Abstract:
:There is an emerging body of evidence associating children having autism spectrum disorder (ASD) with gastrointestinal (GI) symptoms, such as abdominal pain, chronic diarrhea, constipation, vomiting, gastroesophageal reflux, intestinal infections, and increased intestinal permeability. Moreover, in many studies, large differences in the composition of intestinal microbiota and metabolic products between ASD patients and controls were reported. Deepening the role and the biology of the gut microbiome may be fundamental to elucidate the onset of GI symptoms in ASD individuals and their etiopathogenetic causes. The gut-brain axis may affect brain development and behaviors through the neuroendocrine, neuroimmune, and autonomic nervous systems.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Bjørklund G,Pivina L,Dadar M,Meguid NA,Semenova Y,Anwar M,Chirumbolo Sdoi
10.1016/j.neubiorev.2020.06.033subject
Has Abstractpub_date
2020-11-01 00:00:00pages
111-120eissn
0149-7634issn
1873-7528pii
S0149-7634(20)30460-7journal_volume
118pub_type
杂志文章,评审abstract::Cardiometabolic risk factors may be of key importance in the development of future brain diseases like dementia or depression. However, it remains unclear how these risk factors exactly affect the brain. Advanced MR imaging methods such as, diffusion weighted and functional MRI, can provide detailed insights into subt...
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journal_title:Neuroscience and biobehavioral reviews
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journal_title:Neuroscience and biobehavioral reviews
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journal_title:Neuroscience and biobehavioral reviews
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