Disentangling the molecular genetic basis of personality: from monoamines to neuropeptides.

Abstract:

:The present review/perspectives article provides a short overview of our current understanding of the molecular genetics of personality. In the first part, the most important gene candidates such as COMT or SLC6A4 gene are presented. Since several seminal review studies have recently been published on different facets of molecular genetics and personality/emotionality, we focus the second half of the present article on new relevant research directions. This includes a stronger focus on animal research based testing of candidate genes (e.g. neuropeptides such as oxytocin and vasopressin) and the use of á priori genotyping to increase statistical power. Moreover, we stress the importance of integrating cross-cultural data in future research designs and of inclusion of epigenetic measures in neuroscientifically oriented personality research. Finally, the Affective Neuroscience Personality Scales are introduced as a new promising tool for biologically oriented psychology/psychiatry research.

journal_name

Neurosci Biobehav Rev

authors

Montag C,Reuter M

doi

10.1016/j.neubiorev.2014.04.006

subject

Has Abstract

pub_date

2014-06-01 00:00:00

pages

228-39

eissn

0149-7634

issn

1873-7528

pii

S0149-7634(14)00090-6

journal_volume

43

pub_type

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