Effects of varying case definition on carpal tunnel syndrome prevalence estimates in a pooled cohort.

Abstract:

OBJECTIVE:To analyze differences in carpal tunnel syndrome (CTS) prevalence using a combination of electrodiagnostic studies (EDSs) and symptoms using EDS criteria varied across a range of cutpoints and compared with symptoms in both ≥1 and ≥2 median nerve-served digits. DESIGN:Pooled data from 5 prospective cohorts. SETTING:Hand-intensive industrial settings, including manufacturing, assembly, production, service, construction, and health care. PARTICIPANTS:Employed, working-age participants who are able to provide consent and undergo EDS testing (N=3130). INTERVENTIONS:None. MAIN OUTCOME MEASURES:CTS prevalence was estimated while varying the thresholds for median sensory latency, median motor latency, and transcarpal delta latency difference. EDS criteria examined included the following: median sensory latency of 3.3 to 4.1 milliseconds, median motor latency of 4.1 to 4.9 milliseconds, and median-ulnar sensory difference of 0.4 to 1.2 milliseconds. EDS criteria were combined with symptoms in ≥1 or ≥2 median nerve-served digits. EDS criteria from other published studies were applied to allow for comparison. RESULTS:CTS prevalence ranged from 6.3% to 11.7%. CTS prevalence estimates changed most per millisecond of sensory latency compared with motor latency or transcarpal delta. CTS prevalence decreased by 0.9% to 2.0% if the criteria required symptoms in 2 digits instead of 1. CONCLUSIONS:There are meaningful differences in CTS prevalence when different EDS criteria are applied. The digital sensory latency criteria result in the largest variance in prevalence.

journal_name

Arch Phys Med Rehabil

authors

Thiese MS,Gerr F,Hegmann KT,Harris-Adamson C,Dale AM,Evanoff B,Eisen EA,Kapellusch J,Garg A,Burt S,Bao S,Silverstein B,Merlino L,Rempel D

doi

10.1016/j.apmr.2014.08.004

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

2320-6

issue

12

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(14)01001-6

journal_volume

95

pub_type

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