Abstract：
:Brain injury survivors, particularly those injured early in life are very likely to abuse drugs and alcohol later in life. Alcohol abuse following traumatic brain injury (TBI) is associated with poorer rehabilitation outcomes and a greatly increased chance of suffering future head trauma. Thus, substance abuse among persons with brain injury reduces the chances for positive long-term outcomes and greatly increases the societal costs. In this review, we discuss the evidence for modulation of drinking behavior after TBI and the costs of problem drinking after TBI from both a biomedical and economic perspective. Further, we review the existing animal models of drinking after brain injury and consider the potential underlying psychosocial and neurobiological mediators of this phenomenon. In particular, we highlight the potential interactions among TBI, neuroinflammation and alcohol abuse. Substance abuse is a major problem in this vulnerable patient population and a greater understanding of the underlying biology has the potential to greatly improve outcomes.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Weil ZM,Corrigan JD,Karelina Kdoi
10.1016/j.neubiorev.2016.01.005subject
Has Abstractpub_date
2016-03-01 00:00:00pages
89-99eissn
0149-7634issn
1873-7528pii
S0149-7634(15)30235-9journal_volume
62pub_type
杂志文章,评审abstract：:Physiological and behavioral reproductive changes in the female rat which occur under constant bright illumination (LL) are examined. The development of LL-induced persistent estrus (PE) is discussed first in relation to other conditions in which PE is displayed. Next, mechanisms are reviewed which may account for the...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(82)90049-5
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abstract：:Our recent studies on seizure-triggering mechanisms in the kindling model of epilepsy are reviewed. Electroencephalographic (EEG) events during kindling-inducing tetanic stimulation from the site of stimulation were recorded, with an emphasis on EEG suppression and rhythmic synchronous discharge. From electrophysiolog...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2017.02.016
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析
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更新日期：2018-11-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.06.029
更新日期：2016-09-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(99)00044-5
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2012.07.008
更新日期：2012-11-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2018.03.027
更新日期：2018-07-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2014.10.013
更新日期：2014-11-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2013.09.010
更新日期：2013-12-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(05)80221-0
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.07.010
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(94)00056-7
更新日期：1995-07-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(98)00028-1
更新日期：1998-01-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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更新日期：2012-03-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/0149-7634(82)90034-3
更新日期：1982-01-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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更新日期：1996-01-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
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更新日期：2001-07-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2013.01.016
更新日期：2013-07-01 00:00:00
abstract：:A systematic review with meta-analysis was performed to: 1) estimate the prevalence of both mental and physical health problems in older offenders; 2) calculate relative risks for the health conditions in relation to non-offender older adults and; 3) explore the potential confounding role of several variables. We sear...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2020.07.043
更新日期：2020-11-01 00:00:00
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journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(94)90012-4
更新日期：1994-01-01 00:00:00
abstract：:Several newer magnetic resonance imaging (MRI) techniques are increasingly being applied to the study of white matter development and pathology across the lifespan. These techniques go beyond traditional macrostructural volumetric methods and provide valuable information about underlying tissue integrity and organizat...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2006.06.003
更新日期：2006-01-01 00:00:00
