Detection of gastrointestinal blood loss with 99mTc-labeled, heat-treated red blood cells.

Abstract:

:Studies in dogs showed that heat-treated 99mTc-labeled red blood cells (HT/RBC) afford a highly sensitive means of detecting gastrointestinal bleeding as low as 0.12 ml/min., which could not be seen with unheated 99mTc-RBC, 99mTc-sulfur colloid, or 99mTc-DTPA. In addition, as the right upper quadrant and epigastrium remained free of activity, only one fifth to one tenth of the dose of 99mTc was needed. The safety of HT/RBC in humans has been documented, and the experiments in dogs suggest that it may have advantages over other agents in detecting gastrointestinal bleeding.

journal_name

Radiology

journal_title

Radiology

authors

Som P,Oster ZH,Atkins HL,Goldman AG,Sacker DF,Harold WH,Fairchild RG,Richards P,Brill AB

doi

10.1148/radiology.138.1.6969900

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

207-9

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

138

pub_type

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