The treatment of Wilms' tumor: results from Royal Children's Hospital, Melbourne, 1967-1977.

Abstract:

:A retrospective review of the treatment of Wilms' tumor from 1967 to 1977 at the Royal Children's Hospital, Melbourne, was undertaken, allowing a minimum 2-yr followup. Fifty-four (77%) of the 70 patients in the study are alive, with 23/25 (92%) in Stage I, 12/16 (75%) in Stage II, 12/19 (63%) in Stage III, and 7/9 (78%) in Stage IV. Survival was significantly better in Stage I disease, and those patients less than 5-yr-old at presentation. Recurrence of disease was significantly lower after the introduction of multiple courses of chemotherapy in 1971. Sixteen deaths occurred during the period: three infants from drug toxicity, four patients with "unfavorable" sarcomatous histology, and four patients with recurrent local disease, where irradiation had been confined to the tumor bed after tumor spill with recurrence beyond the irradiated field.

journal_name

J Pediatr Surg

authors

Hutson JM,Kent M,Ekert H,Waters KD

doi

10.1016/s0022-3468(83)80091-8

subject

Has Abstract

pub_date

1983-06-01 00:00:00

pages

235-9

issue

3

eissn

0022-3468

issn

1531-5037

pii

S0022346883000433

journal_volume

18

pub_type

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