Abstract:
:The possible pathologic consequences of the presence of circulating immune complexes in certain disease states has caused considerable attention to be given to the development of laboratory procedures capable of quantitatively measuring the presence of immune complexes in serum. Many assays are available which utilize differing properties of immune complexes for their detection. Examples of assays which depend on different biologic properties of circulating immune complexes are presented and discussed. Included are the Raji cell assay, Clq binding assay, inhibition of rheumatoid agglutination, and nephelometric assays for determination of circulating immune complexes.
journal_name
Ann Clin Lab Scijournal_title
Annals of clinical and laboratory scienceauthors
Blackstock Rsubject
Has Abstractpub_date
1981-05-01 00:00:00pages
262-8issue
3eissn
0091-7370issn
1550-8080journal_volume
11pub_type
杂志文章,评审abstract::Various fungal products, such as gliotoxin (GT), have immunomodulating activity, a fact exploited previously by our group for prevention of autoimmune diabetes mellitus in BB/Wor rats. To understand better the immunologic effects in GT-treated rats, splenocytes from 65-day-old prediabetic diabetes-prone rats were phen...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::BCR/ABL1 transcripts, the molecular hallmarks of chronic myeloid leukemia (CML), have been detected in peripheral blood from healthy individuals. Although CML is a sporadic disease, familial occurrence has been reported. This raises the question of whether there is a hereditary factor related to the etiology of CML. O...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2019-11-01 00:00:00
abstract::Patent ductus arteriosus (PDA) is highly prevalent in pre-term neonates (PTN) and has been recognized as a neonatal co-morbidity. The purpose of this study was to determine if levels of brain (or B-type) natriuretic peptide (BNP), a peptide secreted by ventricular myocytes in response to volume or pressure overload, c...
journal_title:Annals of clinical and laboratory science
pub_type: 临床试验,杂志文章
doi:
更新日期:2011-04-01 00:00:00
abstract::Diabetes-induced hyperglycemia has a direct damaging effect on ovarian function. Despite its deadly impact on ovaries, the mechanism of this condition has not been fully elucidated. Glucose transporters are involved in glucose uptake and utilization. Many transporters have been detected in the ovaries, but their roles...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2019-11-01 00:00:00
abstract::Secretion of nickel into unstimulated and stimulated saliva of rabbits was studied after a single intraperitoneal injection of nickel chloride labelled with 63Ni. Maximum 63Ni in unstimulated saliva was obtained in specimens collected one hr after maximum serum-63Ni was reached and two hrs after the nickel administrat...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1979-11-01 00:00:00
abstract::To evaluate the screening power of the fecal cytokeratin-19 test (CK-19) and the fecal occult blood test (FOBT), we performed rapid fecal CK-19 and FOBT tests on 515 stool samples from patients with various GI diseases and 814 stool samples from control patients. The rapid fecal CK-19 test (developed by DiNonA Researc...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:This study aims to develop a strategy for distinguishing Yersinia pestis of the Xilingele Plateau ecotype from other biovar of Yersinia pestis using insertion sequences. METHODS:Genome computational analysis was used to discover the positions of insertion sequences unique to Yersinia pestis 91001. PCR was us...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2019-09-01 00:00:00
abstract::Point-of-care testing (POCT) has been used for illicit substance screening in several settings, primarily in law enforcement and drug treatment centers. In this study, we evaluate the use of this screening approach in the emergency department (ED) of a tertiary-care, urban medical center. Aliquots of urine specimens w...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::We previously reported that proper dilution of sera that contain IgG monoclonal proteins (M-proteins) is necessary for accurate quantitation of serum albumin and M-protein concentrations separated by serum protein electrophoresis (SPE) using the Beckman PARAGON agarose electrophoresis system. We now report the signifi...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract::To assess mitochondrial function (pyruvate dehydrogenase [PDH] activity), cells were grown in the appropriate media to confluence, rinsed and incubated in glucose free media containing 25 microM L-lactate and [1-14C]-D,L-lactate. Lactate oxidation was measured as the amount of lactate oxidized in nmol of 14CO2 generat...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::The present study was performed to determine if any hormone measured in cord blood correlates with the size of the neonatal breast or the presence of galactorrhea. A total of 144 term newborn infants were examined. Estradiol (E2), progesterone (P), testosterone (T), and thyrotropin (TSH) were determined by radioimmuno...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Increased red cell lipid peroxidation (LP) occurs in the presence of ionized iron, as well as with various heme moieties and other transition metal ions. In stored erythrocytes, the degree of LP, as determined by plasma malondialdehyde measurements, can be significantly reduced by the addition of various metal chelati...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Utilizing fetal electrocardiography, ultrasound, M-mode and two dimensional echocardiography, fetal cardiac function, structure, and rhythm were studied in pregnancies with obstetrical risk factors. Risk factors for fetal cardiac abnormalities were defined to include: maternal diabetes, connective tissue disorders; Rh...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract::Ultrastructural studies with the transmission (TEM) and scanning (SEM) electron microscopes have added greatly to our knowledge of cellular structure and function in the liver. The normal polyhedral hepatocyte has numerous subcellular organelles, such as mitochondria, peroxisomes, lysosomes and complex rough (rer) and...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
doi:
更新日期:1984-03-01 00:00:00
abstract::Lead poisoning is an ancient and modern problem. Since many artists have had exposure to lead, it is appropriate to use some of their works as a vehicle to depict the symptoms of the variable syndromes associated with lead exposure. ...
journal_title:Annals of clinical and laboratory science
pub_type: 历史文章,杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVE:MiR-15 is involved in modulating many cellular processes that are normally destroyed in disease. The regulation of the cell cycle, angiogenesis, and responses to cellular stress are notable processes influenced by MiR-15. MiR-15 plays a critical role in the model of inflammation-related angiogenesis defects. ...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2019-09-01 00:00:00
abstract:CONTEXT:Myotonic dystrophies (DMs) are a group of autosomal dominant neuromuscular disorders which are caused by large CTG/CCTG-repeat expansions in untranslated regions of DMPK/ZNF9 gene. The "phenotypic overlap" in DMs creates complication in distinguishing patients with DM1 from patients with DM2 and underscores the...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2015-10-01 00:00:00
abstract:GOALS:This study aims to examine the effects of raising the reporting age for benign endometrial cells (BEC) on Papanicolaou (Pap) tests according to the 2014 3rd edition of the Bethesda System for Cervical Cytology, as well as the sequelae of the 2012 American Society of Colposcopy and Cervical Pathology (ASCCP) guide...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Human mammary tumor virus (HMTV) is 90-95% homologous to mouse mammary tumor virus, one of the causal agents of murine mammary tumors. Although HMTV has been frequently detected in human breast cancers, its clinical and prognostic value remains unknown. METHODS:In the present study, we analyzed HMTV infecti...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2019-03-01 00:00:00
abstract::The concentrations of progesterone, cortisol, estradiol, and transcortin binding capacity (TBC) were measured in plasma samples of women during normal pregnancy. Between 10 weeks and 20 weeks gestation, the mean of TBC increased linearly, and the mean increase in TBC for a given estradiol increment was constant until ...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::We report 2 patients who presented with vasomotor symptoms and severe thrombocytopenia following rattlesnake bites. These symptoms persisted in spite of treatment with antivenin and transfusion of multiple doses of platelets. Thrombocytopenia is a common occurrence in moderate to severe crotaline envenomation. Algorit...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract::To define further the nature of the decreased responsiveness of neonatal neutrophils to chemotactic factor stimulation, neutrophil shape change induced by various concentrations of N-formyl-methionyl-leucyl-phenyl-alanine (fMLP) was studied using a whole blood assay. Samples from 48 full term neonates and paired healt...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Mean platelet volume (MPV) is an inexpensive, routinely measured clinical parameter, and its elevation shows an increase in the size and activity of platelets. It has been shown that MPV can be used as a prognostic biomarker in certain chronic diseases. In the present study, MPV in patients with hepatitis B ...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2018-09-01 00:00:00
abstract::A 55-year-old Korean woman was initially diagnosed with acute myelomonocytic leukemia (AML). After induction chemotherapy was performed using cytarabine, idarubicin, and G-CSF, complete remission (CR) was subsequently achieved following reinduction chemotherapy using the same chemotherapeutic agents. Thirty-six months...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract::Determination of creatinine clearance (Ccr) is not a reliable indicator of glomerular filtration rate (GFR), owing to tubular secretion of creatinine. It has been reported that Ccr measurements can approximate true GFR after cimetidine (Ci) administration. In this study, GFR was estimated by Cockcroft and Gault's equa...
journal_title:Annals of clinical and laboratory science
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract::To investigate the relationships between obesity and serum lipid concentrations, we measured eight anthropometric parameters, body mass index (BMI), total body fat (TBF), and serum lipid profiles in 790 apparently healthy adolescents. TBF was assessed using a body fat analyzer. Serum concentrations of triglyceride, to...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:For viral load (VL) analysis of hepatitis C virus (HCV) by Real Time PCR, approved collection tubes were lavender top (LTT) and plasma processing (PPT) tubes, that differ in that PPTs include plasma separator. Using a Real Time PCR method, we investigated how the results correlated for the two tube types. M...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2018-05-01 00:00:00
abstract::Prospective HLA-DR matching has been shown to enhance renal graft survival. It has also been demonstrated that the major stimuli in the one-way mixed lymphocyte culture reaction (MLR) are the DR rather than DQ class II histocompatibility antigens. A two antigen DR match between the potential recipient and donor is usu...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1987-09-01 00:00:00
abstract::HbA1 is the result of the non-enzymatic glycosylation of HbA. HbA1 reflects the integrated blood glucose level that prevailed over a period of weeks; it thus has clinical application in the assessment of the long-term blood glucose control. This ability to determine easily the long-term blood glucose should enable the...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
doi:
更新日期:1980-03-01 00:00:00
abstract::The sequence of contraction-relaxation for myocardial cells is believed to be linked to Ca2+ flux across the sarcoplasmic reticulum. Alterations of sarcoplasmic reticulum function during ischemia may result in depressing the myocardial contraction-relaxation sequence. This study examines the relationship between the m...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1983-11-01 00:00:00