Abstract：
OBJECTIVE:The objective of the study was to determine factors predicting outcome in newborns with gastroschisis. METHODS:A retrospective analysis of 155 consecutive cases admitted from 1 January 1990 to 31 December 2007 was performed. Prenatal ultrasound findings were available for 89 of 155 (57%) patients and were compared with final outcome. Both univariate and multiple regression analyses were used. RESULTS:All patients survived to discharge home. The primary outcome measure was length of stay. Multiple regression identified 4 factors associated with length of stay: (1) gestational age (P = .004), (2) nonelective silo (P < .001), (3) gastrointestinal (GI) complication (intestinal atresia, perforation, or resection) (P < .001), and (4) non-GI anomaly (P = .029). Non-GI anomalies occurred in 17 of 155 (11%) patients and tended to increase the risk of a nonelective silo or GI complication (59% vs 39%, P = .190). Dilated bowel (>10 mm) on prenatal ultrasound was associated with GI complications (22% vs 3%, P = .010). However, 78% of patients with dilated bowel on prenatal ultrasound did not have a GI complication. The absence of dilated bowel on prenatal ultrasound accurately predicted the absence of GI complications in 97% of cases. CONCLUSION:Prematurity, nonelective silo, GI complications, and non-GI anomalies predict the short-term outcome of newborns with gastroschisis. Prenatal ultrasound serves primarily to predict the absence of GI complications.
journal_name
J Pediatr Surgjournal_title
Journal of pediatric surgeryauthors
Payne NR,Pfleghaar K,Assel B,Johnson A,Rich RHdoi
10.1016/j.jpedsurg.2009.01.036subject
Has Abstractpub_date
2009-05-01 00:00:00pages
918-23issue
5eissn
0022-3468issn
1531-5037pii
S0022-3468(09)00051-7journal_volume
44pub_type
杂志文章abstract：:The ideal surgical closure for large omphaloceles remains controversial. Most techniques described advocate removal of the amniotic sac prior to repair of the abdominal wall defect. Herein, the authors describe a surgical technique preserving the amniotic sac, which has distinct advantages in achieving safe and rapid ...
journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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abstract：BACKGROUND:Flap closure represents an alternative to fascial closure for gastroschisis. We performed a systematic review and meta-analysis of outcomes comparing these techniques. METHODS:A registered systematic review ( PROSPERO:CRD42015016745) of comparative studies was performed, querying multiple databases without...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章,meta分析,评审
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/0022-3468(92)90446-e
更新日期：1992-05-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(96)90663-6
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journal_title：Journal of pediatric surgery
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更新日期：1981-06-01 00:00:00
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/0022-3468(91)90511-q
更新日期：1991-03-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：1998-05-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：1991-02-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2004.02.049
更新日期：2004-06-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(79)80140-2
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2011.03.065
更新日期：2011-07-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1053/jpsu.2001.24754
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abstract：:Elective cesarean section (CS) following prenatal diagnosis of gastroschisis has been advocated to decrease morbidity and mortality. To examine this hypothesis, we reviewed the records of 28 consecutive patients with gastroschisis treated between 1975 and 1987. Fourteen infants were delivered vaginally (V) and fourtee...
journal_title：Journal of pediatric surgery
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pub_type： 临床试验,杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1053/jpsu.2001.27937
更新日期：2001-11-01 00:00:00
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更新日期：2012-04-01 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2014-06-01 00:00:00
abstract：PURPOSE:SIX2 and CITED1 are transcriptional regulators that specify self-renewing nephronic progenitor cells of the embryonic kidney. We hypothesized that SIX2, which promotes and maintains this stem cell population, and CITED1 remain active in Wilms' tumor (WT). METHODS:To evaluate expression domains and the pathogen...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：2017-06-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：2009-12-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(03)00203-3
更新日期：2003-07-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2010.06.033
更新日期：2010-11-01 00:00:00
