[Prophylaxis of gallstone formation (author's transl)].

Abstract:

:Today we know the pathobiochemical mechanism of gallstone formation. Cholecystectomy is the therapy of choice with a mortality-rate 0,5% in uncomplicated cases. The mortality-rate increases in patients with recurrent stones in the biliary tract system after cholecystectomy. In addition the liver produces a lithogenic bile. We propose the prophylactic use of chenodesocycholic acid in patients after choledochal revision, if the bile duct system is altered in such a way that cholesterol crystals can aggregate and grow to stones. A low dose of cheno acid is sufficient. Moreover a fibre rich diet increases the chenodesoxycholic acid synthesis in the liver.

journal_name

Zentralbl Chir

authors

Stremmel W

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

162-6

issue

3

eissn

0044-409X

issn

1438-9592

journal_volume

105

pub_type

杂志文章
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