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Comorbidity in obsessive-compulsive disorder (OCD): a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS).

Abstract：

BACKGROUND:Obsessive-compulsive disorder (OCD) is often associated with significant psychiatric comorbidity. Comorbid disorders include mood and anxiety disorders as well as obsessive-compulsive spectrum disorders (OCSDs). This paper aims to investigate comorbidity of DSM Axis I-disorders, including OCSDs, in patients with OCD from 10 centers affiliated with the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). METHODS:This is a cross-sectional study of comorbidity of Axis I disorders including OCSDs in 457 outpatients with primary OCD (37% male; 63% female), with ages ranging from 12 to 88years (mean: 39.8±13). Treating clinicians assessed Axis I disorders using the Mini International Neuropsychiatric Interview and assessed OCSDs using the Structured Clinical Interview for OCD related/spectrum disorders (SCID-OCSD). RESULTS:In terms of the OCSDs, highest comorbidity rates were found for tic disorder (12.5%), BDD (8.71%) and self-injurious behavior (7.43%). In terms of the other Axis I-disorders, major depressive disorder (MDD; 15%), social anxiety disorder (SAD; 14%), generalized anxiety disorder (GAD; 13%) and dysthymic disorder (13%) were most prevalent. DISCUSSION:High comorbidity of some OCSDs in OCD supports the formal recognition of these conditions in a separate chapter of the nosology. Rates of other Axis I disorders are high in both the general population and in OCSDs, indicating that these may often also need to be the focus of intervention in OCD.

journal_name

Compr Psychiatry

journal_title

Comprehensive psychiatry

authors

Lochner C,Fineberg NA,Zohar J,van Ameringen M,Juven-Wetzler A,Altamura AC,Cuzen NL,Hollander E,Denys D,Nicolini H,Dell'Osso B,Pallanti S,Stein DJ

doi

10.1016/j.comppsych.2014.05.020

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

1513-9

issue

7

eissn

0010-440X

issn

1532-8384

pii

S0010-440X(14)00145-X

journal_volume

55

pub_type

杂志文章

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