Abstract:
INTRODUCTION:Intraperitoneal chemotherapy preceded by cytoreductive surgery should be the standard of care in the treatment of advanced epithelial ovarian cancer. This combination has been extensively examined in both the clinical and preclinical settings with favourable oncologic outcomes. Unfortunately, despite the existence of these evidence-based data, this management strategy remains underutilised. MATERIALS AND METHODS:We review and discuss the role of intraperitoneal chemotherapy with particular emphasis about the pharmacokinetics and pharmacodynamics aspects, the mode of administration, the reported side effects, the compliance of the patients and the clinical ongoing studies. CONCLUSIONS:Further studies investigating the pharmacokinetics and pharmacodynamics aspect of IP route may help to reduce toxicity pending more effective treatments.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Grosso G,Rossetti D,Coccolini F,Bogani G,Ansaloni L,Frigerio Ldoi
10.1007/s00404-014-3252-2subject
Has Abstractpub_date
2014-09-01 00:00:00pages
425-34issue
3eissn
0932-0067issn
1432-0711journal_volume
290pub_type
杂志文章,meta分析,评审abstract:PURPOSE:To establish a reference range for the intracranial translucency (IT). METHODS:In this prospective study, we examined 596 singleton fetuses at 11-14 weeks of gestation using transabdominal ultrasonography. The distribution curves of the anterior-posterior diameter of the IT were established according to the ge...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3410-6
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:The purpose of the present study was to investigate the predictive power of sexual hormones and tumor markers in endometrial cancer. METHODS:A total of 135 healthy women were prospectively compared with 135 women who had histopathologically confirmed endometrial cancer. Both the groups of women were matched ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1228-4
更新日期:2010-04-01 00:00:00
abstract::Sirenomelia sequence is a very rare congenital malformation, with incidence of around 1.5-4.2 per 100,000 births. Prenatal diagnosis of sirenomelia in the first trimester is rare; there are only five cases reported for the present, and the association of sirenomelia with acardiac malformation is even rarer. We present...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0250-z
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the neovascularization in placental polyp tissue by computed tomographic angiography and to determine the need for uterine artery embolization before hysteroscopic resection. STUDY DESIGN:Seventeen consecutive women with suspected placental polyp were enrolled in this retrospective study. Neovasc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1161-6
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:More than 370 million women will experience recurrent vulvovaginal candidiasis (RVVC) during their lifetime. However, RVVC is often trivialized as clinically insignificant and not worthy of research funding. We evaluated the influence of RVVC on the quality of life in affected women. METHODS:The validated Worl...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05228-3
更新日期:2019-09-01 00:00:00
abstract::In the original article publication, the authors given name and family name were interchanged. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 已发布勘误
doi:10.1007/s00404-019-05279-6
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:Splenic metastasis from endometrial carcinoma is a rare clinical event, with only 11 cases documented previously in the literature. CASE REPORT:A 58-year-old woman had surgery and radiotherapy for stage IIB endometrial carcinoma. Eighteen months later, PET scan discovered a hypermetabolic splenic mass and...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1039-7
更新日期:2009-12-01 00:00:00
abstract::A 32 years old omani woman G6P4A1 at 39 weeks of pregnancy presented with complaints of headache and picture of eclampsia. Emergency caesarean section was done for maternal and foetal distress. Post caesarean section patient could not be extubated from general anaesthesia. Emergency computed tomography scan of the bra...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1047-7
更新日期:2009-12-01 00:00:00
abstract:INTRODUCTION:Postpartum cerebral angiopathy (PCA) is a rare and pathophysiologically ill-characterized cerebral vasoconstriction syndrome, occurring within 30 days of a usually uncomplicated pregnancy and delivery. Its onset has been associated with the use of vasoactive medications, particularly ergot alkaloids. Other...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-006-0194-3
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Almost 50% of the patients experience moderate-to-severe pain during endometrial biopsy. The study aimed to examine the effectiveness of intrauterine lidocaine for relieving pain during endometrial biopsy. METHODS:A randomised trial was conducted in 120 patients undergoing endometrial biopsy. Sixty-seven women...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-013-3036-0
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:There are many studies documenting increased prevalence of periodontal infection in women with preeclampsia. But, very few studies have attempted to establish causal relationship between the two. OBJECTIVE:To find out causal circumstantial evidence by isolating specific periodontal pathogens in oral and pla...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-2012-9
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To study the relation of pelvic pain symptoms and pelvic adhesions to Doppler ultrasound findings in patients with ovarian endometriomas. METHODS:62 patients who underwent laparoscopic surgery for endometrioma were divided into two groups according to their pelvic pain symptoms. Group 1 (n = 27) included patie...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2630-x
更新日期:2013-04-01 00:00:00
abstract:INTRODUCTION:Craniosynostosis is a condition characterized by a premature closure of one or more skull sutures and refers to a wide spectrum of cranial malformation with an estimated birth of 1:2,000-1:4,000 live births. Four receptors (FGFR 1, FGFR 2, FGFR 3, FGFR 4) involving mutation in the fibroblast growth factor ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-010-1643-6
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to establish a nomogram for renal parenchymal thickness throughout pregnancy. METHODS:One-hundred and twenty-eight healthy women with singleton, well-dated, uncomplicated second- or third-trimester pregnancies were prospectively evaluated for renal parenchymal thickness on routine ul...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2376-5
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To evaluate the effect of a modified type II radical hysterectomy on maternal morbidities and mortality in cases with abnormally invasive placenta (AIP). METHODS:63 cases with AIP were managed at one of the largest referral centers in Egypt in a prospective study design. This technique entails devascularizatio...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-5027-7
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:This study was designed to evaluate the role of hysteroscopy and endometrial biopsy in women with unexplained infertility. PATIENTS AND METHODS:Women with unexplained infertility were included in this prospective study, evaluated with transvaginal sonography and diagnostic hysteroscopy. Diagnostic hysterosc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-2931-8
更新日期:2014-01-01 00:00:00
abstract::Vaginal hysterectomy is less invasive than hysterectomy performed via the abdominal approach. The vaginal approach may be made difficult by prior conisation, a need to remove the adnexae or marked uterine enlargement requiring morcellement. In this retrospective study we have investigated the impact of these factors o...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02390389
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the prevalence of human papillomavirus (HPV) genotypes infection in women with and with normal cervical histology in the littoral region of Shandong, China. METHODS:Scrape specimens were collected from 4,601 women for Pap smear and HPV genotypes identification. 1,...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1584-0
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Hysterectomies are preformed abdominally, vaginally, laparoscopic or with robotic assistance. When choosing the route of hysterectomy, the physician should take into consideration the safest and most cost-effective route to fulfill all needs of the patient. METHODS:Data were collected retrospectively from 9...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3594-9
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:With an estimated incidence of one to two per one million women, the endometrial stromal sarcoma (ESS) is a rare disease. It is subclassified into a high-grade and a prognostically better low-grade type. Evidence-based data for a standardized therapy is lacking. CASE REPORT:A 32-year-old obese nulligravid...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0100-4
更新日期:2006-04-01 00:00:00
abstract:PURPOSE:To evaluate the effect of perioperative blood transfusions on the risk of recurrence of endometrial cancer. METHODS:This study is a retrospective analysis of 358 consecutive patients, without a history of other tumors, who underwent surgery for endometrial cancer between January 2000 and April 2010. RESULTS:W...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2668-9
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:Recent evidence suggests that assisted reproductive technology (ART) increases the risk of adverse pregnancy outcomes, including placental disorders. Similarly, endometriosis resulted detrimental on placenta previa. However, up to 50% of women with endometriosis suffer from infertility, thus requiring ART....
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析
doi:10.1007/s00404-018-4765-x
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To assess adverse pregnancy outcomes in patients complicated with mild or severe Hyperemesis Gravidarum (HG). METHODS:A retrospective cohort study of women aged 18-45 with a singleton pregnancy that were admitted to the gynecological ward at the Soroka University Medical Center due to HG between the years 2013...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05192-y
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:It is suspected that delayed surgery after neoadjuvant chemotherapy (NACT) leads to a worse outcome in breast cancer patients. We therefore evaluated possible influencing factors of the time interval between the end of NACT and surgery. METHODS:All patients receiving NACT due to newly diagnosed breast cancer f...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05494-6
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:The present study aims to evaluate whether multiplex ligation-dependent probe amplification (MLPA) technique with subtelomeric probes is to be an alternative method of routine G-banding chromosome analysis from pregnancy loss. METHODS:A review of 5 years (from 2005 to 2009) of karyotype for products of concept...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3403-5
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To investigate whether episiotomy prevents 3rd or 4th degree perineal tears in critical conditions such as shoulder dystocia, instrumental deliveries (vacuum or forceps), persistent occiput-posterior position, fetal macrosomia (>4,000 g), and non-reassuring fetal heart rate (NRFHR) patterns. METHODS:A retros...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2460-x
更新日期:2012-12-01 00:00:00
abstract::This is a report of a 18 year-old woman with two consecutive fetuses suffering from a Dandy-Walker malformation (DWM). The first diagnosis of Dandy-Walker syndrome was at 24 weeks gestation. According to the parent's request, this pregnancy was terminated. Seven months after that event a new case of Dandy-walker malfo...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02390945
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:Substantial histopathology data provide evidence that endometriosis might be viewed as a precursor lesion of endometrioid and clear cell carcinoma of the ovary, via intermediary atypical borderline lesions. Also, genes involved in both endometriosis and epithelial ovarian cancer have been shown to play a r...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-1957-z
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:Osseous metaplasia is a rare pathological entity that affects the uterus and usually appears following abortion, chronic endometritis, metabolic disorders or following LEEP excision of the cervix. CASE:Herein, we present the occurrence of osseous metaplasia in a 27-year-old patient with a history of an abort...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0515-1
更新日期:2008-06-01 00:00:00
abstract:PURPOSE:This study aimed to investigate the extent of knowledge and use of emergency contraception among women of reproductive age and to identify barriers existing in Turkey in this context. There is limited research regarding the knowledge and use and barriers to emergency contraception use, since the prepackaged for...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1267-x
更新日期:2010-09-01 00:00:00