...

journal_title：Anticancer research

authors： Yin J,Song JN,Bai ZG,Cai J,Zhang J,Zheng Z,Wu HW,Ye PP,Gao X,Zhang ZT

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The long-term goal of this work is to develop a new therapeutic regimen for the treatment of colon cancer in humans which will include hyperthermic intraperitoneal perfusion of verapamil as an alternative to administration of chemotherapy. METHODS AND RESULTS:Hyperthermia and verapamil caused a significant ...

journal_title：Anticancer research

authors： Shchepotin IB,McRae DA,Shabahang M,Buras RR,Evans SR

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Microparticles are known to be increased in various malignancies. In this prospective study, microparticle levels were evaluated in patients with benign and malignant ovarian lesions. PATIENTS AND METHODS:Microparticles from platelets/megakaryocytes, activated platelets and endothelial cells, tissue factor ...

journal_title：Anticancer research

authors： Rank A,Liebhardt S,Zwirner J,Burges A,Nieuwland R,Toth B

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Overexpression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 has recently been suggested to be a promising marker for early detection of lung cancer. The aim of this study was to determine the utility of its detection in bronchoscopic specimens. PATIENTS AND METHODS:Brushing and biopsy specimens ...

journal_title：Anticancer research

authors： Katsimpoula S,Patrinou-Georgoula M,Makrilia N,Dimakou K,Guialis A,Orfanidou D,Syrigos KN

更新日期：2009-04-01 00:00:00

abstract：:Cytochrome P450 CYP2D6 polymorphism is an autosomal recessive trait leading to impaired sparteine/ debrisoquine metabolism in 5-10% of the Caucasian population. Previous studies have associated affected individuals (poor metabolizers = PM) with susceptibility to bladder cancer and various forms of leukemia. In many ot...

journal_title：Anticancer research

authors： Wundrack I,Sasiadek M,Blin N

更新日期：1997-11-01 00:00:00

abstract：:Cytotoxicity of L-canavanive, a structural analogue of L-arginine, was tested by means of (1) inhibition of DNA synthesis in Balb/c-3T3 cell line and (2) inhibition of mitosis in peripheral blood lymphocytes in culture. The cytostatic nature of inhibition caused by L-canavanine was indicated by the complete recovery o...

journal_title：Anticancer research

authors： Naha PM

更新日期：1981-01-01 00:00:00

abstract：:The aim of the study was the evaluation of the detectability of treated liver metastases using one FDG-PET measurement. The study includes 42 patients (80 lesions) from different primary tumours. Standardized Uptake Values (SUV) as well as the tumour to liver Ratio (T/L) were used for evaluation. A T/L > 1.0 was consi...

journal_title：Anticancer research

authors： Mantaka P,Strauss AD,Strauss LG,Moehler M,Goldschmidt H,Oberdorfer F,Kontaxakis G,Van Kaick G

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Recombinant human interleukin-2 (IL-2) has a well-documented anti-tumor activity against RCC and has demonstrated a synergistic anti-tumor activity between doxorubicin and IL-2, thus providing better survival. This study investigated the toxicity and efficacy of the association between doxorubicin and IL-2, ...

journal_title：Anticancer research

authors： Naglieri E,Gebbia V,Durini E,Lelli G,Abbate I,Selvaggi FP,Di Tonno P,Colucci G

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND/AIM:Hepatic venous isolation and extracorporeal charcoal hemoperfusion (HVI-CHP) can reduce systemic exposure to hepatic arterial infusion (HAI) chemotherapy. The pre-existing HVI-CHP system has limited effectiveness against high-dose cisplatin; therefore, we designed a new system and evaluated its efficacy ...

journal_title：Anticancer research

authors： So S,Komatsu S,Takebe A,Kido M,Tanaka M,Toyama H,Ueno K,Fukumoto T

更新日期：2018-11-01 00:00:00

abstract：:We investigated the anti-metastatic effect of PKC412, a selective inhibitor of protein kinase C (PKC), on a spontaneous metastatic mouse model, which was prepared by inoculation with B16-BL6 mouse melanoma cells into the footpad of the right hind leg. At two weeks after inoculation, the primary tumor was amputated com...

journal_title：Anticancer research

authors： Nakamura K,Yoshikawa N,Yamaguchi Y,Kagota S,Shinozuka K,Kunitomo M

更新日期：2003-03-01 00:00:00

abstract：:The NB rat prostate adenocarcinoma model is one in which microscopic carcinoma can be induced via the use of testosterone and estrogen silastic implants. There is an incidence of large, grossly-positive tumors; which approaches 10% to 15%. Seventy-three percent of the animals subjected to this induction method for per...

journal_title：Anticancer research

authors： Drago JR

更新日期：1984-07-01 00:00:00

abstract：:We report a case of renal cell carcinoma with solitary metachronous metastasis to contralateral adrenal gland occurring 9 months after radical nephrectomy. The patient was treated with a contralateral adrenalectomy and is alive for 87 months. The literature was reviewed and 5-year survival of solitary metachronous met...

journal_title：Anticancer research

authors： Yamasaki Y,Koga S,Nishikido M,Noguchi M,Kanetake H,Saito Y

更新日期：1999-11-01 00:00:00

abstract：AIM:To determine the effectiveness of postoperative concurrent daily low-dose cisplatin-based chemoradiation (CCRT) in patients with high-risk cervical cancer. PATIENTS AND METHODS:Patients with stage IB, IIA, or IIB cervical cancer who were initially treated with radical hysterectomy and pelvic lymphadenectomy, and w...

journal_title：Anticancer research

authors： Mitsuhashi A,Uno T,Usui H,Tate S,Hirashiki K,Kato K,Kiyohara H,Kato S,Ito H,Shozu M

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND/AIM:Omega 3 polyunsaturated fatty acids (PUFAs) have been shown to inhibit the induction and progression of many tumor types. The aim of this study was to determine the anticancer effect of docosahexaenoic acid monoglyceride (MAG-DHA) alone and in combination with the chemotherapeutic agent carboplatin (CBT)...

journal_title：Anticancer research

authors： Morin C,Fortin S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells (MSCs) have attracted great interest in cancer therapy since the discovery of their tumor tropism. This study was performed to investigate the effects of TNF-related apoptosis-inducing ligand (TRAIL)-engineered MSCs on hepatocellular carcinoma (HCC) cells (HepG2) under different cultur...

journal_title：Anticancer research

authors： Sun XY,Nong J,Qin K,Lu H,Moniri MR,Dai LJ,Warnock GL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Chemotherapeutic anticancer properties are thought to derive from apoptosis pathway activation and/or cell division arrest, but animal models have also evidenced anti-angiogenic activity in some agents. PATIENTS AND METHODS:The impact of gemcitabine, irinotecan and oxaliplatin + 5-FU upon the serum markers ...

journal_title：Anticancer research

authors： Bellone G,Novarino A,Chiappino I,Gramigni C,Carbone A,Addeo A,Tonel E,Bertetto O,Emanuelli G

更新日期：2005-09-01 00:00:00

abstract：:Vitamin D is a steroid hormone traditionally recognized for maintaining calcium and phosphorous homeostasis in the body. However, it is now widely accepted that it exerts several extraskeletal actions, including anti-tumorigenic and immunomodulatory effects in vitro and in vivo. There is now a huge interest in studyin...

journal_title：Anticancer research

authors： Norton R,O'Connell MA

更新日期：2012-01-01 00:00:00

abstract：:The content, composition and physicochemical characteristics of glycosaminoglycans in human rectum and rectum carcinoma were investigated by chemical analyses, enzymic treatments, chromatographic and electrophoretic techniques. The overall glycosaminoglycan content was increased about 2 fold in neoplastic tissues comp...

journal_title：Anticancer research

authors： Tsara ME,Papageorgacopoulou N,Karavias DD,Theocharis DA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND/AIM:Chemotherapy-associated toxicity is one of the limiting factors regarding treatment efficacy, patient outcome and quality of life in this collective. Underweight or obese patients represent a major group in which the therapy seems to be more challenging. The aim of this analysis was to evaluate the impac...

journal_title：Anticancer research

authors： Grabowski JP,Richter R,Rittmeister H,Chekerov R,Woopen H,Sehouli J

更新日期：2018-10-01 00:00:00

abstract：:The significance of time interval for administration of a second drug after a first dose of cyclophosphamide (CTX) was studied for a human ovarian, lung, and colon carcinoma line growing as xenografts in nude mice. The effects of combination of two drugs were found to be dependent on the interval between the administr...

journal_title：Anticancer research

authors： Mattern J,Wauss K,Volm M

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND/AIM:We aimed to investigate the efficacy of immune-cell therapy in terms of the survival of patients with neuroendocrine carcinoma of the uterine cervix (NECC), which lacks standardized therapeutic approaches. PATIENTS AND METHODS:We identified 17 patients who were diagnosed as having NECC and treated with ...

journal_title：Anticancer research

authors： Goto S,Terao Y,Kamigaki T,Takimoto R,Naitoh K,Makita K,Yasumoto K,Okada S,Takizawa K,Yokomichi N,Suzuki N,Takeda S

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Lung cancer is the second leading cause of mortality among men and women in the U.S. Among different varieties of lung cancer, the non-small cell lung cancer (NSCLC) has the highest frequency comprising about 85% of cases. We evaluated 1-methyl-4-phenylpyridinium ion (MPP(+)) for cytotoxicity against human l...

journal_title：Anticancer research

authors： Badisa RB,Mina DA,Latinwo LM,Soliman KF

更新日期：2014-10-01 00:00:00

abstract：:There is sparse information about cancer in the axillary tail of Spence (CATS). Eight hundred and thirty-nine patients with breast cancer were retrospectively studied for the occurrence of CATS. Ten patients were identified based on detection by imaging studies. A tendency towards stage II or III disease, and estrogen...

journal_title：Anticancer research

authors： Ampil F,Caldito G,Henderson B,Li B,Kim RH,Burton G,Chu Q

更新日期：2012-09-01 00:00:00

abstract：:Eighty one patients with breast cancer stages I, II and III (T3a) were given adjuvant treatment with tamoxifen (Nolvadex), chemotherapy, or both. Most patients had estrogen and progesterone receptors measurement. Twenty one (63.6%) patients of the tamoxifen group were node positive, all 25 (100%) of the chemotherapy p...

journal_title：Anticancer research

authors： Marchei P,Bianco V,Pignatelli E,Chiodini S,Santini D,Carico E,Marchei M,Vecchione A

更新日期：1996-03-01 00:00:00

abstract：:Three sublines have been derived from the parental line Mv1Lu by transfection with normal and mutated Ha-ras, and myc oncogenes, and subsequent cloning. All the oncogenes have increased the growth rate of the cell in vitro, increased their plating efficiency in monolayer and suspension, and reduced their serum depende...

journal_title：Anticancer research

authors： Khan MZ,Spandidos DA,Kerr DJ,McNicol AM,Lang JC,De Ridder L,Freshney RI

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND/AIM:Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a rare autosomal dominant disorder characterized by fumarate hydratase (FH) gene mutation. It is associated with the development of very aggressive kidney tumors, characterized by early onset and high metastatic potential, and has no effective...

journal_title：Anticancer research

authors： Perrier-Trudova V,Huimin BW,Kongpetch S,Huang D,Ong P,Le Formal A,Poon SL,Siew EY,Myint SS,Gad S,Gardie B,Couvé S,Foong YM,Choudhury Y,Poh J,Ong CK,Toh CK,Ooi A,Richard S,Tan MH,Teh BT

更新日期：2015-12-01 00:00:00

abstract：:In order to identify genes associated with metastasis of mammary carcinoma, we compared the transcriptional profile (Affymetrix chip technology) of two cell lines derived from primary mammary carcinoma, three cell lines derived from bone marrow micrometastasis, a cell line derived from a lymph node metastasis as well ...

journal_title：Anticancer research

authors： Evtimova V,Schwirzke M,Tarbé N,Burtscher H,Jarsch M,Kaul S,Weidle UH

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND/AIM:Oral cancer represents approximately 2.5% of all cancers in the United States, with five- and 10-year survival rates of 62% and 51%. In the present study, lyophilized strawberries (LS) were evaluated for their potential to inhibit tumorigenesis in the hamster cheek pouch (HCP) model of oral cancer and fo...

journal_title：Anticancer research

authors： Casto BC,Knobloch TJ,Galioto RL,Yu Z,Accurso BT,Warner BM

更新日期：2013-11-01 00:00:00