Abstract:
PURPOSE:To assess the ability of positron emission tomography (PET) with 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) to allow differentiation of benign from malignant intraosseous lesions. MATERIALS AND METHODS:Twenty patients with strictly intraosseous lesions (five benign and 15 malignant [three primary and 12 metastatic]) were studied with FDG PET. The final diagnosis was confirmed with histopathologic examination in all patients. The uptake of FDG within each lesion was evaluated qualitatively as well as semiquantitatively by determination of the standardized uptake value (SUV). RESULTS:SUV assessment of FDG accumulation within osseous lesions was superior to subjective visual analysis for discriminating benign from malignant lesions. With use of a 2.0 cutoff value for SUV, 14 of 15 malignant lesions were categorized correctly versus 12 of 15 correctly categorized by means of subjective image evaluation; four of five benign lesions were categorized correctly with both techniques. CONCLUSION:FDG PET can aid in differentiating benign from malignant strictly intraosseous lesions.
journal_name
Radiologyjournal_title
Radiologyauthors
Dehdashti F,Siegel BA,Griffeth LK,Fusselman MJ,Trask DD,McGuire AH,McGuire DJdoi
10.1148/radiology.200.1.8657920subject
Has Abstractpub_date
1996-07-01 00:00:00pages
243-7issue
1eissn
0033-8419issn
1527-1315journal_volume
200pub_type
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