Abstract:
OBJECTIVE:To evaluate changes in temporospatial gait parameters after intrathecal baclofen (ITB) bolus administration in patients with spasticity resulting from acquired brain injury by using computerized gait analysis. DESIGN:Case series; before-after intervention. Walking performance and spasticity in lower-extremity muscles were assessed before and at 2, 4, and 6 hours after ITB bolus injection. SETTING:Tertiary care free-standing rehabilitation hospital. PARTICIPANTS:Consecutive sample of 28 adults with acquired brain injury due to stroke, trauma, or anoxia. INTERVENTION:A 50-microg ITB bolus injection (2 subjects received 75 microg and 100 microg, respectively). MAIN OUTCOME MEASURES:Ashworth Scale scores, self-selected gait velocity, stride length, cadence, step length symmetry, step width, and percentage of single support on the more involved side. RESULTS:Ashworth score decreased from 2.0+/-0.5 at baseline to 1.3+/-0.3 at peak response ( P <.001), whereas gait velocity increased from 41+/-26 to 47+/-31 cm/s ( P <.001). Significant improvements also occurred in stride length ( P <.05) and step width ( P <.001). Gait velocity was the most sensitive temporospatial outcome measure for differentiating functional response to ITB bolus injection. Sixteen patients increased velocity by an average of 12 cm/s, representing a mean gain of 33% over their baseline walking speed, while 5 decreased (mean loss, -6 cm/s [52% of baseline]) and 7 were unchanged. There was a significant correlation between baseline velocity and peak change in velocity after ITB bolus ( r =.39, P <.05). Baseline Ashworth score correlated inversely with velocity, stride length, cadence, and percentage single support (r range, -.46 to -.57). No significant correlations were found between change in Ashworth score and change in any temporospatial outcome measure. CONCLUSIONS:ITB bolus injection consistently reduces spasticity in ambulatory patients with acquired brain injury but may result in a range of changes in walking performance that can be reliably detected using computerized motion analysis. Velocity appears to be the most sensitive parameter with which to classify individual patient response. The relation between baseline gait velocity and peak change in velocity after bolus administration may have application in predicting the outcome of screening trials for pump implantation; it warrants further investigation.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Horn TS,Yablon SA,Stokic DSdoi
10.1016/j.apmr.2004.11.013subject
Has Abstractpub_date
2005-06-01 00:00:00pages
1127-33issue
6eissn
0003-9993issn
1532-821Xpii
S0003-9993(05)00015-8journal_volume
86pub_type
临床试验,杂志文章abstract:OBJECTIVE:To investigate the effects of combination cathodal transcranial direct current stimulation (tDCS) and virtual reality (VR) therapy for upper extremity (UE) training in patients with subacute stroke. DESIGN:Pilot randomized controlled trial. Patients were randomly assigned to 1 of 3 groups: group A received c...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.apmr.2013.10.027
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:To investigate changes in axonal flow after nerve root compression by using immunohistochemical techniques to detect calcitonin gene-related peptide (CGRP), which is thought to be involved in pain sensation. DESIGN:Experimental, controlled study. SETTING:University medical school in Japan. ANIMALS:Forty ad...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2004.03.037
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:To investigate the physiologic differences during multispeed treadmill walking and physical activity profiles for the Otto Bock C-Walk foot (C-Walk), Flex-Foot, and solid ankle cushion heel (SACH) foot in people with transtibial amputation. DESIGN:A repeated-measures design with 3 prostheses. SETTING:Resear...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2005.07.310
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to analyze the ability of the patients with idiopathic scoliosis to transfer the body weight in the frontal plane. DESIGN:Randomized and controlled study. SETTING:A referral center and institutional practice and outpatient care. SUBJECTS:Fifty patients with idiopathic scolios...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0003-9993(95)80630-x
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:To determine whether regular performance of adapted sports is associated with long-term changes in carotid atherosclerosis in subjects with spinal cord injury (SCI). DESIGN:Prospective observational study. SETTING:Academic medical center. PARTICIPANTS:Men with chronic (>1y) SCI and no preserved motor funct...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2015.11.002
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To describe group therapy utilization in spinal cord injury (SCI) inpatient rehabilitation. DESIGN:Prospective observational study. SETTING:Six inpatient rehabilitation facilities. PARTICIPANTS:Patients (N=1376) receiving initial rehabilitation after traumatic SCI. INTERVENTIONS:Not applicable. MAIN OUTC...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,多中心研究
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更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To compare 3-dimensional (3D) shoulder joint reaction forces and stride characteristics during bilateral forearm crutches and front-wheeled walker ambulation in persons with incomplete spinal cord injury (SCI). DESIGN:Cross-sectional cohort study. SETTING:Biomechanics laboratory. PARTICIPANTS:Fourteen adul...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2005.07.311
更新日期:2006-01-01 00:00:00
abstract:UNLABELLED:Baer GD, Smith MT, Rowe PJ, Masterton L. Establishing the reliability of mobility milestones as an outcome measure for stroke. Arch Phys Med Rehabil 2003;84:977-81. OBJECTIVE:To establish intrarater, interrater, and test-retest reliability of a standardized measure of mobility, "mobility milestones," incorp...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(03)00050-9
更新日期:2003-07-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1984-06-01 00:00:00
abstract:OBJECTIVE:To determine if a single, over-the-counter dose of the H1 antagonist chlorpheniramine maleate (CM) alters total peripheral resistance (TPR) and oxygen uptake (VO2) during submaximal exercise. DESIGN:The study was a prospective, longitudinal, double-blind, random crossover analysis of the cardiovascular and r...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0003-9993(98)90365-3
更新日期:1998-07-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1016/j.apmr.2014.04.007
更新日期:2014-09-01 00:00:00
abstract::Establishing treatment effectiveness is a high priority for rehabilitation research. The use of traditional quantitative null hypotheses to achieve this priority is reviewed. Three problems are identified in the analysis and interpretation of investigations based on statistical testing of hypotheses: (1) confusion of ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(95)80021-2
更新日期:1995-02-01 00:00:00
abstract::The halo traction device for cervical spine immobilization has few complications and is routinely used for spinal cord injured patients. The following case report describes a patient with lower cervical and upper thoracic fractures stabilized with a halo. She completed a two-month rehabilitation program without compli...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract:OBJECTIVE:To derive a normative database for nerve conduction values of the lateral antebrachial cutaneous nerve (LACN) using a large and varied subject population. DESIGN:Descriptive study. SETTING:Private office or university-based clinic. PARTICIPANTS:Volunteers (n = 213), recruited through advertisements, who me...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1053/apmr.2000.9394
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of ramelteon on sleep and daytime functioning among individuals with traumatic brain injury (TBI). DESIGN:A double-blind, placebo-controlled study with a crossover design. SETTING:A research facility attached to an acute rehabilitation hospital. PARTICIPANTS:Individuals with TBI (...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.apmr.2015.05.011
更新日期:2015-10-01 00:00:00
abstract::Cortical somatosensory evoked potential (CSEP) examinations were performed of 20 patients with lumbar spinal stenosis a day prior to surgery and 10 to 12 days after spinal decompression and bilateral lateral fusion. CSEPs were recorded to Cz-Fz (10-20 international EEG system) following stimulation of 32 tibial, peron...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2007.07.047
更新日期:2008-01-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2009.08.153
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To validate a novel assessment of inpatient physical activity. DESIGN:Prospective cohort study for the evaluation of a novel questionnaire for physical activity in geriatric inpatients. SETTING:German geriatric inpatient rehabilitation unit. PARTICIPANTS:Patients (N=96; 67 [72%] women; median age, 81y) wit...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2011.06.032
更新日期:2011-12-01 00:00:00
abstract::Twenty-seven normal, healthy women participated in this study, which investigated three methods of increasing the isometric strength of the quadriceps femoris through a six-week training program. Three experimental exercise groups were formed: A, eccentric, B, concentric, and C, isometric. The peak isometric torque of...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract:OBJECTIVE:To determine bone mineral density (BMD) z scores in adults with cerebral palsy (CP), an understudied population. DESIGN:Cross-sectional. SETTING:Medical facility. PARTICIPANTS:Adults (N=48; mean age, 34.3±5.8y; range, 25-46y) with CP. INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:BMD z scores at th...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2015.03.012
更新日期:2015-07-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.apmr.2004.09.018
更新日期:2005-05-01 00:00:00
abstract::To study the relationship between isokinetic and isometric torque, maximum voluntary contractions were elicited from 352 male volunteers. Knee extensors, knee flexors, elbow extensors, and elbow flexors were tested isometrically and at isokinetic velocities of 30 degrees/sec, 90 degrees/sec, and 180 degrees/sec on a m...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVES:To measure the changes in the total and regional body fat mass, and assess the clinical usefulness of the body mass index (BMI) in detecting overweight subjects with sequelae of poliomyelitis. DESIGN:Prospective, cross-sectional study. SETTING:General community. PARTICIPANTS:Subjects with poliomyelitis (n...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2011.01.019
更新日期:2011-07-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2015.10.089
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To assess the effects on functional outcomes and treatment adherence of wearable technology and serious games (ie, interactive computer applications with specific purposes useful in the "real world") currently used in physical rehabilitation of patients after traumatic bone and soft tissue injuries. DATA SOU...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2017.10.018
更新日期:2018-09-01 00:00:00
abstract::The purpose of this case study was to determine whether an individual who had residual deficits following an acute incidence of Guillain-Barre Syndrome (GBS) would experience improved physiological adaptations following aerobic endurance training. A 57-year-old man who needed the aid of a crutch for walking three year...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/0003-9993(93)90039-d
更新日期:1993-07-01 00:00:00
abstract:OBJECTIVE:To present preliminary data on the health-related consequences for people with spinal cord injury (SCI) of participation in a prepaid, risk-based, managed care plan. DESIGN:Baseline data from a longitudinal interview survey. SETTING:Massachusetts. PARTICIPANTS:Subjects were 114 independently living adults ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(99)90257-5
更新日期:1999-11-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1016/s0003-9993(99)90133-8
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:To assess participation rates and outcome in outpatient cardiac rehabilitation (OCR) of patients with peripheral arterial occlusive disease (PAOD). DESIGN:Prospective cohort study. SETTING:Referral center, ambulatory care. PARTICIPANTS:All patients undergoing OCR at 2 university hospitals in Switzerland fr...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2007.09.040
更新日期:2008-04-01 00:00:00