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Immunoglobulin light chains in common acute lymphoblastic leukaemia.

Abstract：

:A single immunoglobulin light chain lambda was identified in the blast cells of two out of 12 patients with common acute lymphoblastic leukaemia (C-ALL) using the alkaline phosphatase/anti-alkaline phosphatase (APAAP) technique. Inhibition at the cell surface proved that the reaction was a genuine anti-lambda reaction. Immunoglobulin mu chain was not identified in these patients. Results of immunoglobulin typing in 103 patients with B chronic lymphocytic leukaemia (B-CLL) are cited to show the increased sensitivity of the APAAP technique as compared to the indirect immunoperoxidase technique for cellular immunoglobulin identification.

journal_name

Br J Haematol

journal_title

British journal of haematology

authors

Markey GM,Alexander HD,Nolan RL,Morris TC,Robertson JH

doi

10.1111/j.1365-2141.1989.tb06274.x

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

53-5

issue

1

eissn

0007-1048

issn

1365-2141

journal_volume

71

pub_type

杂志文章

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