Recovery of embolized albumin microspheres from the pulmonary microvasculature using a wedged balloon-tipped catheter.

abstract：OBJECTIVE:Our intent was to evolve a prognosticator that would predict the likelihood that an electrical shock would restore a perfusing rhythm. Such a prognosticator was to be based on conventional electrocardiographic signals but without constraints caused by artifacts resulting from precordial compression. The adver...

journal_title：Critical care medicine

authors： Marn-Pernat A,Weil MH,Tang W,Pernat A,Bisera J

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:Monocytes and macrophages produce interleukin-1β by inflammasome activation which involves adenosine triphosphate release, pannexin-1 channels, and P2X7 receptors. However, interleukin-1β can also be produced in an inflammasome-independent fashion. Here we studied if this mechanism also involves adenosine tr...

journal_title：Critical care medicine

authors： Lee AH,Ledderose C,Li X,Slubowski CJ,Sueyoshi K,Staudenmaier L,Bao Y,Zhang J,Junger WG

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:Our goal was to "reverse translate" the human response to surgical sepsis into the mouse by modifying a widely adopted murine intra-abdominal sepsis model to engender a phenotype that conforms to current sepsis definitions and follows the most recent expert recommendations for animal preclinical sepsis resea...

journal_title：Critical care medicine

authors： Stortz JA,Hollen MK,Nacionales DC,Horiguchi H,Ungaro R,Dirain ML,Wang Z,Wu Q,Wu KK,Kumar A,Foster TC,Stewart BD,Ross JA,Segal M,Bihorac A,Brakenridge S,Moore FA,Wohlgemuth SE,Leeuwenburgh C,Mohr AM,Moldawer LL,E

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Restoration of myocardial blood flow after ischemia triggers an inflammatory response involving toll-like receptors. Toll-like receptor 2 deficiency is associated with a reduced infarct size after myocardial ischemia and reperfusion. Because a marked mortality was observed in C3HeN wild-type mice, which was a...

journal_title：Critical care medicine

authors： Mersmann J,Koch A,Tran N,Zimmermann R,Granja TF,Larmann J,Herzog C,Theilmeier G,Bornstein SR,Kirschning CJ,Zacharowski K

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:Although the majority of sudden cardiac arrests occur in patients with ischemic heart disease, the effect of therapeutic hypothermia on arrhythmia susceptibility during acute global ischemia is not well understood. While both ischemia and severe hypothermia are arrhythmogenic, patients undergoing therapeutic...

journal_title：Critical care medicine

authors： Piktel JS,Rosenbaum DS,Wilson LD

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:This study determined the time course for inhibition of lipopolysaccharide-induced acute lung injury following a single dose of genistein. In addition, the study investigated whether a multiple dosing schedule with genistein retained the inhibitory effects on acute lung injury, nuclear factor-kappaB activatio...

journal_title：Critical care medicine

authors： Kang JL,Lee HW,Lee HS,Pack IS,Castranova V,Koh Y

更新日期：2003-02-01 00:00:00

abstract：:To determine the influence of arachidonic acid metabolites on acute lung injury induced by glass bead embolism, two groups of animals were studied before and after the pulmonary artery pressure was doubled by glass bead embolism. One group represented an untreated time control (n = 6) while the second group (n = 6) wa...

journal_title：Critical care medicine

authors： Calvin JE,Dervin G

更新日期：1988-09-01 00:00:00

abstract：:Twenty-one patients who underwent cardiopulmonary bypass for myocardial revascularization received postoperatively controlled mechanical ventilation (CMV) or intermittent mandatory ventilation (IMV), with or without positive end-expiratory pressure (PEEP). Functional residual capacity (FRC), right-to-left intrapulmona...

journal_title：Critical care medicine

authors： Downs JB,Mitchell LA

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVE:Effective therapies are needed to reverse the increased vascular permeability that characterizes acute inflammatory diseases such as acute lung injury. FTY720 is a pharmaceutical analog of the potent barrier-enhancing phospholipid, sphingosine 1-phosphate. Because both FTY720 and sphingosine 1-phosphate have ...

journal_title：Critical care medicine

authors： Wang L,Sammani S,Moreno-Vinasco L,Letsiou E,Wang T,Camp SM,Bittman R,Garcia JG,Dudek SM

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:To provide an overview of key elements of the Affordable Care Act. To evaluate ways in which the Affordable Care Act will likely impact the practice of critical care medicine. To describe strategies that may help health systems and providers effectively adapt to changes brought about by the Affordable Care A...

journal_title：Critical care medicine

authors： Dogra AP,Dorman T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:We reviewed randomized trials of adult ICU patients of interventions hypothesized to reduce delirium burden to determine whether interventions that are more effective at reducing delirium duration are associated with a reduction in short-term mortality. DATA SOURCES:We searched CINHAHL, EMBASE, MEDLINE, and...

journal_title：Critical care medicine

authors： Al-Qadheeb NS,Balk EM,Fraser GL,Skrobik Y,Riker RR,Kress JP,Whitehead S,Devlin JW

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Trauma induces a complex immune response that requires a systems biology research approach. Here, we used a novel technology, mass cytometry by time-of-flight, to comprehensively characterize the multicellular response to trauma. DESIGN:Peripheral blood mononuclear cells samples were stained with a 38-marker...

journal_title：Critical care medicine

authors： Seshadri A,Brat GA,Yorkgitis BK,Keegan J,Dolan J,Salim A,Askari R,Lederer JA

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:To describe the impact of choice of therapy on renal recovery. DESIGN:Literature review. MAIN RESULTS:Randomized controlled trials conducted have not shown a benefit of continuous renal replacement therapy in mortality over intermittent renal replacement therapy. However, renal recovery is another importan...

journal_title：Critical care medicine

authors： Uchino S

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:To develop a predictive equation to estimate the frequency of blood drawing for intensive care unit (ICU) laboratory tests and to evaluate variations in ICU blood sampling practices after adjusting for patient and institutional factors. DESIGN:Prospective, inception, cohort study. SETTING:Forty-two ICUs in...

journal_title：Critical care medicine

authors： Zimmerman JE,Seneff MG,Sun X,Wagner DP,Knaus WA

更新日期：1997-05-01 00:00:00

abstract：:Intermittent Mandatory Ventilation (IMV) provides an alternative method of support to assisted and controlled mechanical ventilation in neonates with acute respiratory failure. Specific advantages include the use of only the level of mechanical support which is required on an individual basis. Because intrapleural pre...

journal_title：Critical care medicine

authors： Kirby RR

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To determine the association between symptomatic central venous line-related deep venous thrombosis and a mortality-adjusted measure of duration of mechanical ventilation in critically ill children with central venous lines. DESIGN:Retrospective matched cohort study. SETTING:Eleven pediatric intensive care ...

journal_title：Critical care medicine

authors： Faustino EV,Lawson KA,Northrup V,Higgerson RA

更新日期：2011-05-01 00:00:00

abstract：:Hemodynamic effects of iso-oncotic 3% dextran-60, 6% dextran-70, and Ringer's acetate were compared in 28 male pigs (25 to 30 kg) subjected to experimental trauma and hemorrhage. The animals were kept anesthetized with 75% N2O/25% O2, 0.8% halothane. Hemodynamic and respiratory conditions were allowed to stabilize for...

journal_title：Critical care medicine

authors： Schött U,Lindbom LO,Sjöstrand U

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:Acute lung injury with subsequent pneumonia and sepsis represents a major cause of morbidity and mortality in thermally injured patients. Production of nitric oxide by the neuronal and inducible nitric oxide synthase may be critically involved in the pathophysiology of the disease process at different time po...

journal_title：Critical care medicine

authors： Lange M,Connelly R,Traber DL,Hamahata A,Cox RA,Nakano Y,Bansal K,Esechie A,von Borzyskowski S,Jonkam C,Traber LD,Hawkins HK,Herndon DN,Enkhbaatar P

更新日期：2009-01-01 00:00:00

abstract：:Critical Care Medicine encompasses an extremely broad scope. Examination questions were, therefore, chosen to cover a wide variety of critical care topics. A near Gaussian distribution of scores was found for all physician groups studied. We believe the low mean score of 15% reflects the general difficulty of the exam...

journal_title：Critical care medicine

authors： Veremakis C,Taylor RW

更新日期：1983-05-01 00:00:00

abstract：:The disadvantages of external ventricular drainage are the threat of sepsis and the nuisance of dislodging a precarious system in routine care. The experience of the authors with nearly 200 cases using a long ventricular catheter demonstrates that a subgaleal tunnel can be easily made for the ventricular catheter usin...

journal_title：Critical care medicine

authors： Saunders RL,Lyons TA

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the hypocalcemia and hypoparathyroidism that follow severe burn injury are related to up-regulation of the parathyroid gland calcium-sensing receptor (CaR), which may reduce the set-point for suppression of circulating parathyroid hormone by blood calcium. DESIGN:A controlled but ...

journal_title：Critical care medicine

authors： Murphey ED,Chattopadhyay N,Bai M,Kifor O,Harper D,Traber DL,Hawkins HK,Brown EM,Klein GL

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Cytokine response after cardiac surgery may be genetically influenced. A study was carried out to investigate the relation between cytokine gene expression in peripheral blood mononuclear cells, genotype, and clinical events after cardiac surgery. DESIGN:A case-control study was performed. SETTING:Cardiac i...

journal_title：Critical care medicine

authors： Duggan E,Caraher E,Gately K,O'Dwyer M,McGovern E,Kelleher D,McManus R,Ryan T

更新日期：2006-08-01 00:00:00

abstract：:The venous-arterial PCO2 gradient may increase in certain low-flow states, such as CPR and canine endotoxemia. To determine whether venous hypercarbia also occurs in hemorrhagic shock, we studied 12 anesthetized, mechanically ventilated dogs. We performed laparotomies on the animals, inserting catheters into their ren...

journal_title：Critical care medicine

authors： Benjamin E,Paluch TA,Berger SR,Premus G,Wu C,Iberti TJ

更新日期：1987-05-01 00:00:00

abstract：:Among Gram-positive pathogens, Staphylococcus aureus is the leading cause of death from nosocomial pneumonia. The bacterium developed progressive resistance to beta-lactams, and methicillin-resistant strains emerged in the 1980s. In consequence, vancomycin has become the drug of choice for treatment of this infection ...

journal_title：Critical care medicine

authors： Bodi M,Ardanuy C,Rello J

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To test whether there is a circadian rhythm of blood glucose control in critically ill patients and whether morning blood glucose is an accurate surrogate of overall blood glucose control. DESIGN:Retrospective multiple-center observational study. SETTING:Intensive care units of three tertiary hospitals and ...

journal_title：Critical care medicine

authors： Egi M,Bellomo R,Stachowski E,French CJ,Hart G,Stow P

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to determine whether selective inflammatory cytokine concentrations within cerebrospinal fluid are useful markers for the differential diagnosis of aseptic and bacterial meningitis within neurosurgical patients. DESIGN:Prospective, open-label, observational, cohort stud...

journal_title：Critical care medicine

authors： Liu ZH,Tu PH,Chen NY,Yip PK,Bowes AL,Lee CC,Chan SH,Kung CC,Wang AY,Wu CT,Lee ST

更新日期：2015-11-01 00:00:00

abstract：:Percutaneous cholecystostomy was employed successfully as an alternative to cholecystectomy for the treatment of acute cholecystitis with perforation in an elderly woman. The procedure, performed portably in the cardiac care unit, was selected because progressive cardiac and renal decompensation made the patient an ex...

journal_title：Critical care medicine

authors： Longmaid HE 3rd,Bassett JG,Gottlieb H

更新日期：1985-08-01 00:00:00

abstract：:Recorded values (SpO2) of oxygen saturation from six noninvasive pulse oximeters were compared to each other and to the value from a cooximeter. Simultaneous measurements were obtained from each instrument in eight healthy nonsmoking volunteers rendered hypoxic greater than 70% SpO2. Functional arterial oxygen saturat...

journal_title：Critical care medicine

authors： Choe H,Tashiro C,Fukumitsu K,Yagi M,Yoshiya I

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVES:Measurement of blood lactate concentration in the early management of sepsis is an important step in severity assessment. High blood lactate levels in the early phase of sepsis have classically been thought to be related to tissue hypoxia, but other factors could intervene. We hypothesized that the activatio...

journal_title：Critical care medicine

authors： Contenti J,Occelli C,Corraze H,Lemoël F,Levraut J

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:To compare the frequency and preventability of adverse drug events and potential adverse drug events in intensive care units (ICUs) and non-ICUs. To evaluate systems factors involving the individual caregivers, care unit teams, and patients involved in each adverse drug event by comparing ICUs with non-ICUs ...

journal_title：Critical care medicine

authors： Cullen DJ,Sweitzer BJ,Bates DW,Burdick E,Edmondson A,Leape LL

更新日期：1997-08-01 00:00:00