Abstract:
:The effects of sensory stimulation on the release of amino acids from sensori-motor and visual cortices have been studied using a superfusion technique. Electrical stimulation of the brachial plexus contra-lateral to the superfusion cannula increased significantly the release of glutamate and glutamine from the sensori-motor cortex of anesthetized rats. No clear effect was observed with the other amino acids. Stimulation of the ipsi-lateral plexus had no effect on glutamate and glutamine release. In unanesthetized animals, stimulation of the contra-lateral brachial plexus raised the levels of all the amino acids in sensori-motor cortex superfusate. Weak photic stimulation of the eyes of dark-adapted rats increased glutamate release from the visual cortex but caused no significant change in the release of other amino acids. All evoked increases in amino acid release were reversible at the cessation of the stimuli.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Abdul-Ghani AS,Bradford HF,Cox DW,Dodd HFdoi
10.1007/978-1-4899-5199-1_15subject
Has Abstractpub_date
1979-01-01 00:00:00pages
251-67eissn
0065-2598issn
2214-8019journal_volume
123pub_type
杂志文章abstract::Changes in tumor tissue oxygenation and acidity were determined using ultramicroelectrodes, and presented in histogram fashion. The effect of Hyperthermia and Hpd photo-therapy were tested. It was found that both modalities affect tumor microcirculation, causing a marked drop in oxygen availability. Tissue pH is decre...
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