Case report: successful interdisciplinary treatment of cerebrally disseminated invasive pulmonal aspergillosis in a child with acute myeloid leukemia.

Abstract:

:Invasive pulmonary aspergillosis (IPA) is a life-threatening infection in immunocompromised patients. Mortality rates of cerebrally disseminated IPA approach 100%. We report on a case of a 9-year-old girl with acute myeloid leukemia, who acquired cerebrally disseminated IPA during chemotherapy-induced leukopenia. Longtime survival was achieved by left pneumonectomy and neurosurgical resection of the intracerebral lesion combined with systemic application of itraconazole and liposomal amphotericin B. A review of literature revealed 7 other cases of cerebrally disseminated IPA with survival of more than 12 months.

journal_name

J Pediatr Surg

authors

Kurdow R,Boehle AS,Ankermann T,Schniewind B,Dohrmann P

doi

10.1016/j.jpedsurg.2005.03.104

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

1191-4

issue

7

eissn

0022-3468

issn

1531-5037

pii

S0022346805002824

journal_volume

40

pub_type

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